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Benjamin Straube
University of Marburg
PsychiatryDevelopmental psychologyPsychologyCognitive psychologyGesture
86Publications
23H-index
1,596Citations
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Publications 110
Newest
#1Anne Suffel (University of Marburg)
#2Arne Nagels (University of Mainz)H-Index: 11
Last. Benjamin Straube (University of Marburg)H-Index: 23
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: The feeling of being addressed is the first step in a complex processing stream enabling successful social communication. Social impairments are a relevant characteristic of patients with major depressive disorder (MDD). Here, we investigated a mechanism which-if impaired-might contribute to withdrawal or isolation in MDD, namely, the neural processing of social cues such as body orientation and gesture. During funtional magnetic resonance imaging (fMRI) data acquisition, 33 patients with MDD ...
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#1Maike Hollandt (University of Greifswald)H-Index: 2
#2Adrian Wroblewski (University of Marburg)H-Index: 1
Last. Jan Richter (University of Greifswald)H-Index: 16
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Extinction learning is suggested to be a central mechanism during exposure-based cognitive behavioral psychotherapy. A positive association between the patients' pretreatment extinction learning performance and treatment outcome would corroborate the hypothesis. Indeed, there is first correlational evidence between reduced extinction learning and therapy efficacy. However, the results of these association studies may be hampered by extinction-training protocols that do not match treatment proced...
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#1Lukas Uhlmann (University of Marburg)H-Index: 1
#2Mareike Pazen (University of Marburg)H-Index: 1
Last. Benjamin Straube (University of Marburg)H-Index: 23
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Forward models can predict sensory consequences of self-action, which is reflected by less neural processing for actively than passively generated sensory inputs (BOLD suppression effect). However, it remains open whether forward models take the identity of a moving body part into account when predicting the sensory consequences of an action. In the current study, fMRI was used to investigate the neural correlates of active and passive hand movements during which participants saw either an on-li...
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#1Mareike Pazen (University of Marburg)H-Index: 1
#2Lukas Uhlmann (University of Marburg)H-Index: 1
Last. Tilo Kircher (University of Marburg)H-Index: 51
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Abstract Tool use is one of the most remarkable skills of the human species, enabling complex interactions with the environment. To establish such interactions, we predict the sensory consequences of our actions based on a copy of the motor command (efference copy), leading to an attenuated perception and neural suppression of the sensory input. Here, we investigated whether and how tools can be incorporated into these predictions. We hypothesized that similar predictive mechanisms are used for ...
1 CitationsSource
#1Adrian Wroblewski (University of Marburg)H-Index: 1
#2Yifei He (University of Marburg)H-Index: 1
Last. Benjamin Straube (University of Marburg)H-Index: 4
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Abstract Integrating visual and auditory information during gesture-speech integration (GSI) is important for successful social communication, which is often impaired in schizophrenia. Several studies suggested the posterior superior temporal sulcus (pSTS) to be a relevant multisensory integration site. However, intact STS activation patterns were often reported in patients. Thus, here we used Dynamic Causal Modelling (DCM) to analyze whether information processing in schizophrenia spectrum diso...
2 CitationsSource
#1Tilo Kircher (University of Marburg)H-Index: 51
#2Johannes T. Krautheim (University of Marburg)H-Index: 1
Last. Benjamin Straube (University of Marburg)H-Index: 23
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#1Isabelle C. Ridderbusch (University of Marburg)
#2Yunbo Yang (University of Marburg)H-Index: 3
Last. U. Lueken (Humboldt University of Berlin)H-Index: 2
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Abstract Neuronal nitric oxide synthase (NOS-I) impacts on fear/anxiety-like behavior in animals. In humans, the short (S) allele of a functional promotor polymorphism of NOS1 (NOS1 ex1f-VNTR) has been shown to be associated with higher anxiety and altered fear conditioning in healthy subjects in the amygdala and hippocampus (AMY/HIPP). Here, we explore the role of NOS1 ex1f-VNTR as a pathophysiological correlate of panic disorder and agoraphobia (PD/AG). In a sub-sample of a multicenter cogniti...
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#1B. Ezgi Arikan (University of Giessen)H-Index: 4
Last. Tilo KircherH-Index: 51
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Sensory consequences of self-generated as opposed to externally generated movements are perceived as less intense and lead to less neural activity in corresponding sensory cortices, presumably due to predictive mechanisms. Self-generated sensory inputs have been mostly studied in a single modality, using abstract feedback, with control conditions not differentiating efferent from reafferent feedback. Here we investigated the neural processing of (a) naturalistic action-feedback associations of (...
3 CitationsSource
#1Isabelle C. Ridderbusch (University of Marburg)
#2Jan Richter (University of Greifswald)H-Index: 16
Last. Benjamin Straube (University of Marburg)H-Index: 23
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Abstract The gene coding for glycine receptor β subunits (GLRB) has been found to be related to panic disorder and agoraphobia (PD/AG) and to be associated with altered insular BOLD activation during fear conditioning, as an intermediate phenotype of defensive system reactivity in healthy subjects. In a multicenter clinical trial on PD/AG patients we investigated in three sub-samples whether GLRB allelic variation (A/G; A-allele identified as «risk») in the single nucleotide polymorphism rs76882...
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#1Milosz Krala (University of Marburg)
#2Bianca M. van Kemenade (University of Marburg)H-Index: 7
Last. Frank Bremmer (University of Marburg)H-Index: 37
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