Koichi Kato
Nagoya City University
Publications 535
Published on Apr 1, 2019in Biochimica et Biophysica Acta 3.44
Yoichiro Harada1
Estimated H-index: 1
(Kagoshima University),
Takehiro Suzuki30
Estimated H-index: 30
+ 10 AuthorsNaoyuki Taniguchi86
Estimated H-index: 86
Abstract Background Cells secrete heterogeneous populations of extracellular vesicles (EVs) via unknown mechanisms. EV biogenesis has been postulated to involve lipid-protein clusters, also known as membrane microdomains. Methods Membrane properties and heterogeneity of melanoma-derived EVs were analyzed by a detergent solubilization assay, sucrose density gradient ultracentrifugation and immunoprecipitation. EV secretion was modulated by RNA interference and pharmacological treatments. Results ...
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Published on Mar 13, 2019in Scientific Reports 4.12
Estimated H-index: 2
(Nagoya University),
Yoshiko Takeda-Uchimura7
Estimated H-index: 7
(Nagoya University)
+ 7 AuthorsKenji Uchimura17
Estimated H-index: 17
(Lille University of Science and Technology)
Keratan sulfate (KS) is a carbohydrate side chain covalently attached to extracellular proteoglycans. KS is composed of disaccharide units of 6-sulfated N-acetylglucosamine (GlcNAc) and galactose. We have previously shown that GlcNAc-6-O-sulfotransferase (GlcNAc6ST) 1 encoded by Chst2 is an enzyme necessary for the synthesis of GlcNAc-6-sulfated KS chains that are required for neuronal plasticity in the visual cortex of the mouse brain during the critical period, but not in adulthood. Here, we s...
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Published on Jan 2, 2019in mAbs 5.17
Robert G. Brinson8
Estimated H-index: 8
(National Institute of Standards and Technology),
John P. Marino23
Estimated H-index: 23
(National Institute of Standards and Technology)
+ 46 AuthorsGregory K. Pierens14
Estimated H-index: 14
(University of Queensland)
The increased interest in using monoclonal antibodies (mAbs) as a platform for biopharmaceuticals has led to the need for new analytical techniques that can precisely assess physicochemical properties of these large and very complex drugs for the purpose of correctly identifying quality attributes (QA). One QA, higher order structure (HOS), is unique to biopharmaceuticals and essential for establishing consistency in biopharmaceutical manufacturing, detecting process-related variations from manu...
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Published on Jan 10, 2019in Journal of Physical Chemistry B 3.15
Satoru G. Itoh14
Estimated H-index: 14
(Graduate University for Advanced Studies),
Maho Yagi-Utsumi6
Estimated H-index: 6
+ 1 AuthorsHisashi Okumura18
Estimated H-index: 18
(Graduate University for Advanced Studies)
Oligomer formation of amyloid-β peptides (Aβ) is accelerated at a hydrophilic/hydrophobic interface. However, details of the acceleration mechanism have not been elucidated. To understand the effects of the interface on oligomerization at the atomic level, we performed molecular dynamics simulations for an Aβ40 monomer in the presence and absence of the hydrophilic/hydrophobic interface. Nuclear magnetic resonance experiments of Aβ40 peptides with gangliosidic micelles were also carried out. In ...
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Published on Mar 27, 2019in Journal of Physical Chemistry B 3.15
Tomoki Nakayoshi2
Estimated H-index: 2
Koichi Kato52
Estimated H-index: 52
+ 1 AuthorsAkifumi Oda12
Estimated H-index: 12
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Published on Oct 1, 2018in Applied Physics Express 2.56
T. Kaneko15
Estimated H-index: 15
Nobuo Tajima22
Estimated H-index: 22
+ 4 AuthorsTakahisa Ohno25
Estimated H-index: 25
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Published on Apr 1, 2018in Biomolecular Nmr Assignments 0.59
Rina Yogo3
Estimated H-index: 3
(Nagoya City University),
Saeko Yanaka4
Estimated H-index: 4
(Nagoya City University),
Koichi Kato52
Estimated H-index: 52
(Nagoya City University)
Fcγ receptor (FcγR) promotes various immune responses through interactions with the Fc portion of immunoglobulin G (IgG). FcγRIIIb is a glycosylphosphatidylinositol-linked protein expressed on neutrophils and triggers degranulation and opsonic phagocytosis. The extracellular region of FcγR is composed of two Ig-fold domains and can be cleaved as a soluble form (sFcγRIIIb), which is also reactive with complement receptor type 3. Although structure and Fc interaction of sFcγRIIIb have been charact...
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Published on May 1, 2018in Chirality 1.83
Tomoki Nakayoshi2
Estimated H-index: 2
(Kanazawa University),
Koichi Kato52
Estimated H-index: 52
(Meijo University)
+ 3 AuthorsAkifumi Oda12
Estimated H-index: 12
(Kanazawa University)
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Published on May 1, 2018in FEBS Journal 4.53
Nongluk Sriwilaijaroen12
Estimated H-index: 12
(Thammasat University),
Shin-ichi Nakakita13
Estimated H-index: 13
(Kagawa University)
+ 11 AuthorsYasushi Kanai5
Estimated H-index: 5
(Osaka University)
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