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Ulla Vogel
Technical University of Denmark
399Publications
60H-index
12.5kCitations
Publications 398
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#1Maria Helena Guerra Andersen (UCPH: University of Copenhagen)H-Index: 6
#2Marie FrederiksenH-Index: 16
Last.Ulla Vogel (DTU: Technical University of Denmark)H-Index: 60
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Short-term controlled exposure to diesel exhaust (DE) in chamber studies have shown mixed results on lung and systemic effects. There is a paucity of studies on well-characterized real-life DE exposure in humans. In the present study, 29 healthy volunteers were exposed to DE while sitting as passengers in diesel-powered trains. Exposure in electric trains was used as control scenario. Each train scenario consisted of three consecutive days (6 h/day) ending with biomarker samplings. Combustion-de...
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#1Niels HadrupH-Index: 16
Last.Ulla VogelH-Index: 60
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Background Coke oven workers are exposed to both free and particle bound PAH. Through this exposure, the workers may be at increased risk of cardiovascular diseases. Systemic levels of acute phase response proteins have been linked to cardiovascular disease in epidemiological studies, suggesting it as a marker of these conditions. The aim of this study was to assess whether there was association between PAH exposure and the blood level of the acute phase inflammatory response marker serum amyloi...
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#2Anders Brostrøm (DTU: Technical University of Denmark)H-Index: 1
Last.Ulla Vogel (DTU: Technical University of Denmark)H-Index: 60
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Little is known about the exposure levels and adverse health effects of occupational exposure to airplane emissions. Diesel exhaust particles are classified as carcinogenic to humans and jet engines produce potentially similar soot particles. Here, we evaluated the potential occupational exposure risk by analyzing particles from a non-commercial airfield and from the apron of a commercial airport. Toxicity of the collected particles was evaluated alongside NIST standard reference diesel exhaust ...
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#1Anna Jacobsen Lauvås (UCPH: University of Copenhagen)H-Index: 1
#2Astrid Skovmand (UCPH: University of Copenhagen)H-Index: 4
Last.Karin Sørig Hougaard (UCPH: University of Copenhagen)H-Index: 29
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Abstract Several types of engineered nanoparticles (ENP) have been shown to adversely affect male reproduction in rodent studies, but the airway route of exposure has been little investigated. This precludes adequate risk assessment of ENP exposure in occupational settings. Titanium dioxide nanoparticles (TiO2 NP) have been shown to affect total sperm count in adult male mice after intravenous and oral administration. This study aimed to investigate whether also airway exposure would affect sper...
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#1Astrid Skovmand (UCPH: University of Copenhagen)H-Index: 4
Last.Karin Sørig Hougaard (UCPH: University of Copenhagen)H-Index: 29
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Previous findings indicate that in utero exposure to nanoparticles may affect the reproductive system in male offspring. Effects such as decreased sperm counts and testicular structural changes in F1 males have been reported following maternal airway exposure to carbon black during gestation. In addition, a previous study in our laboratory suggested that the effects of in utero exposure of nanoparticles may span further than the first generation, as sperm content per gram of testis was significa...
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#1Niels HadrupH-Index: 16
#2Feriel Rahmani (Health Canada)
Last.Ulla Vogel (DTU: Technical University of Denmark)H-Index: 60
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AbstractInhalation of nanosized zinc oxide (ZnO) induces metal fume fever and systemic acute phase response in humans. Acute phase response activation is a cardiovascular risk factor; we investigat...
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#1Kenneth Klingenberg Barfod (UCPH: University of Copenhagen)H-Index: 2
Last.Ulla Vogel (DTU: Technical University of Denmark)H-Index: 60
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Abstract The toxicological potential of halloysite nanotubes (HNTs) and variants after functional alterations to surface area are not clear. We assessed the toxicological response to HNTs (NaturalNano (NN)) before and after surface etching (NN-etched). Potential cytotoxicity of the two HNTs was screened in vitro in MutaTMMouse lung epithelial cells. Lung inflammation, acute phase response and genotoxicity were assessed 1, 3, and 28 days after a single intratracheal instillation of adult female C...
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#1Laurent Gaté (Institut national de recherche et de sécurité)H-Index: 7
Last.Frédéric Cosnier (Institut national de recherche et de sécurité)H-Index: 8
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Abstract Multi-walled carbon nanotubes (MWCNTs), which vary in length, diameter, functionalization and specific surface area, are used in diverse industrial processes. Since these nanomaterials have a high aspect ratio and are biopersistant in the lung, there is a need for a rapid identification of their potential health hazard. We assessed in Sprague-Dawley rats the pulmonary toxicity of two pristine MWCNTs (the “long and thick” NM-401 and the “short and thin” NM-403) following either intratrac...
2 CitationsSource
#1Vibeke AndersenH-Index: 29
#2Ulrich HalekohH-Index: 17
Last.Tine Iskov Kopp (Rigshospitalet)H-Index: 7
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Although vitamin A is essential for gut immune cell trafficking (paramount for the intestinal immune system), epidemiological studies on the role of vitamin A in colorectal cancer (CRC) aetiology are conflicting. By using functional polymorphisms, gene–environment (GxE) interaction analyses may identify the biological effects (or “mechanism of action”) of environmental factors on CRC aetiology. Potential interactions between dietary or supplemental vitamin A intake and genetic variation in the v...
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#1Daniele Campa (UniPi: University of Pisa)H-Index: 30
#2Alessandro Martino (DKFZ: German Cancer Research Center)H-Index: 14
Last.Federico Canzian (DKFZ: German Cancer Research Center)H-Index: 59
view all 47 authors...
AbstractGenetic variants in genes acting during the maturation process of immature B-cell to differentiated plasma cell could influence the risk of developing multiple myeloma (MM). During B-cell maturation, several programmed genetic rearrangements occur to increase the variation of the immunoglobulin chains. Class switch recombination (CSR) is one of the most important among these mechanisms. Germline polymorphisms altering even subtly this process could play a role in the etiology and outcome...
1 CitationsSource
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