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John A. Shepherd
University of Hawaii
347Publications
47H-index
7,286Citations
Publications 347
Newest
#1Benjamin Hinton (UCSF: University of California, San Francisco)H-Index: 2
#2Lin Ma (KP: Kaiser Permanente)H-Index: 9
Last.John A. Shepherd (UH: University of Hawaii)H-Index: 47
view all 10 authors...
To determine if mammographic features from deep learning networks can be applied in breast cancer to identify groups at interval invasive cancer risk due to masking beyond using traditional breast density measures. Full-field digital screening mammograms acquired in our clinics between 2006 and 2015 were reviewed. Transfer learning of a deep learning network with weights initialized from ImageNet was performed to classify mammograms that were followed by an invasive interval or screen-detected c...
#1Yiwey Shieh (UCSF: University of California, San Francisco)H-Index: 7
#2Christopher G. Scott (Mayo Clinic)H-Index: 45
Last.KerlikowskeKarla (UC: University of California)H-Index: 74
view all 12 authors...
Background Obesity and elevated breast density are common risk factors for breast cancer, and their effects may vary by estrogen receptor (ER) subtype. However, their joint effects on ER subtype-specific risk are unknown. Understanding this relationship could enhance risk stratification for screening and prevention. Thus, we assessed the association between breast density and ER subtype according to body mass index (BMI) and menopausal status.
#1Fredrik Strand (KI: Karolinska Institutet)H-Index: 3
#2Edward Azavedo (KI: Karolinska Institutet)H-Index: 4
Last.Kamila Czene (KI: Karolinska Institutet)H-Index: 53
view all 8 authors...
Background High mammographic density is associated with breast cancer and with delayed detection. We have examined whether localized density, at the site of the subsequent cancer, is independently associated with being diagnosed with a large-sized or interval breast cancer.
#1Manila Hada (NIH: National Institutes of Health)H-Index: 1
#2Hannah Oh (College of Health Sciences, Bahrain)
Last.Gretchen L. Gierach (NIH: National Institutes of Health)
view all 19 authors...
Background Mammographic density (MD) is a strong breast cancer risk factor that reflects fibroglandular and adipose tissue composition, but its biologic underpinnings are poorly understood. Insulin-like growth factor binding proteins (IGFBPs) are markers that may be associated with MD given their hypothesized role in breast carcinogenesis. IGFBPs sequester IGF-I, limiting its bioavailability. Prior studies have found positive associations between circulating IGF-I and the IGF-I:IGFBP-3 ratio and...
#1Bennett K Ng (UCSF: University of California, San Francisco)
#2Markus J. Sommer (UCSF: University of California, San Francisco)H-Index: 3
Last.John A. Shepherd (UCSF: University of California, San Francisco)H-Index: 47
view all 0 authors...
#1Samantha Kennedy (LSU: Louisiana State University)
#2Phoenix Hwaung (LSU: Louisiana State University)
Last.Steven B. Heymsfield (LSU: Louisiana State University)H-Index: 101
view all 0 authors...
Three-dimensional optical (3DO) imaging systems that rapidly and accurately provide body shape and composition information are increasingly available in research and clinical settings. Recently, relatively low-cost and space efficient 3DO systems with the ability to report and track individual assessments were introduced to the consumer market for home use. This study critically evaluated the first 3DO imaging device intended for personal operation, the Naked Body Scanner (NBS), against referenc...
#1Phoenix Hwaung (Pennington Biomedical Research Center)
#2Moonseong Heo (Clemson University)H-Index: 38
Last.Steven B. Heymsfield (Pennington Biomedical Research Center)H-Index: 101
view all 7 authors...
#1Gertraud Maskarinec (UH: University of Hawaii)H-Index: 48
#2Meredith A. J. Hullar (Fred Hutchinson Cancer Research Center)H-Index: 10
Last.Johanna W. Lampe (UW: University of Washington)H-Index: 51
view all 11 authors...
#2Sarah Lynn WarnerH-Index: 1
Last.John A. Shepherd (UH: University of Hawaii)H-Index: 47
view all 7 authors...
Abstract In preparation for the International Society for Clinical Densitometry Position Development Conference (PDC) 2019 in Kuala Lumpur, Malaysia, a cross-calibration, and precision task force was assembled and tasked to review the literature, summarize the findings, and generate positions to answer four related questions provided by the PDC Steering Committee, which expand upon the current ISCD official positions on these subjects. 1: How should a provider with multiple dual-energy X-ray abs...
Background Breast density and body mass index (BMI) are used for breast cancer risk stratification. We evaluate whether the positive association between volumetric breast density and breast cancer risk is strengthened with increasing BMI.
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