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Nora Soberón
8Publications
3H-index
41Citations
Publications 8
Newest
Abstract Research question The study aimed to determine whether IVF or intrauterine growth restriction (IUGR) result in short neonatal telomeres, which could explain the higher risk of cardiovascular and metabolic disease described in these populations. Design This was an observational, analytical, cross-sectional, prospective study with controls in a tertiary hospital. The main outcome was to determine the leukocyte telomere length in 126 newborns and their mothers ( n = 109). Newborns were con...
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#2Montserrat CofánH-Index: 24
Last.Aleix Sala-VilaH-Index: 22
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Randomized controlled trials on diet and shortening of leukocyte telomere length (LTL) mostly focus on marine-derived n-3 polyunsaturated fatty acids (PUFA). Walnuts are a sustainable source of n-3 PUFA. We investigated whether inclusion of walnuts (15% of energy) in the diet for 2 years would maintain LTL in cognitively healthy elders (63–79 years old) compared to a control group (habitual diet, abstaining from walnuts). This opportunistic sub-study was conducted within the Walnuts and Healthy ...
1 CitationsSource
Many factors may converge in healthy ageing in the oldest old, but their association and predictive power on healthy o functionally impaired ageing has yet to be demonstrated. By detecting healthy ageing and in turn, poor ageing, we could take action to prevent chronic diseases associated with age. We conducted a pilot study comparing results of a set of markers (peripheral blood mononuclear cell telomere length or PBMC, circulating Aβ peptides, anti-Aβ antibodies, and ApoE status) previously as...
2 CitationsSource
#2Montserrat Cofán (ISCIII: Instituto de Salud Carlos III)H-Index: 24
Last.Aleix Sala-Vila (ISCIII: Instituto de Salud Carlos III)H-Index: 22
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Summary Background & aims Shortening of leukocyte telomere length (LTL) is a biomarker of aging. Epidemiologic studies of LTL in relation to dietary fatty acids have reported conflicting results. The red blood cell (RBC) fatty acid status is a valid objective biomarker of long-term dietary intake of C18:2n-6, C18:3n-3 and long-chain n-3 polyunsaturated fatty acids (C20:5n-3 and C22:6n-3). In healthy older individuals, we investigated whether LTL relates to the RBC proportions of the main dietary...
1 CitationsSource
#2Nora SoberónH-Index: 3
Last.Maria A. BlascoH-Index: 84
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// Miguel Quintela-Fandino 1 , Nora Soberon 2 , Ana Lluch 3 , Luis Manso 4 , Isabel Calvo 5 , Javier Cortes 6, 7 , Fernando Moreno-Anton 8 , Miguel Gil-Gil 9 , Noelia Martinez-Janez 7 , Antonio Gonzalez-Martin 10 , Encarna Adrover 11 , Raquel de Andres 12 , Gemma Vinas 13 , Antonio Llombart-Cussac 14 , Emilio Alba 15 , Silvana Mouron 1 , Juan Guerra 16 , Begona Bermejo 3 , Esther Zamora 6 , Jose Angel Garcia-Saenz 8 , Sonia Pernas Simon 9 , Eva Carrasco 17 , Maria Jose Escudero 17 , Ruth Campo 1...
3 CitationsSource
#2Tereza VaclovaH-Index: 3
Last.Javier BenitezH-Index: 75
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Oxidative stress is a source of DNA damage which can lead to genomic instability and telomere shortening. The OGG1 glycosidase plays an important role in the Base Excision Repair (BER) pathway that counteracts the oxidative DNA damage caused by endogenous cell stress. Recently, we have demonstrated that a single nucleotide polymorphism (SNP) in the OGG1 gene can modify cancer risk in carriers of germline mutations in the BRCA1 and BRCA2 genes1. Hence, we aimed to explore the possible role of thi...
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#2Tereza VaclovaH-Index: 3
Last.Javier BenitezH-Index: 75
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// Carlos Benitez-Buelga 1 , Tereza Vaclova 1 , Sofia Ferreira 1 , Miguel Urioste 2, 5 , Lucia Inglada-Perez 3, 5 , Nora Soberon 4 , Maria A. Blasco 4 , Ana Osorio 1, 5 , Javier Benitez 1, 5 1 Human Genetics Group, Spanish National Cancer Research Center (CNIO), Madrid 28029, Spain 2 Familial Cancer Clinical Unit, Spanish National Cancer Research Center (CNIO), Madrid 28029, Spain 3 Endocrine Cancer Group, Spanish National Cancer Research Center (CNIO), Madrid 28029, Spain 4 Telomere and Telomer...
9 CitationsSource
#1Juan Miguel Fernández-Alvira (Centro Nacional de Investigaciones Cardiovasculares)H-Index: 22
#2Valentin Fuster MDPhD (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 167
Last.Vicente Andrés (Centro Nacional de Investigaciones Cardiovasculares)H-Index: 43
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This study was supported by Instituto de Salud Carlos III (Grant RD12/0042/0028 to Dr. Andres), with cofunding from Fondo Europeo de Desarrollo Regional (FEDER), and by a noncompetitive, unrestricted grant shared equally between the CNIC and Banco de Santander. The PESA study is a noncommercial study that is independent of the health care and pharmaceutical industry. The Spanish Ministry of Economy and Competitiveness (MINECO) and the Pro CNIC Foundation support the CNIC. The MINECO RETOS Progra...
25 CitationsSource
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