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Adrian L. Lopresti
Murdoch University
28Publications
10H-index
708Citations
Publications 28
Newest
#1Adrian L. Lopresti (Murdoch University)H-Index: 10
#2Stephen J. Smith (Murdoch University)
Last.Peter D. Drummond (Murdoch University)H-Index: 45
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Background:As a stand-alone intervention, saffron has efficacy for the treatment of mild-to-moderate depression. However, research as an adjunct agent is limited.Aims:The effects of saffron as an a...
Abstract Psychological and pharmacological interventions are the most common treatments for adult depression. While these interventions have robust evidence supporting their efficacy, there remain up to 60 percent of individuals who do not respond to treatment, or only partially respond. Unfortunately, efforts at improving outcome rates from new or modified versions of psychological or pharmacological interventions have been disappointing. It is argued that increased treatment efficacy for depre...
#1Adrian L. Lopresti (Murdoch University)H-Index: 10
#2Peter D. Drummond (Murdoch University)H-Index: 45
Last.Stephen J. Smith (Murdoch University)
view all 3 authors...
Ashwagandha (Withania somnifera) is a herb commonly used in Ayurvedic medicine to promote youthful vigor, enhance muscle strength and endurance, and improve overall health. In this 16-week, randomized, double-blind, placebo-controlled, crossover study, its effects on fatigue, vigor, and steroid hormones in aging men were investigated. Overweight men aged 40–70 years, with mild fatigue, were given a placebo or an ashwagandha extract (Shoden beads, delivering 21 mg of withanolide glycosides a day)...
#1Adrian L. Lopresti (Murdoch University)H-Index: 10
Abstract Increasing evidence suggests that major depressive disorder is associated with mitochondrial dysfunction, and consequently, increased oxidative stress. In this chapter, the role of mitochondria and how they potentially influence physiological processes associated with depression are reviewed. Research on mitochondrial disturbances in adults with depression is also summarized and possible causes for these disturbances are presented. In particular, a focus is placed on lifestyle, environm...
#1Adrian L. LoprestiH-Index: 10
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Background: Ashwagandha (Withania somnifera (L.) Dunal) is a herb traditionally used to reduce stress and enhance wellbeing. The aim of this study was to investigate its anxiolytic effects on adults with self-reported high stress and to examine potential mechanisms associated with its therapeutic effects. Methods: In this 60-day, randomized, double-blind, placebo-controlled study the stress-relieving and pharmacological activity of an ashwagandha extract was investigated in stressed, healthy adu...
#1Adrian L. Lopresti (Murdoch University)H-Index: 10
Last.Stephen J. Smith (SCU: Southern Cross University)
view all 3 authors...
Background To evaluate the efficacy and tolerability of a poly-herbal formulation, Herbagut, for the treatment of gastrointestinal symptoms and its effect on quality of life parameters in patients presenting with self-reported, unsatisfactory bowel habits.
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