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Tihana Žanić Grubišić
University of Zagreb
44Publications
11H-index
373Citations
Publications 46
Newest
#1Iva Hlapčić (University of Zagreb)
#2Anita Somborac-Bačura (University of Zagreb)H-Index: 3
Last.Lada RumoraH-Index: 13
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#1Andrea Hulina-Tomašković (University of Zagreb)H-Index: 2
#2Marija Grdić Rajković (University of Zagreb)H-Index: 5
Last.Lada Rumora (University of Zagreb)H-Index: 13
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#2Ana-Marija Domijan (University of Zagreb)H-Index: 25
Last.Lada Rumora (University of Zagreb)H-Index: 13
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AbstractContext: Increased oxidative burden is found in chronic obstructive pulmonary disease (COPD).Objective: To assess the association of ceruloplasmin, albumin, bilirubin, transferrin, thiols and malondialdehyde (MDA) with stable COPD.Materials and methods: Oxidative stress markers measured in 106 COPD patients and 45 healthy subjects were evaluated.Results: Higher ceruloplasmin and MDA, and lower albumin, transferrin and thiols in COPD patients were found. Ceruloplasmin was the strongest si...
5 CitationsSource
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#2Karmela BarišićH-Index: 12
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#1Lada Rumora (University of Zagreb)H-Index: 13
#2Tihana Žanić Grubišić (University of Zagreb)H-Index: 11
Last.Marija Grdić Rajković (University of Zagreb)H-Index: 5
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#2Karmela BarišićH-Index: 12
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Ekto-ATPaze su transmembranski enzimi koji sudjeluju u defosforilaciji izvanstanicnog ATP-a i ADP-a. Izvanstanicni ATP te drugi nukleotidi i nukleozidi su važne signalne molekule koje reguliraju razlicite ucinke u gotovo svim tkivima: kontraktilnost glatkih misica, vaskularni tonus, imunosni odgovor, nocicepciju, neurotransmisiju, embrionalni razvitak, hemostazu. Osim membranski vezanih oblika enzima, u tjelesnim tekucinama poput seruma mogu se pronaci i topljivi, enzimski aktivni oblici ekto-AT...
Background: Cigarette smoke is known as oxidative stress causing agent. For laboratory studies of its toxic effects on different cell models cigarette smoke extract (CSE) is used. The aim of this study was to evaluate the method for CSE preparation and to examine cytotoxic effect of CSE on polymorphonuclear leukocytes (PMN). Materials and Methods: 100 % CSE was freshly prepared by bubbling the smoke from two Kentucky 3R4F research-reference cigarettes through the 25 mL of cell culture medium wit...
#1Lada Rumora (University of Zagreb)H-Index: 13
#2Ana-Marija Domijan (University of Zagreb)H-Index: 25
Last.Maja Šegvić Klarić (University of Zagreb)H-Index: 15
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Abstract The aim of this study was to investigate the underlying mechanisms of OTA and CTN individual and combined toxicity in porcine kidney PK15 cells of proximal tubule origin. Activation and expression of mitogen-activated protein kinases (MAPKs) ERK, JNK and p38 were determined by Western blot analysis. MAPKs were differentially activated by single or dual OTA and CTN treatments. Single OTA and CTN stimulated transient ERK and prolonged JNK activation, while phospho-p38 signal was more pers...
10 CitationsSource
#1Lada Rumora (University of Zagreb)H-Index: 13
#2Marija Grdić Rajković (University of Zagreb)H-Index: 5
Last.Tihana Žanić Grubišić (University of Zagreb)H-Index: 11
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AbstractIntroduction: Paraoxonase 1 (PON1) is an antioxidative enzyme manly associated with high density lipoproteins (HDL) in the peripheral blood. The aim of this study was to determine the PON1 paraoxonase and arylesterase activities in patients with chronic obstructive pulmonary disease (COPD). We also aimed to determine the concentration of reduced thiol groups as a marker of protein oxidation. Materials and methods: The study included 105 patients with stable COPD and 44 healthy controls. ...
8 CitationsSource
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