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Clíona Ní Cheallaigh
Trinity College, Dublin
Health careImmunologyTuberculosisPopulationMedicine
24Publications
9H-index
272Citations
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Publications 25
Newest
#1Helen Fogarty (RCSI: Royal College of Surgeons in Ireland)H-Index: 2
#1Helen Fogarty (RCSI: Royal College of Surgeons in Ireland)H-Index: 2
Last. Mary ByrneH-Index: 5
view all 15 authors...
Although the pathophysiology underlying severe COVID-19 remains poorly understood, accumulating data suggest that a lung-centric coagulopathy may play an important role. Elevated D-dimer levels which correlated inversely with overall survival were recently reported in Chinese cohort studies. Critically however, ethnicity has major effects on thrombotic risk, with a 3-4 fold lower risk in Chinese compared to Caucasians and a significantly higher risk in African-Americans. In this study, we invest...
14 CitationsSource
#1Helen Fogarty (RCSI: Royal College of Surgeons in Ireland)H-Index: 2
#2Liam Townsend (Trinity College, Dublin)H-Index: 2
Last. Mary ByrneH-Index: 5
view all 15 authors...
We are grateful for the comments of Marrietta et al, [1] and welcome the opportunity to provide further details on the coagulopathy observed in our patients with COVID-19 infection [2]. The weight-adjusted low molecular weight heparin (LMWH) thromboprophylaxis used in the study is that routinely used for hospital in-patients in our institution, consistent with national recommendations [3,4] With respect to the cohort of patients with COVID-19 enrolled in our study, it is important to highlight t...
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#1Marco MariettaH-Index: 15
#1Helen Fogarty (RCSI: Royal College of Surgeons in Ireland)H-Index: 2
Last. Mary ByrneH-Index: 5
view all 15 authors...
Abstract We read with interest the report from Fogarty and colleagues about COVID-19 coagulopathy in Caucasian patients. [1] However, we think that some aspects of this report may deserve further attention. The major concern regards the doses of low-molecular weight heparin (LMWH) used for thromboprophylaxis in this study. Indeed, the Authors report on a weight-adjusted dose of enoxaparin higher than that registered in Europe for the prophylaxis of venous thromboembolism (VTE) in hospitalized ac...
2 CitationsSource
#1Sinead Kiernan (Trinity College, Dublin)
#2David Mockler (Trinity College, Dublin)H-Index: 5
Last. Julie Broderick (Trinity College, Dublin)H-Index: 8
view all 4 authors...
Background: Adults who are experiencing homelessness suffer higher levels of premature mortality and age-related medical conditions compared to the general population, but little is known about physical factors that influence their health experience. This review aimed to evaluate what is known about physical functional limitations and physical activity levels, and how these constructs are measured in adults experiencing homelessness. Methods: This review was conducted in accordance with the Joan...
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#1Conor GrantH-Index: 1
#2Colm Bergin (Trinity College, Dublin)H-Index: 23
Last. Clíona Ní Cheallaigh (Trinity College, Dublin)H-Index: 9
view all 5 authors...
Background High-cost, high-need users are defined as patients who accumulate large numbers of emergency department visits and hospital admissions that might have been prevented by relatively inexpensive early interventions and primary care. This phenomenon has not been previously described in HIV-infected individuals. Methods We analyzed the health records of HIV-infected individuals using scheduled or unscheduled inpatient or outpatient health care in St James's Hospital, Dublin, Ireland, from ...
1 CitationsSource
#1Cathal McCrory (Trinity College, Dublin)H-Index: 17
#2Giovanni Fiorito (University of Sassari)H-Index: 1
Last. Rose Anne Kenny (Trinity College, Dublin)H-Index: 68
view all 11 authors...
Allostatic load (AL) and epigenetic clocks both attempt to characterize the accelerated aging of biological systems, but at present it is unclear whether these measures are complementary or distinct. This study examines the cross-sectional association of AL with epigenetic age acceleration (EAA) in a subsample of 490 community-dwelling older adults participating in The Irish Longitudinal study on Aging (TILDA). A battery of 14 biomarkers representing the activity of four different physiological ...
2 CitationsSource
#1Julie Broderick (Trinity College, Dublin)H-Index: 8
#2Alice WaughH-Index: 1
Last. Clíona Ní Cheallaigh (Trinity College, Dublin)H-Index: 9
view all 9 authors...
Socially marginalised groups suffer vastly poorer health outcomes compared to the general population. Inclusion health seeks to directly address the health inequities experienced by groups such as homeless people and refugees. Despite the unique healthcare needs experienced by these vulnerable groups, inclusion health features very little in health education curricula. This letter has been written by a group of clinicians, academics, clinical education specialists and students with a common inte...
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#1Aine Carroll (UCD: University College Dublin)H-Index: 1
#2Siobhan O'Brien (UCD: University College Dublin)
Last. Clíona Ní Cheallaigh (Trinity College, Dublin)H-Index: 9
view all 4 authors...
Introduction: Socially excluded individuals have higher morbidity and mortality, use a disproportionate amount of healthcare resources and generate a large volume of potentially preventable healthcare and other costs compared to more privileged individuals. Through a person-centred, whole-system and multi-disciplinary approach to care delivery, integrated care improves care for people with complex needs who are likely to have poor outcomes. Homeless and other socially excluded individuals freque...
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#1Éidín Ní Shé (UCD: University College Dublin)H-Index: 4
#2Sarah Morton (UCD: University College Dublin)H-Index: 2
Last. Thilo Kroll (UCD: University College Dublin)H-Index: 24
view all 11 authors...
OBJECTIVE: Public and patient involvement is increasingly embedded as a core activity in research funding calls and best practice guidelines. However, there is recognition of the challenges that prevail to achieve genuine and equitable forms of engagement. Our objective was to identify the mechanisms and resources that enable the reciprocal involvement of seldom heard groups in health and social care research. METHODS: A rapid realist review of the literature that included: (a) a systematic sear...
2 CitationsSource
#1Cathal McCrory (Trinity College, Dublin)H-Index: 17
#2Giovanni FioritoH-Index: 20
Last. Rose Anne Kenny (Trinity College, Dublin)H-Index: 68
view all 10 authors...
Abstract Individuals of lower socio-economic position (SEP) carry a heavier burden of disease and morbidity and live shorter lives on average compared with their more advantaged counterparts. This has sparked research interest in the processes and mechanisms via which social adversity gets biologically embedded. The present study directly compares the empirical worth of two candidate mechanisms: Allostatic Load (AL) and the Epigenetic Clock(s) for advancing our understanding of embodiment using ...
3 CitationsSource
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