Match!
Daisuke Sato
Shiga University of Medical Science
10Publications
4H-index
48Citations
Publications 10
Newest
#1Daisuke Sato (Shiga University of Medical Science)H-Index: 4
#2Katsutaro Morino (Shiga University of Medical Science)H-Index: 26
Last.Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 8 authors...
Source
#1Takuya Okamoto (Shiga University of Medical Science)H-Index: 1
#2Katsutaro Morino (Shiga University of Medical Science)H-Index: 26
Last.Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 10 authors...
The intestinal microbiome produces short-chain fatty acids (SCFAs) from dietary fiber and has specific effects on other organs. During endurance exercise, fatty acids, glucose, and amino acids are ...
1 CitationsSource
#1Satoshi Ugi (Shiga University of Medical Science)H-Index: 26
#2Katsutaro Morino (Shiga University of Medical Science)H-Index: 26
Last.Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 12 authors...
Source
#1Hideka InoueH-Index: 1
#2Katsutaro MorinoH-Index: 26
Last.Hiroshi MaegawaH-Index: 48
view all 16 authors...
3 CitationsSource
#1Mengistu Lemecha (Shiga University of Medical Science)H-Index: 3
#2Katsutaro Morino (Shiga University of Medical Science)H-Index: 26
Last.Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 10 authors...
Mitochondria are critical in heat generation in brown and beige adipocytes. Mitochondrial number and function are regulated in response to external stimuli, such as cold exposure and β3 adrenergic receptor agonist. However, the molecular mechanisms regulating mitochondrial biogenesis during browning, especially by microRNAs, remain unknown. We investigated the role of miR-494-3p in mitochondrial biogenesis during adipogenesis and browning. Intermittent mild cold exposure of mice induced PPARγ co...
4 CitationsSource
#1Katsutaro MorinoH-Index: 26
#2Hideka InoueH-Index: 1
Last.Hiroshi MaegawaH-Index: 48
view all 14 authors...
Objective: Weight gain is a common problem in the insulin treatment. SGLT2 inhibitors are expected to reduce body weight (BW) due to negative energy balance. Previous reports suggested that BW reduction is achieved mainly by loss of body fat, and ∼20% of reduction is by lean mass. However, the efficacy of SGLT2 inhibitor on BW and body composition remains unclear. We examined these in the Japanese T2DM treated with insulin. Methods: The study was an open label randomized controlled trial. Primar...
Source
Postprandial hypertriglyceridemia is a potential target for cardiovascular disease prevention in patients with diabetic dyslipidemia. Metformin has been reported to reduce plasma triglyceride concentrations in the postprandial states. However, little is known about the mechanisms underlying the triglyceride-lowering effect of metformin. Here, we examined the effects of metformin on lipid metabolism after olive oil-loading in 129S mice fed a high fat diet for three weeks. Metformin administration...
6 CitationsSource
#1Kohji Nagayama (Shiga University of Medical Science)H-Index: 1
#2Katsutaro Morino (Shiga University of Medical Science)H-Index: 26
Last.Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 15 authors...
N-3 polyunsaturated fatty acids such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have protective effects against atherosclerosis. Monocyte chemotactic protein (MCP)-1 is a major inflammatory mediator in the progression of atherosclerosis. However, little is known about the regulation of MCP-1 by DHA and EPA in vessels and vascular smooth muscle cells (VSMCs). In this study, we compared the effect of DHA and EPA on the expression of Mcp-1 in rat arterial strips and rat VSMCs. DH...
5 CitationsSource
#1Fumiyuki Nakagawa (Shiga University of Medical Science)H-Index: 7
#2Katsutaro Morino (Shiga University of Medical Science)H-Index: 26
Last.Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 15 authors...
Abstract It has recently been reported that expression of heme oxygenase-1 (HO-1) plays a protective role against many diseases. Furthermore, n-3 polyunsaturated fatty acids (PUFAs) were shown to induce HO-1 expression in several cells in vitro, and in a few cases also in vivo. However, very few reports have demonstrated that n-3 PUFAs induce HO-1 in vivo. In this study, we examined the effect of fish-oil dietary supplementation on the distribution of fatty acids and their peroxidative metabolit...
21 CitationsSource
#1Daisuke Sato (Shiga University of Medical Science)H-Index: 4
#2Katsutaro Morino (Shiga University of Medical Science)H-Index: 26
Last.Hiroshi Maegawa (Shiga University of Medical Science)H-Index: 48
view all 10 authors...
Dumping syndrome, or rapid gastric emptying, is a frequent complication after gastric surgery. In this case, the patient was a 47-year-old woman who 10 years previously had undergone distal gastrectomy with Billroth I reconstruction for early-stage gastric cancer. She presented with symptoms of weakness, headache, palpitation, sweating, dizziness and significant fatigue between one and two hours after a meal. Because a 75g oral glucose tolerance test (75g-OGTT) induced both acute postprandial ta...
8 CitationsSource
1