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Roberta Messina
Vita-Salute San Raffaele University
Physical therapyMigraineAtrophyWhite matterMedicine
47Publications
9H-index
335Citations
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Publications 48
Newest
#1Roberta MessinaH-Index: 9
#2Massimo Filippi (UniSR: Vita-Salute San Raffaele University)H-Index: 118
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#1Roberta MessinaH-Index: 9
#2Maria A. RoccaH-Index: 71
Last. Massimo FilippiH-Index: 118
view all 7 authors...
Resting state (RS) functional connectivity (FC) abnormalities of brain networks involved in pain- and multisensory processing have been disclosed in adult-migraine patients. We explored RS FC of large-scale brain networks in pediatric-migraine patients and their correlation with patients’ clinical characteristics. RS functional MRI data was acquired from 13 pediatric-migraine patients and 14 age- and sex-matched controls. Intra- and inter-network RS FC differences between patients and controls w...
Source
Chronic migraine is a highly disabling disease with a great impact on socioeconomic functioning and quality of life of migraine patients. Chronic migraine usually evolves from episodic migraine that gradually increases in attack frequency, supporting the view of migraine as a spectrum disorder. Pathophysiological mechanisms responsible for migraine chronification are not fully understood. Likewise episodic migraine, chronic migraine patients showed widespread functional and structural alteration...
Source
#1Massimo FilippiH-Index: 5
#1M FilippiH-Index: 5
Last. Maria A. RoccaH-Index: 71
view all 4 authors...
#1Bruno Colombo (UniSR: Vita-Salute San Raffaele University)H-Index: 45
#2Roberta Messina (UniSR: Vita-Salute San Raffaele University)H-Index: 9
Last. Massimo Filippi (UniSR: Vita-Salute San Raffaele University)H-Index: 118
view all 4 authors...
In the last 20 years, we observed significant improvements in the use of magnetic resonance imaging (MRI) for the evaluation of patients affected by migraine. Before these technological advances, knowledge of the pathogenesis of migraine was particularly based on clinical assessment. Complementary to clinical evaluation, conventional MRI provides both specific information for differential diagnosis (particularly if cortical or subcortical lesions are detected in the migrainous brain) and unsurpa...
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#1Massimo FilippiH-Index: 118
#2Roberta MessinaH-Index: 9
Last. Maria A. RoccaH-Index: 71
view all 4 authors...
We thank Dr. Gupta for his interest in our study.1 We agree that many variables can confound volumetric measurements and more effort is needed to minimize these factors in neuroimaging studies. Although migraine is one of the most common neurologic diseases, the number of patients with migraine enrolled in MRI studies remains relatively low (on average, around 20). Only a few studies succeeded in including a larger sample of patients.2
Source
#1Marzia Romeo (UniSR: Vita-Salute San Raffaele University)H-Index: 7
#2Vittorio MartinelliH-Index: 44
Last. Giancarlo Comi (UniSR: Vita-Salute San Raffaele University)H-Index: 90
view all 23 authors...
1 CitationsSource
#1Roberta Messina (UniSR: Vita-Salute San Raffaele University)H-Index: 9
#2Massimo Filippi (UniSR: Vita-Salute San Raffaele University)H-Index: 118
Last. Peter J. GoadsbyH-Index: 111
view all 3 authors...
Purpose of reviewPrimary headaches, such as migraine and cluster headache, are one of the most common and disabling neurological diseases worldwide. Neuroimaging studies have changed the way we understand these diseases and have enriched our knowledge of the mechanisms of actions of currently availa
2 CitationsSource
#1Roberta MessinaH-Index: 9
#2Maria A. RoccaH-Index: 71
Last. Massimo FilippiH-Index: 118
view all 7 authors...
Objective To explore cross-sectional and longitudinal gray matter (GM) volume changes in patients with migraine and their association with patients9 clinical characteristics and disease activity. Methods Brain T2-weighted and 3-dimensional T1-weighted scans were acquired from 73 episodic migraineurs and 46 age- and sex-matched nonmigraine controls at baseline. Twenty-four migraineurs and 25 controls agreed to be reexamined after a mean follow-up of 4 years. Using a general linear model and SPM12...
8 CitationsSource
#1Paola Valsasina (UniSR: Vita-Salute San Raffaele University)H-Index: 38
#2Mohammed Aboulwafa (UniSR: Vita-Salute San Raffaele University)H-Index: 1
Last. Maria A. Rocca (UniSR: Vita-Salute San Raffaele University)H-Index: 71
view all 8 authors...
The extent of hypointense lesions of the cervical cord at T1-weighted imaging was greater in the upper than lower cervical level, with a more pronounced involvement of the posterior compared with the anterior cord. These patterns of distribution corresponded to clinical phenotype and disability.
9 CitationsSource
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