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Vasileia Balabanidou
Foundation for Research & Technology – Hellas
GeneAnopheles gambiaeGeneticsCuticleBiology
14Publications
4H-index
142Citations
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Publications 15
Newest
#1Kumar Saurabh Singh (University of Exeter)H-Index: 5
#2Bartlomiej J. Troczka (University of Exeter)H-Index: 5
Last. Emma Randall (University of Exeter)H-Index: 5
view all 18 authors...
Host shifts can lead to ecological speciation and the emergence of new pests and pathogens. However, the mutational events that facilitate the exploitation of novel hosts are poorly understood. Here, we characterize an adaptive walk underpinning the host shift of the aphid Myzus persicae to tobacco, including evolution of mechanisms that overcame tobacco chemical defenses. A series of mutational events added as many as 1.5 million nucleotides to the genome of the tobacco-adapted subspecies, M. p...
Source
#1Amy Lynd (LSTM: Liverpool School of Tropical Medicine)H-Index: 11
#2Vasileia Balabanidou (FORTH: Foundation for Research & Technology – Hellas)H-Index: 4
Last. Gareth Lycett (LSTM: Liverpool School of Tropical Medicine)H-Index: 16
view all 7 authors...
Oenocytes are an insect cell type having diverse physiological functions ranging from cuticular hydrocarbon (CHC) production to insecticide detoxification that may impact their capacity to transmit pathogens. To develop functional genetic tools to study Anopheles gambiae oenocytes, we have trapped an oenocyte enhancer to create a transgenic mosquito Gal4 driver line that mediates tissue-specific expression. After crossing with UAS-reporter lines, An. gambiae oenocytes are fluorescently tagged th...
3 CitationsSource
#1Vasileia Balabanidou (FORTH: Foundation for Research & Technology – Hellas)H-Index: 4
#2Mary Kefi (FORTH: Foundation for Research & Technology – Hellas)H-Index: 2
Last. John Vontas (FORTH: Foundation for Research & Technology – Hellas)H-Index: 42
view all 13 authors...
Malaria incidence has halved since the year 2000, with 80% of the reduction attributable to the use of insecticides. However, insecticide resistance is now widespread, is rapidly increasing in spec...
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#2Mary KefiH-Index: 2
Last. John VontasH-Index: 42
view all 13 authors...
Source
#1Mary Kefi (FORTH: Foundation for Research & Technology – Hellas)H-Index: 2
#2Vasileia Balabanidou (FORTH: Foundation for Research & Technology – Hellas)H-Index: 4
Last. John Vontas (FORTH: Foundation for Research & Technology – Hellas)H-Index: 42
view all 6 authors...
Abstract Cuticular hydrocarbon (CHC) biosynthesis is a major pathway of insect physiology. In Drosophila melanogaster the cytochrome P450 CYP4G1 catalyses the insect-specific oxidative decarbonylation step, while in the malaria vector Anopheles gambiae, two CYP4G paralogues, CYP4G16 and CYP4G17 are present. Analysis of the subcellular localization of CYP4G17 and CYP4G16 in larval and pupal stages revealed that CYP4G16 preserves its PM localization across developmental stages analyzed; however CY...
3 CitationsSource
#1Eba Alemayehu Simma (UPR-RP: UPRRP College of Natural Sciences)H-Index: 1
#2Wannes Dermauw (UGent: Ghent University)H-Index: 25
Last. Thomas Van Leeuwen (UGent: Ghent University)H-Index: 37
view all 10 authors...
3 CitationsSource
#1Eba Alemayehu Simma (UPR-RP: UPRRP College of Natural Sciences)H-Index: 1
#2Wannes Dermauw (UGent: Ghent University)H-Index: 25
Last. Thomas Van Leeuwen (UGent: Ghent University)H-Index: 37
view all 10 authors...
BACKGROUND: Vector control is the main intervention in malaria control and elimination strategies. However, the development of insecticide resistance is one of the major challenges for controlling malaria vectors. Anopheles arabiensis populations in Ethiopia showed resistance against both DDT and the pyrethroid deltamethrin. Although a L1014F target-site resistance mutation was present in the voltage gated sodium channel of investigated populations, the levels of resistance and biochemical studi...
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#1Vasileia Balabanidou (FORTH: Foundation for Research & Technology – Hellas)H-Index: 4
#2Linda Grigoraki (UoC: University of Crete)H-Index: 8
Last. John Vontas (FORTH: Foundation for Research & Technology – Hellas)H-Index: 42
view all 3 authors...
Intense use of insecticides has resulted in the selection of extreme levels of resistance in insect populations. Therefore understanding the molecular basis of insecticide resistance mechanisms becomes critical. Penetration resistance refers to modifications in the cuticle that will eventually slow down the penetration of insecticide molecules within insects' body. So far, two mechanisms of penetration resistance have been described, the cuticle thickening and the altering of cuticle composition...
22 CitationsSource
#1Gildas A. Yahouédo (IRD: Institut de recherche pour le développement)H-Index: 3
#2Fabrice Chandre (IRD: Institut de recherche pour le développement)H-Index: 46
Last. Sylvie Cornelie (IRD: Institut de recherche pour le développement)H-Index: 18
view all 9 authors...
2 CitationsSource
#1Patricia PignatelliH-Index: 12
#2Victoria InghamH-Index: 4
Last. Hilary RansonH-Index: 68
view all 6 authors...
The role of ABC transporters in conferring insecticide resistance has received much attention recently. Here we identify ABC transporters differentially expressed in insecticide resistant populations of the malaria vector, Anopheles gambiae. Although we found little evidence that the orthologs of the multidrug resistance proteins described in other species are associated with resistance in An. gambiae we did identify a subset of ABC proteins consistently differentially expressed in pyrethroid re...
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