Match!
Naoshi Dohmae
Saitama University
309Publications
51H-index
12.9kCitations
Publications 309
Newest
#1Kentaro Nakashima (Tokushima Bunri University)H-Index: 8
#2Shintaro Iwashita (Iwaki Meisei University)
Last.Si-Young Song (Tokushima Bunri University)H-Index: 21
view all 11 authors...
It is critical for development of high-quality antibodies in research and diagnostics to predict accurately their cross-reactivities with “off-target” molecules, which potentially induce false results. Herein, we report a good example of such a cross-reactivity for an off-target due to a stereochemical environment of epitopes, which does not simply depend on amino acid sequences. We found that significant subpopulation of a polyclonal peptide antibody against Bcnt (Bucentaur) (anti-BCNT-C antibo...
#1Yudai Ishizawa (Keio: Keio University)
#2Yuki Niwa (Keio: Keio University)H-Index: 8
Last.Siro Simizu (Keio: Keio University)H-Index: 26
view all 6 authors...
#1Aya Yoshimura (Kyoto University)H-Index: 2
#2Shinichi Nishimura (Kyoto University)H-Index: 16
Last.Hideaki Kakeya (Kyoto University)H-Index: 36
view all 7 authors...
Myropeptins, novel lipopeptides, were isolated from the culture broth of a fungus Myrothecium roridum F27113. Myropeptin A1 comprises a linear 20 amino acid–peptide chain and a lauric acid capping the N-terminus. Myropeptin A1 formed a helix structure and showed biological activities including antifungal and hemolysis. Myropeptin B, a shorter analogue by two amino acid residues, showed neither helicity nor biological activity. These two amino acids at the C-terminus regulate the molecular functi...
#1Mika Yamamoto (Kadai: Kagoshima University)H-Index: 3
#2Yoichiro Harada (Kadai: Kagoshima University)H-Index: 2
Last.Ikuro Maruyama (Kadai: Kagoshima University)H-Index: 50
view all 9 authors...
Abstract Tumor cells secrete membrane vesicles of various sizes, termed extracellular vesicles (EVs), which have gained increasing attention as potential tumor diagnostic markers. Tumor-derived EVs are enriched with high-mannose-type glycans. Here, we report the affinity isolation of EVs from human melanoma A375 cells by using high-mannose-type glycan-specific agglutinin from Oscillatoria Agardhii (OAA). Glycan analysis of melanoma EVs revealed the presence of high-mannose-type glycans with stru...
#1Shintaro IwashitaH-Index: 18
#2Takehiro SuzukiH-Index: 33
Last.Kentaro NakashimaH-Index: 8
view all 7 authors...
The BCNT (Bucentaur) protein family is characterized by a conserved amino acid sequence at the C-terminus (BCNT-C domain) and plays an essential role in gene expression and chromosomal maintenance in fungi, fly, and chicken. The mammalian Bucentaur/Craniofacial developmental protein 1 (Bcnt/Cfdp1) is also a tentative component of the Srcap (SNF2-Related CBP Activator Protein) chromatin remodeling complex, but little is known about its properties, partly because there are few suitable antibodies ...
#1Shohei Takase (Meiji University)H-Index: 2
#2Rumi KurokawaH-Index: 1
Last.Ken MatsumotoH-Index: 28
view all 13 authors...
Thioviridamide, prethioviridamide, and JBIR-140, which are ribosomally synthesized and post-translationally modified peptides (RiPPs) possessing five thioamide bonds, induce selective apoptosis in various cancer cells, especially those expressing the adenovirus oncogene E1A. However, the target protein of this unique family of bioactive compounds was previously unknown. To investigate the mechanism of action, we adopted a combined approach of genome-wide shRNA library screening, transcriptome pr...
#1Saori Nonaka (Kanazawa University)H-Index: 4
#2Mai Sono (Kanazawa University)
Last.Yoshinobu Nakanishi (Kanazawa University)H-Index: 38
view all 7 authors...
Abstract We previously reported that Drosophila phagocytes enhance their phagocytic activity after apoptotic cell engulfment accompanied by the activation of the transcription repressor Tailless and an increase in the levels of engulfment receptors. We herein investigated the underlying mechanisms. We found that Tailless phosphorylation levels decreased in Drosophila phagocytes following the stimulation with apoptotic cells. Anticipating the involvement of another transcription repressor, we exa...
#1Takeshi Uemura (Chiba University)H-Index: 9
#2Takehiro SuzukiH-Index: 33
Last.Kazuei Igarashi (Chiba University)H-Index: 47
view all 10 authors...
Abstract We have recently found that conjugation of acrolein with a 50 kDa protein(s) is strongly associated with tissue damage during brain infarction. In the current study, the identity and function of the 50 kDa protein(s) conjugated with acrolein during brain infarction were investigated. The 50 kDa protein(s) conjugated with acrolein were identified as α- and β-tubulins. Ten cysteine residues in α- and β-tubulins (Cys25, 295, 347 and 376 in α-tubulin and Cys12, 129, 211, 239, 303 and 354 in...
#1Ryo Nagao (Okayama University)H-Index: 2
#2Koji Kato (Okayama University)
Last.Fusamichi Akita (Okayama University)H-Index: 12
view all 11 authors...
Light-harvesting antenna systems in photosynthetic organisms harvest solar energy and transfer it to the photosynthetic reaction centres to initiate charge-separation and electron-transfer reactions. Diatoms are one of the important groups of oxyphototrophs and possess fucoxanthin chlorophyll a/c-binding proteins (FCPs) as light harvesters. The organization and association pattern of FCP with the photosystem II (PSII) core are unknown. Here we solved the structure of PSII–FCPII supercomplexes is...
12345678910