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Steven A. Goldman
University of Copenhagen
535Publications
88H-index
43.7kCitations
Publications 535
Newest
Published on Jan 1, 2013
Elizabeth Juneman (VA: United States Department of Veterans Affairs), Reza Arsanjani4
Estimated H-index: 4
+ 4 AuthorsElizabeth Juneman (VA: United States Department of Veterans Affairs)
This study was designed to determine the potential therapeutic effects of a new sodium-hydrogen exchanger (NHE-1) inhibitor in the rat coronary artery ligation model of chronic heart failure. After the induction of acute myocardial infarction, rats were entered into a randomly designed pilot dose study from 0.3 mg/kg, 1.0 mg/kg, and 3.0 mg/kg. Solid state micrometer hemodynamics, echocardiographic, and pressure-volume relationships were measured after 6 weeks of treatment. Treatment with this NH...
Elfriede Ruttmann26
Estimated H-index: 26
(Innsbruck Medical University),
Marion Dietl2
Estimated H-index: 2
+ 27 AuthorsUmberto Benedetto20
Estimated H-index: 20
Abstract Objective The long-term benefits of multiple arterial revascularization (MAR) in coronary artery bypass grafting remain uncertain. The aim of this study was to investigate the clinical outcome, graft patency, and need for subsequent target revascularization of radial artery (RA) versus saphenous vein graft in patients undergoing MAR in both patient- and graft-specific analyses. Methods Between 2001 and 2016, we followed 1654 patients over a median of 7.4 years in a prospective, longitud...
Ikeotunye Royal Chinyere1
Estimated H-index: 1
(UA: University of Arizona),
Mathew D. Hutchinson35
Estimated H-index: 35
(UA: University of Arizona)
+ -3 AuthorsElizabeth Juneman8
Estimated H-index: 8
(UA: University of Arizona)
Introduction While radiofrequency ablation has revolutionized the management of tachyarrhythmias, the rate of arrhythmia recurrence is a large drawback. Successful substrate identification is param...
Published on May 13, 2019in Circulation 23.05
Anne R. Cappola40
Estimated H-index: 40
(UPenn: University of Pennsylvania),
Akshay S. Desai46
Estimated H-index: 46
(Brigham and Women's Hospital)
+ 11 AuthorsSamia Mora46
Estimated H-index: 46
(Brigham and Women's Hospital)
Thyroid hormones have long been known to have a range of effects on the cardiovascular system. However, significant knowledge gaps exist concerning the precise molecular and biochemical mechanisms ...
Published on Jun 18, 2019in Circulation 23.05
Anne R. Cappola40
Estimated H-index: 40
,
Akshay S. Desai46
Estimated H-index: 46
+ 11 AuthorsSamia Mora46
Estimated H-index: 46
Thyroid hormones have long been known to have a range of effects on the cardiovascular system. However, significant knowledge gaps exist concerning the precise molecular and biochemical mechanisms ...
Published on Jun 1, 2019in Cell Reports 7.82
Zhengshan Liu (URMC: University of Rochester Medical Center), Mikhail Osipovitch2
Estimated H-index: 2
(UCPH: University of Copenhagen)
+ 8 AuthorsMartha S. Windrem21
Estimated H-index: 21
(URMC: University of Rochester Medical Center)
Summary Astrocytic differentiation is developmentally impaired in patients with childhood-onset schizophrenia (SCZ). To determine why, we used genetic gain- and loss-of-function studies to establish the contributions of differentially expressed transcriptional regulators to the defective differentiation of glial progenitor cells (GPCs) produced from SCZ patient-derived induced pluripotent cells (iPSCs). Negative regulators of the bone morphogenetic protein (BMP) pathway were upregulated in SCZ G...
Published on May 1, 2019in The Annals of Thoracic Surgery 3.92
Jordan J. Lancaster6
Estimated H-index: 6
(UA: University of Arizona),
Pablo Sanchez2
Estimated H-index: 2
(UA: University of Arizona)
+ 7 AuthorsSteven A. Goldman88
Estimated H-index: 88
(UA: University of Arizona)
Abstract Background To treat chronic heart failure (CHF), we developed a robust, easy to handle bio absorbable tissue-engineered patch embedded with human neonatal fibroblasts and human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs). This patch was implanted on the epicardial surface of the heart covering the previously infarcted tissue. Methods Sprague-Dawley rats (6-8 weeks old) underwent sham surgery (N=12) or left coronary artery ligation (N=45). Three weeks after ligation ...
Published on May 1, 2019in Journal of the American College of Cardiology 18.64
Mario Gaudino28
Estimated H-index: 28
(Cornell University),
Umberto Benedetto20
Estimated H-index: 20
+ 23 AuthorsGiuseppe Nasso23
Estimated H-index: 23
Abstract Background Few studies have evaluated the effect of chronic calcium-channel blocker therapy (CCB) on the angiographic and clinical outcome of radial artery (RA) grafts used for coronary bypass surgery. Objectives The purpose of this study was to evaluate if CCB influences midterm clinical and angiographic outcomes of RA grafts. Methods Patient-level data of 6 angiographic randomized trials evaluating RA graft status at midterm follow-up were joined in this observational analysis. Cox re...
Published on Jan 1, 2019in Cell Stem Cell 21.46
Mikhail Osipovitch2
Estimated H-index: 2
(UCPH: University of Copenhagen),
Andrea Asenjo Martinez1
Estimated H-index: 1
(UCPH: University of Copenhagen)
+ 12 AuthorsXiaojie Li2
Estimated H-index: 2
(URMC: University of Rochester Medical Center)
Summary Huntington’s disease (HD) is characterized by hypomyelination and neuronal loss. To assess the basis for myelin loss in HD, we generated bipotential glial progenitor cells (GPCs) from human embryonic stem cells (hESCs) derived from mutant Huntingtin (mHTT) embryos or normal controls and performed RNA sequencing (RNA-seq) to assess mHTT-dependent changes in gene expression. In human GPCs (hGPCs) derived from 3 mHTT hESC lines, transcription factors associated with glial differentiation an...
Published on Jan 1, 2019
John N. Mariani1
Estimated H-index: 1
(URMC: University of Rochester Medical Center),
Lisa Zou2
Estimated H-index: 2
(URMC: University of Rochester Medical Center)
+ 0 AuthorsSteven A. Goldman88
Estimated H-index: 88
(URMC: University of Rochester Medical Center)
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