Julie Chandler
Merck & Co.
PsychiatryPsychologyPhysical therapyClinical trialMedicine
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Publications 73
#1Zhongjian Xie (CSU: Central South University)
#2Weibo Xia (Peking Union Medical College Hospital)H-Index: 14
Last. Er-yuan Liao (CSU: Central South University)H-Index: 2
view all 13 authors...
Purpose: We aimed to investigate the status of serum 25-hydroxyvitamin D [25(OH)D] among Chinese postmenopausal women in a multicenter cross-sectional study. Methods: Non-institutionalized postmenopausal women aged ≥55 years were recruited from urban and rural areas in 7 geographically different regions in China. Subject enrollment was executed during the summer and the winter. Vitamin D insufficiency and deficiency were defined as 25(OH)D16.78ng/mL. Conclusions: The prevalence of vitamin D inad...
#1Inbal GoldschteinH-Index: 9
#2Allison Martin Nguyen (MSD: Merck & Co.)H-Index: 12
Last. Varda ShalevH-Index: 30
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Summary This study analyzed data on 87,224 osteoporotic patients with up to 18 years of computerized medical history. Patients with osteoporosis and type 2 diabetes had higher bone density yet more fractures than non-diabetic osteoporotic patients. Fracture incidence among the diabetic patients was associated with retinopathy and cardiovascular disease, but not with diabetes duration.
1 CitationsSource
#1Tiffini Voss (MSD: Merck & Co.)H-Index: 9
#2Ying Zhang (MSD: Merck & Co.)H-Index: 10
Last. Michael F. Egan (MSD: Merck & Co.)H-Index: 35
view all 15 authors...
#1Mark Marsico (MSD: Merck & Co.)H-Index: 2
#2James Kost (MSD: Merck & Co.)H-Index: 17
Last. Julie Chandler (MSD: Merck & Co.)H-Index: 35
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#1Erik A. ImelH-Index: 21
#2George J. EckertH-Index: 47
Last. Ziyue LiuH-Index: 16
view all 12 authors...
#1Subashan Perera (University of Pittsburgh)H-Index: 44
#2Kushang V. Patel (UW: University of Washington)H-Index: 45
Last. Stephanie A. Studenski (NIH: National Institutes of Health)H-Index: 45
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Background. Functional independence with aging is an important goal for individuals and society. Simple prognostic indicators can inform health promotion and care planning, but evidence is limited by heterogeneity in measures of function. Methods. We performed a pooled analysis of data from seven studies of 27,220 community-dwelling older adults aged 65 or older with baseline gait speed, followed for disability and mortality. Outcomes were incident inability or dependence on another person in ba...
111 CitationsSource
#1Mark Forrest Gordon (Boehringer Ingelheim)H-Index: 11
Last. Lori Frank (Patient-Centered Outcomes Research Institute)H-Index: 28
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Abstract Introduction As drug development research efforts move toward studying patients earlier in the course of Alzheimer's disease (AD), it is important to incorporate the patient's perspective into measurement of outcomes. Methods This article summarizes the qualitative work of the Patient-Reported Outcome Consortium's Cognition Working Group in the development of a new self-reported outcome measure in persons with mild cognitive impairment (MCI) due to suspected AD, herein referred to as MC...
9 CitationsSource
#1Mark Marsico (MSD: Merck & Co.)H-Index: 2
#2April Grant (MSD: Merck & Co.)H-Index: 1
Last. Julie Chandler (MSD: Merck & Co.)H-Index: 35
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#1Mark Marsico (MSD: Merck & Co.)H-Index: 2
#2Celeste A. de JagerH-Index: 20
Last. Julie ChandlerH-Index: 35
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Background: Amnestic mild cognitive impairment (aMCI) and mild-to-moderate Alzheimer’s disease (AD) are clinically distinct but impact cognitive and functional ability similarly. Comprehensive assessment of cognitive and functional deficits may prove useful in informing differential diagnosis in early stages of dementia and in informing endpoint selection in therapeutic AD trials. Objective: The objective of this study was to characterize patterns of cognitive and functional impairment in aMCI a...
1 CitationsSource
#1Peter J. Snyder (Brown University)H-Index: 43
#2Kristin Kahle-Wrobleski (Eli Lilly and Company)H-Index: 12
Last. Maria C. Carrillo (Alzheimer's Association)H-Index: 44
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Abstract Several lines of evidence from Alzheimer's disease (AD) research continue to support the notion that the biological changes associated with AD are occurring possibly several decades before an individual will experience the cognitive and functional changes associated with the disease. The National Institute on Aging—Alzheimer's Association revised criteria for AD provided a framework for this new thinking. As a result of this growing understanding, several research efforts have launched ...
39 CitationsSource