Sei Hyun Baik
Korea University
Publications 212
#1Kyoung Jin Kim (KU: Korea University)H-Index: 1
#2Jimi Choi (KU: Korea University)
Last.Kyung Mook Choi (KU: Korea University)H-Index: 46
view all 13 authors...
Background To determine the impact of dipeptidyl peptidase-4 inhibitor (DPP4i) on the risk of major cardiocerebrovascular and renal outcomes compared with sulfonylurea (SU) combined with metformin in patients with type 2 diabetes from a population-based cohort.
#1Jung A. Kim (KU: Korea University)H-Index: 2
#2Eun Roh (KU: Korea University)H-Index: 2
Last.Sei Hyun Baik (KU: Korea University)H-Index: 35
view all 11 authors...
Abstract Background Sclerostin is an osteocyte-derived circulating protein that inhibits the Wnt/β-catenin signaling pathway. The Wnt signaling pathway plays an important role in bone and dysregulation of the Wnt signaling pathway results in insulin resistance, inflammation, and metabolic disturbance. The aim of our study was to investigate the implication of sclerostin in low muscle mass in healthy subjects. Methods The cross-sectional study analyzed 240 healthy non-diabetic subjects from the K...
#1So-hyeon Hong (KU: Korea University)H-Index: 1
#2Hwan-Jin Hwang (KU: Korea University)H-Index: 8
Last.Hye Jin Yoo (KU: Korea University)H-Index: 32
view all 9 authors...
Abstract Background Ginsenoside compound-Mc1 (Mc1) is a member of the de-glycosylated ginsenosides obtained from ginseng extract. Although several ginsenosides have a cardioprotective effect, this has not been demonstrated in ginsenoside Mc1. Methods We treated H9c2 cells with hydrogen peroxide (H2O2) and ginsenoside Mc1 to evaluate the antioxidant effects of Mc1. The levels of antioxidant molecules, catalase and superoxide dismutase 2 (SOD2), were measured, and cell viability was determined usi...
#1Hye Soo ChungH-Index: 5
#2Ji Sung LeeH-Index: 16
Last.Ji A SeoH-Index: 34
view all 13 authors...
Although it has been suggested that the γ-glutamyltransferase (GGT) level is an indicator of cardiometabolic disorders, there is no previous study to evaluate the implication of GGT variability on the development of myocardial infarction (MI), stroke, all-cause mortality, and cardiovascular disease (CVD)-related mortality. GGT variability was measured as the coefficient variance (GGT-CV), standard deviation (GGT-SD), and variability independent of the mean (GGT-VIM). Using the population-based K...
#1Hye Soo ChungH-Index: 5
#2Hye Soo Chung (Hallym University)H-Index: 1
Last.Hye Jin YooH-Index: 32
view all 13 authors...
Introduction: Although total cholesterol (TC) variability suggested for a risk factor for cardiovascular and cerebrovascular disease, there was no previous study to evaluate the association between TC variability and the development of dementia. Methods: Using the Korean National Health Insurance Service–Health Screening Cohort (NHIS-HEALS), the main outcomes were newly diagnosed all-cause dementia, Alzheimer’s disease (AD), or vascular dementia (VaD) between January 1, 2008, and December 31, 20...