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Jan Pieter Abrahams
University of Basel
192Publications
35H-index
6,728Citations
Publications 192
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#1Thorsten Blum (University of Basel)H-Index: 1
#2Sevasti FilippidouH-Index: 6
Last.Jan Pieter Abrahams (University of Basel)H-Index: 35
view all 5 authors...
Bacteria swim and swarm by rotating the micrometers long, helical filaments of their flagella. They change direction by reversing their flagellar rotation, which switches the handedness of the filament’s supercoil. So far, all studied functional filaments are composed of a mixture of L- and R-state flagellin monomers. Here we show in a study of the wild type Firmicute Kurthia sp., that curved, functional filaments can adopt a conformation in vivo that is closely related to a uniform, all-L-state...
#1Andrea Merg (Emory University)H-Index: 1
#2Gavin Touponse (Emory University)H-Index: 1
Last.Vincent P. Conticello (Emory University)H-Index: 35
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#1Mauro Gemmi (IIT: Istituto Italiano di Tecnologia)H-Index: 24
#2Enrico Mugnaioli (IIT: Istituto Italiano di Tecnologia)H-Index: 22
Last.Jan Pieter Abrahams (University of Basel)H-Index: 35
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Crystallography of nanocrystalline materials has witnessed a true revolution in the past 10 years, thanks to the introduction of protocols for 3D acquisition and analysis of electron diffraction data. This method provides single-crystal data of structure solution and refinement quality, allowing the atomic structure determination of those materials that remained hitherto unknown because of their limited crystallinity. Several experimental protocols exist, which share the common idea of sampling ...
Multi-slice simulations of electron diffraction by three-dimensional protein crystals have indicated that structure solution would be severely impeded by dynamical diffraction, especially when crystals are more than a few unit cells thick. In practice, however, dynamical diffraction turned out to be less of a problem than anticipated on the basis of these simulations. Here it is shown that two scattering phenomena, which are usually omitted from multi-slice simulations, reduce the dynamical effe...
#1Mina Moradi (Paul Scherrer Institute)H-Index: 3
#2N.L. Opara (University of Basel)H-Index: 3
Last.Patrick Shahgaldian (University of Applied Science and Arts Northwestern Switzerland FHNW)H-Index: 23
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Stable, single-nanometer thin, and free-standing two-dimensional layers with controlled molecular architectures are desired for several applications ranging from (opto-)electronic devices to nanoparticle and single-biomolecule characterization. It is, however, challenging to construct these stable single molecular layers via self-assembly, as the cohesion of those systems is ensured only by in-plane bonds. We herein demonstrate that relatively weak noncovalent bonds of limited directionality suc...
#1Max T. B. Clabbers (University of Basel)H-Index: 4
#2Tim GrueneH-Index: 13
Last.Jan Pieter Abrahams (University of Basel)H-Index: 35
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Compared with X-rays, electron diffraction faces a crucial challenge: dynamical electron scattering compromises structure solution and its effects can only be modelled in specific cases. Dynamical scattering can be reduced experimentally by decreasing crystal size but not without a penalty, as it also reduces the overall diffracted intensity. In this article it is shown that nanometre-sized crystals from organic pharmaceuticals allow positional refinement of the hydrogen atoms, even whilst ignor...
#1Brijith Thomas (LEI: Leiden University)H-Index: 2
#2Rajeev K. Dubey (TU Delft: Delft University of Technology)H-Index: 9
Last.Huub J. M. de Groot (LEI: Leiden University)H-Index: 31
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The molecular geometry and supramolecular packing of two bichromophoric prototypic light harvesting compounds D1A2 and D2A2, consisting of two naphthylimide energy donors that were attached to the 1,7 bay positions of a perylene monoimide diester energy acceptor, have been determined by a hybrid approach using magic angle spinning NMR and electron nano crystallography (ENC), followed by modelling. NMR shift constraints, combined with the P-1 space group obtained from ENC, were used to generate a...
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