Massimo Primignani
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
CirrhosisDiabetes mellitusGeneral surgeryMedicineGastroenterology
What is this?
Publications 215
The association of endoscopic variceal treatment (EVT) with the development of portal venous system thrombosis (PVST) in liver cirrhosis remains uncertain. A systematic review and meta-analysis aimed to investigate the incidence of PVST after EVT and to explore the association of EVT with the development of PVST in liver cirrhosis. All relevant studies were searched via the PubMed, EMBASE, and Cochrane Library databases. The incidence of PVST in patients treated with and without EVT was pooled. ...
#1M. Giunta (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 5
#2Vincenzo La Mura (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 17
Last. Pietro Lampertico (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 43
view all 11 authors...
Abstract The reference standard for assessing transjugular intrahepatic portosystemic shunt (TIPS) function is venography with portosystemic pressure gradient (PPG) measurement. This procedure is invasive and expensive; thus, we assessed the feasibility, reproducibility and diagnostic accuracy of color-Doppler ultrasound (CDUS) and spleen and liver stiffness (LS) measurements for identifying TIPS dysfunction. Twenty-four patients (15 undergoing TIPS placement and nine undergoing TIPS revision) c...
#1Niccolò BittoH-Index: 2
#2Giulia TosettiH-Index: 6
Last. Massimo PrimignaniH-Index: 35
view all 4 authors...
We read with interest the paper from Scheiner et al., who investigated the influence of AB0 blood group on the risk of portal vein thrombosis (PVT) in patients with cirrhosis and wish to make comments. In the general population, the venous thrombosis risk is 2-4 fold increased in non-0 individuals, likely because of their higher von Willebrand factor (VWF) and factor VIII (FVIII) levels. In cirrhotics, VWF and FVIII are markedly increased.
1 CitationsSource
#1Jonel TrebickaH-Index: 45
#2W. Gu (Goethe University Frankfurt)H-Index: 1
Last. Cándido VillanuevaH-Index: 12
view all 62 authors...
ABSTRACT Background and aims The relationship between acute-on-chronic liver failure (ACLF) and acute variceal bleeding (AVB) is poorly understood. Specifically, prevalence and prognosis of ACLF in AVB is unclear, while the role of transjugular intrahepatic porto-systemic shunt (TIPS) in the management in ACLF patients has not been described to date. Methods A multicenter, international, observational study was conducted including 2138 patients from 34 centers between 2011 and 2015. ACLF was def...
1 CitationsSource
#1Massimo PrimignaniH-Index: 35
#2Giulia TosettiH-Index: 6
Last. Armando TripodiH-Index: 51
view all 3 authors...
We read with interest the article by Kumar et al(1) and wish to make comments. A TEG-guided transfusion policy [with arbitrary thresholds of r>10min for fresh frozen plasma (FFP) and maximal amplitude (MA) 1.8 and/or platelet count <50x10(9) /L.
#1Xiangbo Xu (SPU: Shenyang Pharmaceutical University)H-Index: 1
#2Shixue Xu (Shenyang)H-Index: 1
Last. Xingshun Qi (Shenyang)H-Index: 30
view all 9 authors...
Occlusive portal venous system thrombosis (PVT) is significantly associated with poor outcomes in cirrhotic patients. Nonselective β-blockers (NSBBs) may be associated with the development of PVT. However, the role of NSBBs in progressing thrombosis remains unclear. Forty-three patients on whom contrast-enhanced computed tomography or magnetic resonance imaging was performed twice, and for whom there was detailed information regarding NSBBs, were eligible in this study, including 16 in the NSBBs...
1 CitationsSource
: Colorectal cancer (CRC) screening programs help diagnose cancer precursors and early cancers and help reduce CRC mortality. However, currently recommended tests, the fecal immunochemical test (FIT) and colonoscopy, have low uptake. There is therefore a pressing need for screening strategies that are minimally invasive and consequently more acceptable to patients, most likely blood based, to increase early CRC identification. MicroRNAs (miRNAs) released from cancer cells are detectable in plasm...
2 CitationsSource
#1Anna Baiges (University of Barcelona)H-Index: 8
#2Fanny Turon (University of Barcelona)H-Index: 18
Last. Juan Carlos García-Pagán (University of Barcelona)H-Index: 79
view all 48 authors...
Congenital extrahepatic portosystemic shunt (CEPS) or Abernethy malformation is a rare condition in which splanchnic venous blood bypasses the liver draining directly into systemic circulation through a congenital shunt. Patients may develop hepatic encephalopathy (HE), pulmonary hypertension (PaHT), or liver tumors, among other complications. However, the actual incidence of such complications is unknown, mainly because of the lack of a protocolized approach to these patients. This study charac...
#1Niccolò BittoH-Index: 2
#2Giulia TosettiH-Index: 6
Last. Vincenzo La MuraH-Index: 17
view all 10 authors...
#1Emanuela Sant'Antonio (UNISI: University of Siena)
#1Emanuela Sant'Antonio (UNISI: University of Siena)H-Index: 11
Last. Alessandro M. VannucchiH-Index: 76
view all 35 authors...
Myeloproliferative Neoplasms (MPN) course can be complicated by thrombosis involving unusual sites as the splanchnic veins (SVT). Their management is challenging, given their composite vascular risk. We performed a retrospective, cohort study in the framework of the International Working Group for MPN Research and Treatment (IWG-MRT), and AIRC-Gruppo Italiano Malattie Mieloproliferative (AGIMM). A total of 518 MPN-SVT cases were collected and compared with 1628 unselected, control MPN population...
1 CitationsSource