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Esther Ciarrocchi
University of Pisa
18Publications
4H-index
40Citations
Publications 18
Newest
#1S.M. Valle (INFN: Istituto Nazionale di Fisica Nucleare)
#2A. AlexandrovH-Index: 6
Last.Antonio Zoccoli (UNIBO: University of Bologna)H-Index: 85
view all 69 authors...
Abstract Particle therapy uses proton or 12 C beams to treat deep-seated solid tumors. Due to the advantageous characteristics of charged particles energy deposition in matter, the maximum of the dose is released to the tumor at the end of the beam range, in the Bragg peak region. However, the beam nuclear interactions with the patient tissues induces fragmentation both of projectile and target nuclei and needs to be carefully taken into account. In proton treatments, the target fragmentation pr...
#1Esther Ciarrocchi (UniPi: University of Pisa)H-Index: 4
#2Nicola Belcari (UniPi: University of Pisa)H-Index: 21
Last.Maria Giuseppina Bisogni (UniPi: University of Pisa)H-Index: 18
view all 14 authors...
Abstract The FOOT experiment aims at identifying the fragments produced in the human body during hadrontherapy and at measuring their cross sections. The apparatus is composed of several detectors which allow a complete reconstruction of the tracks of the fragments. In particular, the Δ E-TOF detector measures the energy released in a thin plastic scintillator and the time of flight of the fragments. In this work, we report the energy and time resolution of a Δ E-TOF detector prototype with prot...
#1Matteo Morrocchi (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 10
#2Esther Ciarrocchi (UniPi: University of Pisa)H-Index: 4
Last.Maria Giuseppina Bisogni (UniPi: University of Pisa)H-Index: 18
view all 95 authors...
Abstract This paper describes the development and characterization of a Δ E-TOF detector composed of a plastic scintillator bar coupled at both ends to silicon photomultipliers. This detector is a prototype of a larger version which will be used in the FOOT (FragmentatiOn Of Target) experiment to identify the fragments produced by ion beams accelerated onto a hydrogen-enriched target. The final Δ E-TOF detector will be composed of two layers of plastic scintillator bars with orthogonal orientati...
#1Esther Ciarrocchi (UniPi: University of Pisa)H-Index: 4
#2Christian Vanhove (UGent: Ghent University)H-Index: 27
Last.Nicola Belcari (UniPi: University of Pisa)H-Index: 21
view all 6 authors...
Abstract The performances of an intra-operative optical imaging system for Cerenkov luminescence imaging of resected tumor specimens were evaluated with phantom studies. The spatial resolution, the linearity of the measured signal with the activity concentration and the minimum detectable activity concentration were considered. A high linearity was observed over a broad range of activity concentration ( R 2 ⩾ 0.99 down to ∼40 kBq/ml of 18F-FDG). For 18F-FDG activity distributions 2 mm deep in bi...
#1S.M. ValleH-Index: 1
#2Silvia BiondiH-Index: 44
Last.Matteo MorrocchiH-Index: 10
view all 90 authors...
#1Esther Ciarrocchi (UniPi: University of Pisa)H-Index: 4
#2Nicola Belcari (UniPi: University of Pisa)H-Index: 21
Cerenkov luminescence imaging (CLI) is a novel imaging modality to study charged particles with optical methods by detecting the Cerenkov luminescence produced in tissue. This paper first describes the physical processes that govern the production and transport in tissue of Cerenkov luminescence. The detectors used for CLI and their most relevant specifications to optimize the acquisition of the Cerenkov signal are then presented, and CLI is compared with the other optical imaging modalities sha...
#1Giuseppe BattistoniH-Index: 13
#2A. AlexandrovH-Index: 5
Last.Antonio ZoccoliH-Index: 85
view all 68 authors...
Particle therapy uses proton or 12C beams for the treatment of deep-seated solid tumors. Due to the features of energy deposition of charged particles a small amount of dose is released to the healthy tissue in the beam entrance region, while the maximum of the dose is released to the tumor at the end of the beam range, in the Bragg peak region. However nuclear interactions between beam and patient tissues induce fragmentation both of projectile and target and must be carefully taken into accoun...
#1Esther Ciarrocchi (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 4
#2N. Belcari (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 7
Last.Alberto Del Guerra (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 31
view all 5 authors...
Cerenkov luminescence imaging (CLI) is an optical imaging modality recently proposed to image β emitting radionuclides through the Cerenkov light they produce in tissue. CLI has been suggested in particular for β− emitting isotopes, which are difficult to study by other means, and as a cost-effective alternative to PET, yet with reduced penetration depth and spatial resolution. In this work we tested the predictive capabilities of a Monte Carlo model developed within the Geant4 platform for the ...
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