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Kathryn L. Gatford
University of Adelaide
99Publications
22H-index
1,634Citations
Publications 99
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#1Kathryn L. Gatford (University of Adelaide)H-Index: 22
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#1Amy L. Wooldridge (University of Adelaide)H-Index: 5
#2Mark McMillan (University of Adelaide)H-Index: 9
Last.Kathryn L. Gatford (University of Adelaide)H-Index: 22
view all 6 authors...
Background Individual susceptibility to allergic diseases is developmentally programmed by early-life exposures. Evidence from preclinical studies suggests that intrauterine growth restriction is protective against later inflammatory responses to allergens. Objective We sought to evaluate whether prenatal growth affects susceptibility to allergy in human subjects. Methods We systematically searched for relevant studies in 11 databases, including Web of Science, ProQuest, EMBASE, and PubMed. We i...
Source
#1Amy L. Wooldridge (University of Adelaide)H-Index: 5
#2Vicki L. Clifton (University of Adelaide)H-Index: 41
Last.Kathryn L. Gatford (University of Adelaide)H-Index: 22
view all 12 authors...
Experimental maternal allergic asthma in sheep provides an experimental model in which to test impacts on progeny Fetuses from allergic asthmatic ewes had fewer surfactant-producing cells in lungs A greater proportion of lymphocytes from thymus were CD44 positive in fetuses from allergic asthmatic ewes than controls These changes to fetal development might contribute to poor neonatal lung function and increased risk of allergy seen in offspring of pregnancies complicated by asthma ABSTRACT: Asth...
1 CitationsSource
#1Vicki L. Clifton (Translational Research Institute)H-Index: 41
#2Megan McDonald (Translational Research Institute)
Last.Timothy J. M. Moss (Monash University, Clayton campus)H-Index: 44
view all 13 authors...
Abstract Maternal asthma increases the risk of adverse pregnancy outcomes and may affect fetal growth and placental function by differential effects on the expression of glucocorticoid receptor (GR) isoforms, leading to altered glucocorticoid signalling. Our aim was to examine the effect of maternal asthma on placental GR profiles using a pregnant sheep model of asthma. Nine known GR isoforms were detected. There was a significant increase in the expression of placental GR isoforms that are know...
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#1Tamara J. Varcoe (UniSA: University of South Australia)H-Index: 16
#2Jack R. T. Darby (UniSA: University of South Australia)H-Index: 4
Last.Janna L. Morrison (UniSA: University of South Australia)H-Index: 34
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1 CitationsSource
#1Kathryn L. Gatford (University of Adelaide)H-Index: 22
#2David J. Kennaway (University of Adelaide)H-Index: 39
Last.Tamara J. Varcoe (University of Adelaide)H-Index: 16
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Kathryn L. Gatford, David J. Kennaway, Hong Liu, David O. Kleemann, Timothy R Kuchel, Tamara J. Varcoe
1 CitationsSource
#1Dane M. Horton (University of Adelaide)H-Index: 2
#2David A. Saint (University of Adelaide)H-Index: 32
Last.Julie A. Owens (University of Adelaide)H-Index: 52
view all 5 authors...
Intrauterine growth restriction (IUGR) and subsequent neonatal catch-up growth are implicated in programming of insulin resistance later in life. Spontaneous IUGR in the guinea pig, due to natural ...
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#1Harleen Kaur (University of Adelaide)
#2Rebecca L. Wilson (University of Adelaide)H-Index: 4
Last.Kathryn L. Gatford (University of Adelaide)H-Index: 22
view all 6 authors...
Abstract Introduction Proper placental function is essential for optimal fetal growth in utero. Placental transfer of nutrients to the fetus can be measured using radiolabelled tracers, but non-radioactive methods have potential advantages. This study aimed to develop a fluorescence-based method to measure placental glucose transport in mice. Methods Time course and localisation of the IRDye 800CW 2-deoxyglucose were recorded (Lumina IVIS Live Imaging System) following tail vein injection into a...
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#1Kathryn L. Gatford (University of Adelaide)H-Index: 22
1 CitationsSource
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