Peter J. Joris
Maastricht University Medical Centre
EndocrinologyPostprandialWeight lossDiabetes mellitusMedicine
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Publications 31
#1Lea Tischmann (Maastricht University Medical Centre)H-Index: 3
#2Mathijs Drummen (Maastricht University Medical Centre)H-Index: 1
Last. Margriet S. Westerterp-Plantenga (Maastricht University Medical Centre)H-Index: 70
view all 11 authors...
An unfavorable lipid profile and being overweight are known mediators in the development of cardiovascular disease (CVD) risk. The effect of diet, particularly high in protein, remains under discussion. Therefore, this study examines the effects of a high-protein (HP) diet on cardiometabolic health and vascular function (i.e., endothelial function, arterial stiffness, and retinal microvascular structure), and the possible association with plasma endocannabinoids and endocannabinoid-related compo...
#1Gerard Rietjens (MOD: United Kingdom Ministry of Defence)H-Index: 1
Last. Guy Plasqui (Maastricht University Medical Centre)H-Index: 22
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The present study was designed to objectively assess the effects of 3-months submarine deployment on behavioural and metabolic determinants of metabolic health. In 13 healthy, non-obese volunteers, we using stable isotope dilution, and plasma and urinary biochemistry to characterize metabolic health before and after a 3-month submarine deployment. Volunteers worked in 6-h shifts. After deployment, we observed reduced fat-free mass (mean ± SD, −4.1 ± 3.3 kg, p = 0.003) and increased adiposity (21...
#1Peter J. Joris (UM: Maastricht University)H-Index: 8
#2Jogchum Plat (UM: Maastricht University)H-Index: 41
Last. Ronald P. Mensink (UM: Maastricht University)H-Index: 62
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Summary Background Effects of weight loss on postprandial vascular function have not been studied so far. We therefore examined (i) effects of diet-induced weight loss on postprandial changes in various vascular function markers after consumption of a mixed meal and (ii) differences between normal-weight and abdominally obese men of comparable age at baseline and after weight loss. Methods Fifty-four apparently healthy abdominally obese (waist circumference: 102-110 cm) and 25 normal-weight men ...
#1Jordi P. D. Kleinloog (UM: Maastricht University)H-Index: 1
#2Ronald P. Mensink (UM: Maastricht University)H-Index: 62
Last. Peter J. Joris (UM: Maastricht University)H-Index: 8
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Background Physical activity may attenuate age-related cognitive decline by improving cerebrovascular function. The aim of this study was therefore to investigate effects of aerobic exercise training on cerebral blood flow (CBF), which is a sensitive physiological marker of cerebrovascular function, in sedentary older men. Methods Seventeen apparently healthy men, aged 60-70 years and with a BMI between 25 and 35 kg/m2, were included in a randomized, controlled cross-over trial. Study participan...
3 CitationsSource
#1Peter J. Joris (UM: Maastricht University)H-Index: 8
#2Richard DraijerH-Index: 21
Last. Ronald P. Mensink (UM: Maastricht University)H-Index: 62
view all 4 authors...
Abstract Background Only a limited number of studies have examined the vascular and postprandial effects of α-linolenic acid (ALA, C18:3n-3). Therefore, we performed a well-controlled trial focussing specifically on the effects of ALA on vascular function and metabolic risk markers during the fasting and postprandial phase in untreated (pre-)hypertensive individuals. Methods In a double-blind randomized, placebo-controlled parallel study, 59 overweight and obese adults (40 men and 19 women, aged...
#1Lea Tischmann (Maastricht University Medical Centre)H-Index: 3
#2Mathijs Drummen (Maastricht University Medical Centre)H-Index: 6
Last. Tanja C. AdamH-Index: 20
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Favorable effects of a high-protein/moderate-carbohydrate (HP/MCHO) diet after weight loss on body weight management have been shown. To extend these findings, associations between perception of hunger and satiety with endocannabinoids, and with glucagon-like peptide-1 (GLP-1) and polypeptide YY (PYY) were assessed. At approximately 34 months after weight loss, 22 female and 16 male participants (mean age 64.5 ± 5.9 years; body mass index (BMI) 28.9 ± 3.9 kg/m2) completed a 48 h respiration cham...
6 CitationsSource
#1Lea Tischmann (UM: Maastricht University)H-Index: 3
#2Mathijs Drummen (UM: Maastricht University)H-Index: 6
Last. Tanja C. Adam (UM: Maastricht University)H-Index: 20
view all 8 authors...
#1Peter J. JorisH-Index: 8
Last. Ronald P. MensinkH-Index: 62
view all 4 authors...
#1Ine Telgenkamp (UM: Maastricht University)H-Index: 1
#2Yvo H.A.M. Kusters (UM: Maastricht University)H-Index: 4
Last. Martijn C. G. J. Brouwers (UM: Maastricht University)H-Index: 18
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CONTEXT: Hepatokines have emerged as potential mediators of obesity-associated comorbidities, such as type 2 diabetes, cardiovascular disease, fractures, and central hypogonadism. OBJECTIVE: To assess whether weight loss-induced changes in hepatokines are mediated by intrahepatic triglyceride (IHTG) content. DESIGN: Cross-sectional study and randomized controlled trial. SETTING: General community. PARTICIPANTS: Metabolically healthy, lean men (waist <94 cm; n = 25) and men with abdominal obesity...
1 CitationsSource
#1Joëlle C. Schutten (UMCG: University Medical Center Groningen)H-Index: 3
#2Peter J. Joris (UM: Maastricht University)H-Index: 8
Last. Stephan J. L. Bakker (UMCG: University Medical Center Groningen)H-Index: 70
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Background Arterial stiffness is closely related to the process of atherosclerosis, an independent cardiovascular risk factor, and predictive of future cardiovascular events and mortality. Recently, we showed that magnesium citrate supplementation results in a clinically relevant improvement of arterial stiffness. It remained unclear whether the observed effect was due to magnesium or citrate, and whether other magnesium compounds may have similar effects. Therefore, we aim to study the long-ter...
1 CitationsSource