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Melania Manco
Boston Children's Hospital
198Publications
44H-index
6,415Citations
Publications 198
Newest
#1Marzia BianchiH-Index: 2
#2Anna AlisiH-Index: 38
Last.Melania MancoH-Index: 44
view all 9 authors...
Source
#1P. Di BonitoH-Index: 10
#2Giuliana ValerioH-Index: 26
Last.Melania Manco (Boston Children's Hospital)H-Index: 44
view all 15 authors...
Objective To evaluate the association between high uric acid (UA), reduced estimated glomerular filtration rate (eGFR), and non-alcoholic fatty liver disease (NAFLD) in outpatient children and adolescents with overweight (OW) or obesity (OB).
Source
Post-translational modulation of peptidylprolyl isomerase Pin1 might link impaired glucose metabolism and neurodegeneration, being Pin1 effectors target for the glucagon-Like-Peptide1 analog liraglutide. We tested the hypotheses in Pin1 silenced cells (SH-SY5Y) treated with 2-deoxy-d-glucose (2DG) and methylglyoxal (MG), stressors causing altered glucose trafficking, glucotoxicity and protein glycation. Rescue by liraglutide was investigated. Pin1 silencing caused increased levels of reactive ox...
Source
#1Procolo Di BonitoH-Index: 11
Last.Giuliana Valerio (University of Naples Federico II)H-Index: 26
view all 15 authors...
BackgroundTwo different systems for the screening and diagnosis of hypertension (HTN) in children currently coexist, namely, the guidelines of the 2017 American Academy of Pediatrics (AAP) and the ...
Source
#1Procolo Di BonitoH-Index: 11
#2Maria Rosaria Licenziati (Boston Children's Hospital)H-Index: 13
Last.Giuliana Valerio (University of Naples Federico II)H-Index: 26
view all 9 authors...
We evaluated the performance of a new simple formula (NSF) for the screening of hypertension by American Academy of Pediatrics Guidelines 2017 (AAPG2017) in children with overweight/obesity (OW/OB). The performance of the NSF and the modified blood pressure to height ratio (MBPHR3) thresholds against AAPG2017 was evaluated; both methods were also compared to assess the association with concentric left ventricular hypertrophy (cLVH). The study included 3259 OW/OB children (5–13 years). Two center...
Source
#2Melania MancoH-Index: 44
Last.Esmeralda Capristo (Agostino Gemelli University Polyclinic)H-Index: 32
view all 13 authors...
Source
#1Nicola Spreghini (Boston Children's Hospital)H-Index: 1
#2Stefano Cianfarani (Boston Children's Hospital)H-Index: 30
Last.Melania Manco (Boston Children's Hospital)H-Index: 44
view all 9 authors...
Aim To investigate whether GE is affected in children/adolescents with obesity and abnormalities of the metabolic syndrome (MetS).
1 CitationsSource
#1Melania Manco (Boston Children's Hospital)H-Index: 44
#2Andrea MariH-Index: 56
Last.Beverley BalkauH-Index: 105
view all 5 authors...
Source
#1Giulia Angelini (CUA: The Catholic University of America)H-Index: 3
#2L Castagneto Gissey (Sapienza University of Rome)
Last.Giovanni Casella (Sapienza University of Rome)H-Index: 20
view all 9 authors...
Source
#1Adam Hulman (AU: Aarhus University)H-Index: 9
#2Robert Wagner (University of Tübingen)H-Index: 17
Last.Daniel R. Witte (AU: Aarhus University)H-Index: 49
view all 11 authors...
Intermediate time points during the oral glucose tolerance test (OGTT) have received more attention recently (1), with some researchers even suggesting to use 1-h glucose when screening for prediabetes (2). We demonstrated that characterization of glucose response patterns from OGTTs with five time points provides useful insights into the heterogeneity of type 2 diabetes development (3). Although such analyses are feasible in small pathophysiological investigations, they are not common in large ...
1 CitationsSource
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