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Laura Y. Wang
Memorial Sloan Kettering Cancer Center
26Publications
11H-index
437Citations
Publications 26
Newest
#1Victoria Harries (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 1
#2Laura Y. Wang (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 11
Last.Ian Ganly (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 44
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Abstract Background Multifocality in papillary thyroid carcinoma is common. The aim of this study is to determine whether patients with multifocal disease, treated with lobectomy alone, have an increased risk of contralateral lobe papillary thyroid carcinoma, regional recurrence, and poorer survival. Methods After institutional review board approval, papillary thyroid carcinoma patients managed from 1986 to 2015 with lobectomy alone were identified from an institutional database. Papillary thyro...
1 CitationsSource
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#1Ashok R. Shaha (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 78
#2Jocelyn C. Migliacci (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 22
Last.Ian Ganly (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 44
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Abstract Background Tumor, node, and metastasis staging in thyroid carcinoma is important for assessing prognosis. However, patients with stage III or IV disease have an overall survival rate of 90%. The change to 55 years of age as the cutoff will create stage migration and many patients will be downstaged. Methods We reviewed our database of 3,650 patients to analyze the impact of the new American Joint Committee on Cancer staging system. There were 994 men (27%) and 2,656 women (73%). The med...
3 CitationsSource
#1Laura Y. Wang (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 11
#2Jocelyn C. Migliacci (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 22
Last.Ian Ganly (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 44
view all 7 authors...
Background The aim of this study was to report our incidence of clinically evident neck recurrence, salvage neck management and subsequent outcomes in patients with papillary thyroid cancer. This is important to know so that patients with thyroid cancer can be properly councelled about the implications of recurrent disease and subsequent outcome. Methods An institutional database of 3664 patients with thyroid cancer operated between 1986 and 2010 was reviewed. Patients with non-papillary histolo...
3 CitationsSource
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#1Laura Y. Wang (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 11
#2Iain J. Nixon (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 25
Last.Ian Ganly (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 44
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Background The majority of differentiated thyroid cancer tends to present with limited locoregional disease, leading to excellent long-term survival after operative treatment. Even patients with advanced local disease may survive for long periods with appropriate treatment. The aim of this study is to present our institutional experience of the management of locally advanced differentiated thyroid cancer and to analyze factors predictive of outcome. Methods We reviewed our institutional database...
17 CitationsSource
#1William F. McNamara (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 4
#2Laura Y. Wang (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 11
Last.Ian Ganly (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 44
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Background The objective of this study was to determine the rate and pattern of nodal recurrence in patients who underwent a therapeutic, lateral neck dissection (LND) for papillary thyroid cancer (PTC) with clinically evident cervical metastases and to determine if there was any correlation between the extent of initial dissection and the rate and pattern of neck recurrence. Methods A total of 3,664 patients with PTC treated between 1986 and 2010 at Memorial Sloan Kettering Cancer Center were i...
8 CitationsSource
#1Laura Y. Wang (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 11
#2Benjamin R. Roman (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 12
Last.Ian Ganly (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 44
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Background Over the last 15 years, there has been a change in clinical practice for the detection of recurrence in all patients with papillary thyroid cancer (PTC). In the past, recurrence was detected by clinical examination supplemented with fine-needle aspiration cytology; however, routine neck ultrasonography (US) and measurements of serum thyroglobulin were introduced for follow-up in 2000 and are now used widely for recurrence surveillance. The aim of this study was to describe the effecti...
7 CitationsSource
#1Laura Y. Wang (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 11
#2Ian GanlyH-Index: 44
The significance of cervical lymph node metastases in differentiated thyroid cancer has been controversial and continues to evolve. Current staging systems consider nodal metastases to confer a poorer prognosis, particularly in older patients. Increasingly, the literature suggests that characteristics of the metastatic lymph nodes such as size and number are also prognostic. There is a growing trend toward less aggressive treatment of low-volume nodal disease. The aim of this review is to summar...
9 CitationsSource
#1Iain J. Nixon (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 25
#2Laura Y. Wang (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 11
Last.Jatin P. Shah (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 103
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Background: Age is a critical factor in outcome for patients with well-differentiated thyroid cancer. Currently, age 45 years is used as a cutoff in staging, although there is increasing evidence to suggest this may be too low. The aim of this study was to assess the potential for changing the cut point for the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) staging system from 45 years to 55 years based on a combined international patient cohort supplied by...
58 CitationsSource
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