Rachel L. Batterham
University College London
EndocrinologyWeight lossDiabetes mellitusMedicineAppetite
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Publications 155
#1Michail KatsoulisH-Index: 15
#2Bianca DeStavola (UCL: University College London)H-Index: 10
Last. Spiros DenaxasH-Index: 23
view all 15 authors...
Background: Cross sectional measures of body mass index (BMI) are associated with cardiovascular disease (CVD) incidence, but less is known about whether weight change affects the risk of CVD. Methods: We estimated the effect of 2 year weight change interventions on 7 year risk of CVD, by emulating hypothetical target trials using electronic health records. We identified 138.567 individuals in England between 1998 and 2016, aged 45-69 years old, free of chronic diseases at baseline. We performed...
#1Francesco Rubino (University of Cambridge)H-Index: 33
#2Ricardo CohenH-Index: 16
Last. Rachel L. Batterham (UCL: University College London)H-Index: 39
view all 23 authors...
Summary The coronavirus disease 2019 pandemic is wreaking havoc on society, especially health-care systems, including disrupting bariatric and metabolic surgery. The current limitations on accessibility to non-urgent care undermine postoperative monitoring of patients who have undergone such operations. Furthermore, like most elective surgery, new bariatric and metabolic procedures are being postponed worldwide during the pandemic. When the outbreak abates, a backlog of people seeking these oper...
1 CitationsSource
#1Nicola Di Lorenzo (University of Rome Tor Vergata)H-Index: 14
#2Stavros A. Antoniou (UCY: University of Cyprus)H-Index: 1
Last. Carmil AzranH-Index: 2
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BACKGROUND: Surgery for obesity and metabolic diseases has been evolved in the light of new scientific evidence, long-term outcomes and accumulated experience. EAES has sponsored an update of previous guidelines on bariatric surgery. METHODS: A multidisciplinary group of bariatric surgeons, obesity physicians, nutritional experts, psychologists, anesthetists and a patient representative comprised the guideline development panel. Development and reporting conformed to GRADE guidelines and AGREE I...
1 CitationsSource
#1Priska StahelH-Index: 4
Last. Allan OkrainecH-Index: 26
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In the article cited above, affiliations for the authors below were listed incorrectly. The correct affiliations are given here. Timothy Jackson: Division of General Surgery, University Health Network, Toronto, Ontario, Canada, and Bariatric Surgery Department, Toronto Western Hospital, Toronto, Ontario, Canada David R. Urbach: Bariatric Surgery Department, Toronto Western Hospital, Toronto, Ontario, Canada Allan Okrainec: Division of General Surgery, University Health Network, Toronto, Ontario,...
#1Francesco Rubino (University of Cambridge)H-Index: 33
#2Rebecca M. Puhl (UConn: University of Connecticut)H-Index: 45
Last. Douglas Twenefour (Diabetes UK)H-Index: 1
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People with obesity commonly face a pervasive, resilient form of social stigma. They are often subject to discrimination in the workplace as well as in educational and healthcare settings. Research indicates that weight stigma can cause physical and psychological harm, and that affected individuals are less likely to receive adequate care. For these reasons, weight stigma damages health, undermines human and social rights, and is unacceptable in modern societies. To inform healthcare professiona...
13 CitationsSource
#1Roger Williams (Foundation for Liver Research)H-Index: 7
#1Roger Williams (Foundation for Liver Research)H-Index: 135
Last. Andrew Yeoman (Aneurin Bevan University Health Board)H-Index: 4
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Summary This final report of the Lancet Commission into liver disease in the UK stresses the continuing increase in burden of liver disease from excess alcohol consumption and obesity, with high levels of hospital admissions which are worsening in deprived areas. Only with comprehensive food and alcohol strategies based on fiscal and regulatory measures (including a minimum unit price for alcohol, the alcohol duty escalator, and an extension of the sugar levy on food content) can the disease bur...
#1Janine M. Makaronidis (UCL: University College London)H-Index: 6
#2Rachel L. Batterham (UCL: University College London)H-Index: 39
The growing obesity epidemic is driving the need for the development of novel, effective therapeutic strategies for obesity and its complications. Increasing our understanding of the processes controlling body weight is therefore imperative. Gut hormones have emerged as essential regulators of energy homeostasis. Dysregulation of gut hormone physiology is increasingly implicated in obesity pathogenesis and the compensatory biological responses driving weight regain following energy restriction. ...
#1Priska Stahel (U of T: University of Toronto)H-Index: 4
#2Avital Nahmias (U of T: University of Toronto)
Last. Satya Dash (U of T: University of Toronto)H-Index: 10
view all 21 authors...
Extreme obesity (EO, BMI>50) is frequently associated with neuropsychiatric disease (NPD). As both EO and NPD are heritable central nervous system disorders, we assessed the prevalence of protein truncating (PTV) and copy number variants (CNV) in genes/regions previously implicated in NPD, in adults with EO (n=149) referred for weight loss/bariatric surgery. We also assessed the prevalence of CNVs in patients referred to University College London Hospital (UCLH) with EO (n=218) and obesity (O, B...
#1James L. Dorling (Pennington Biomedical Research Center)H-Index: 3
#2David J. Clayton (NTU: Nottingham Trent University)H-Index: 9
Last. David J. Stensel (National Health Service)H-Index: 27
view all 9 authors...
Background: The fat mass and obesity-associated gene (FTO) rs9939609 A-allele is associated with higher acyl-ghrelin (AG) concentrations, higher energy intake and obesity, though exercise may mitigate rs9939609 A-allele linked obesity risk. Butyrylcholinesterase (BChE) hydrolyses AG to des-acyl-ghrelin (DAG), potentially decreasing appetite. However, the effects of the FTO rs9939609 genotype and exercise on BChE activity, AG, DAG and energy intake are unknown. Objective: We hypothesized that ind...
1 CitationsSource
#1Luís Crisóstomo (University of Porto)H-Index: 1
#2Luís RatoH-Index: 17
Last. Marco G. Alves (University of Porto)H-Index: 28
view all 8 authors...