Samuel A. Silver
Queen's University
Intensive care medicineDialysisAcute kidney injuryDiabetes mellitusMedicine
What is this?
Publications 61
#1Alison Thomas (U of T: University of Toronto)H-Index: 1
#2Samuel A. Silver (Queen's University)H-Index: 13
Last. Ron WaldH-Index: 44
view all 17 authors...
Rationale & Objective Surveillance blood work is routinely performed in maintenance hemodialysis (HD) recipients. Although more frequent blood testing may confer better outcomes, there is little evidence to support any particular monitoring interval. Study Design Retrospective population-based cohort study. Setting & Participants All prevalent HD recipients in Ontario, Canada, as of April 1, 2011, and a cohort of incident patients commencing maintenance HD in Ontario, Canada, between April 1, 20...
1 CitationsSource
#1Daniel H. Li (St. Michael's Hospital)
#2Ron Wald (International Council for the Exploration of the Sea)H-Index: 44
Last. William Beaubien-Souligny (UdeM: Université de Montréal)H-Index: 3
view all 15 authors...
Abstract Purpose Severe acute kidney injury (AKI) is associated with a significant risk of mortality and persistent renal replacement therapy (RRT) dependence. The objective of this study was to develop prediction models for mortality at 90-day and 1-year following RRT initiation in critically ill patients with AKI. Methods All patients who commenced RRT in the intensive care unit for AKI at a tertiary care hospital between 2007 and 2014 constituted the development cohort. We evaluated the exter...
#1Samuel A. Silver (Queen's University)H-Index: 13
#2Sarah E. Bota (International Council for the Exploration of the Sea)H-Index: 5
Last. Ron Wald (International Council for the Exploration of the Sea)H-Index: 44
view all 9 authors...
Background and objectives It is uncertain whether primary care physician continuity of care associates with a lower risk of death and hospitalization among patients transitioning to maintenance dialysis. Design, setting, participants, & measurements Using provincial-linked administrative databases in Ontario, Canada, we conducted a population-based study of incident patients who initiated maintenance dialysis between 2005 and 2014 and survived for at least 90 days. We defined high primary care p...
1 CitationsSource
#1Riley Katulka (U of A: University of Alberta)
#2Abdalrhman Al Saadon (U of A: University of Alberta)
Last. Oleksa G. Rewa (U of A: University of Alberta)H-Index: 8
view all 9 authors...
Introduction Renal replacement therapy (RRT) is associated with high mortality and costs; however, no clinical guidelines currently provide specific recommendations for clinicians on when and how to stop RRT in recovering patients. Our objective was to systematically review the current evidence for clinical and biochemical parameters that can be used to predict successful discontinuation of RRT.
#1Daniel Blum (St. Michael's Hospital)H-Index: 1
#2William Beaubien-Souligny (UdeM: Université de Montréal)H-Index: 3
Last. Ron Wald (St. Michael's Hospital)H-Index: 44
view all 9 authors...
Abstract Background Studies have shown that achieving a time in therapeutic range (TTR) for warfarin of greater than 60% is associated with a lower risk of bleeding. However, many patients on hemodialysis (HD) do not achieve this target. Local Problem We audited TTR achievement at the in-center HD unit of our hospital in 2017 and found that only 40% of patients had achieved a TTR>60%. Project Aims We aimed to improve the percentage of HD patients achieving target TTR within two years. Interventi...
#1Samuel A. Silver (Stanford University)H-Index: 13
#2Jin Long (Stanford University)H-Index: 12
Last. Glenn M. Chertow (Stanford University)H-Index: 109
view all 7 authors...
Abstract Objective The study objective was to compare outcomes for patients with and without acute kidney injury during hospitalizations when left ventricular assist devices are implanted. Methods By using the National Inpatient Sample from 2008 to 2013, we identified patients with an International Classification of Diseases, Ninth Revision procedure code for left ventricular assist device implantation (37.66). We ascertained the presence of acute kidney injury and acute kidney injury requiring ...
2 CitationsSource
#1Elliot J. Lee (International Council for the Exploration of the Sea)
#2Aakil Patel (International Council for the Exploration of the Sea)
Last. Amit X. GargH-Index: 81
view all 59 authors...
Hemodialysis is a life-sustaining treatment for persons with kidney failure. However, those on hemodialysis still face a poor quality of life and a short life expectancy. High-quality research evid...
#1Samuel A. Silver (Queen's University)H-Index: 13
#2Mitra K. Nadim (SC: University of Southern California)H-Index: 20
Last. Andrew Lewington (St James's University Hospital)H-Index: 17
view all 11 authors...
ABSTRACT As the incidence of acute kidney injury (AKI) increases, prevention strategies are needed across the healthcare continuum, which begins in the community. Recognizing this knowledge gap, the 22nd Acute Disease Quality Initiative was tasked to discuss the evidence for quality of care measurement and care processes to prevent AKI and its consequences in the community. Using a modified Delphi process, an international and interdisciplinary group provided a framework to identify and monitor ...
#1Daniel Blum (JGH: Jewish General Hospital)H-Index: 1
Last. Ron Wald (St. Michael's Hospital)H-Index: 44
view all 4 authors...
Purpose of review:Volume overload and hypovolemia-induced symptoms are common in the hemodialysis (HD) population and frequently result in emergency department visits and hospitalization. A structu...