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Gamal A. Mohamed
King Abdulaziz University
108Publications
20H-index
1,154Citations
Publications 117
Newest
#1Gamal A. Mohamed (Al-Azhar University)H-Index: 20
#2Sabrin R.M. Ibrahim (Taibah University)H-Index: 20
Last.Hani Z. Asfour (KAU: King Abdulaziz University)H-Index: 6
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Abstract Two new diaryl ether derivatives [aspergillethers A (4) and B (5)] and five known metabolites [(22E,24R)-stigmasta-5,7,22-trien-3-β-ol (1), stigmasta-4,6,8(14),22-tetraen-3-one (2), orcinol (3), and butyrolactones I (6) and VI (7)] were separated from the endophytic fungus Aspergillus versicolor (Aspergillaceae) isolated from the roots of Pulicaria crispa Forssk (Asteraceae) growing in Saudi Arabia. The structures of these compounds were determined by various spectral techniques (e.g., ...
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#1Ahmad O. NoorH-Index: 3
#2Diena M. AlmasriH-Index: 2
Last.Sabrin R.M. IbrahimH-Index: 20
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Recently, the metabolites separated from endophytes have attracted significant attention, as many of them have a unique structure and appealing pharmacological and biological potentials. Isocoumarins represent one of the most interesting classes of metabolites, which are coumarins isomers with a reversed lactone moiety. They are produced by plants, microbes, marine organisms, bacteria, insects, liverworts, and fungi and possessed a wide array of bioactivities. This review gives an overview of is...
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#1Hossam M. Abdallah (Cairo University)H-Index: 14
#2Noura Ahmed Hassan (Zagazig University)H-Index: 4
Last.Hany M. El-Bassossy (Zagazig University)H-Index: 17
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Abstract Vasodilators are important pharmacologic agents for managing and/or treating hypertension. Medicinal plants are considered as valuable source of bioactive compounds. We used a bioguided approach to isolate, identify, and investigate the possible vasodilation activities and mechanism(s) of the prepared methanol extract from aerial parts of Psiadia punctulata (MAPP), its bioactive fraction and active compounds. Vascular effects of MAPP were studied using isolated artery technique in the p...
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#1Amjad A. Elghamdi (KAU: King Abdulaziz University)
#2Hossam M. Abdallah (Cairo University)H-Index: 14
Last.Sabrin R.M. Ibrahim (Taibah University)H-Index: 20
view all 9 authors...
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#1Hossam M. AbdallahH-Index: 14
#2Esraa M. ZakariaH-Index: 2
Last.Hany M. El-BassossyH-Index: 17
view all 6 authors...
Exaggerated vasoconstriction plays important roles in vascular complication in aging and many diseases like diabetes. Here, we investigated the protective effect of Psiadia punctulata (PP) on advanced glycation end products (AGEs)-induced aggravated vasoconstriction. The effect of total methanol extract of PP leaves (PPT) on AGE-induced vascular injury was studied through bioassay-guided fractionation procedures in order to find the bioactive fraction and isolate the bioactive compounds. Vascula...
2 CitationsSource
#1Mohamed F.S. Banjar (KAU: King Abdulaziz University)
#2Gamal A. Mohamed (Al-Azhar University)H-Index: 20
Last.Sabrin R.M. Ibrahim (Taibah University)H-Index: 20
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Abstract Two new cycloartane-type triterpenoids, cycloschimperols A [cycloart-20,24-dien-3β-ol] (3) and B [26,27-dinor-3β-hydroxy cycloartan-25-al] (4) and two known compounds, 24-methylenecycloartane (1) and cycloart-25-en-3-one (2) were separated from the aerial parts of Euphorbia schimperi C. Presl (Euphorbiaceae). The structural characterization of these metabolites was achieved by various spectroscopic analyses, including 1D and 2D NMR and HRESIMS as well as comparison with the published da...
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#1Salsabeel Z. Basha (KAU: King Abdulaziz University)
#2Gamal A. Mohamed (Al-Azhar University)H-Index: 20
Last.Ahmed Abdel-Lateff (Minia University)H-Index: 14
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AbstractBenign prostatic hyperplasia (BPH) is a common disorder in men aged over 60 years and significantly contributes to the distressing lower urinary tract symptoms. Cucurbitacins are triterpene...
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#1Dina S. El-Agamy (Taibah University)H-Index: 11
#2Sabrin R.M. Ibrahim (Taibah University)H-Index: 20
Last.Gamal A. Mohamed (Al-Azhar University)H-Index: 20
view all 8 authors...
Abstract Endophytic fungi have known as a promising source of secondary metabolites. γ-Butyrolactones are a class of metabolites reported from Aspergillus genus, which attracted much attention for their bioactivities. This study aimed to assess the potential cardioprotective effects of aspernolide F (AF) separated from the endophytic fungus A. terreus against doxorubicin (DOX)-induced cardiotoxic effects in rats. Animals were treated with two different doses of AF for 10 days prior to DOX inject...
2 CitationsSource
#1Sabrin R.M. IbrahimH-Index: 20
#2Gamal A. MohamedH-Index: 20
Last.Hany M. Abo-HadedH-Index: 4
view all 5 authors...
1 CitationsSource
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