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Hiroko Tsukamura
Nagoya University
EndocrinologyKisspeptinLuteinizing hormoneOvariectomized ratBiology
206Publications
41H-index
6,056Citations
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Publications 210
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#1Yasuhiro Morita (Nagoya University)H-Index: 14
#2Riho Ozaki (Nagoya University)
Last. Hiroko Tsukamura (Nagoya University)H-Index: 41
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#1Kei Horihata (Nagoya University)
#2Naoko Inoue (Nagoya University)H-Index: 22
Last. Hiroko Tsukamura (Nagoya University)H-Index: 41
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#1Nahoko Ieda (Nagoya University)H-Index: 7
#2Assadullah (Nagoya University)H-Index: 1
Last. Hiroko Tsukamura (Nagoya University)H-Index: 41
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#1Fuko Matsuda (UTokyo: University of Tokyo)H-Index: 11
#2Satoshi Ohkura (Nagoya University)H-Index: 22
Last. Hiroko Tsukamura (Nagoya University)H-Index: 41
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#1Nahoko Ieda (Nagoya University)H-Index: 7
#2Ahmed Sa Hassaneen (SVU: South Valley University)
Last. Hiroko Tsukamura (Nagoya University)H-Index: 41
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The discovery of the role of kisspeptin neurons in the regulation of mammalian reproduction in 2003 was one of the biggest breakthroughs in reproductive endocrinology within the last few decades. Research during the past two decades since the discovery of kisspeptin has been unveiling the mechanism of how the hypothalamic kisspeptin neurons control reproductive functions through regulation of gonadotropin-releasing hormone (GnRH) secretion. This article aims to overview kisspeptin research, incl...
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#1T. Sasaki (Nagoya University)
#2D. Ito (Nagoya University)H-Index: 1
Last. Satoshi Ohkura (Nagoya University)H-Index: 22
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Abstract Pulsatile gonadotropin-releasing hormone (GnRH) secretion is indispensable for reproduction in mammals. Kisspeptin neurons in the hypothalamic arcuate nucleus (ARC), referred to as KNDy neurons because of the coexpression of neurokinin B and dynorphin A, are considered as components of the GnRH pulse generator that produces rhythmic GnRH secretion. The present study aimed to investigate if peripheral administration of PF-4455242, a κ-opioid receptor (KOR, a dynorphin A receptor) antagon...
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#1Yoshihisa Uenoyama (Nagoya University)H-Index: 25
#2Naoko Inoue (Nagoya University)H-Index: 22
Last. Hiroko Tsukamura (Nagoya University)H-Index: 41
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Pubertal onset is thought to be timed by an increase in pulsatile gonadotropin-releasing hormone (GnRH)/gonadotropin secretion in mammals. The underlying mechanism of pubertal onset in mammals is still an open question. Evidence accumulated in the last 15 years suggests that kisspeptin/neurokinin B/dynorphin A (KNDy) neurons in the hypothalamic arcuate nucleus play a key role in pubertal onset by triggering pulsatile GnRH/gonadotropin secretin in mammals. Specifically, KNDy neurons are now consi...
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#1Shiori Minabe (UTokyo: University of Tokyo)H-Index: 1
#2Marimo Sato (UTokyo: University of Tokyo)H-Index: 1
Last. Hiroko Tsukamura (Nagoya University)H-Index: 41
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1 CitationsSource
#1Shiori Minabe (UTokyo: University of Tokyo)H-Index: 1
#2Sho Nakamura (UTokyo: University of Tokyo)H-Index: 8
Last. Fuko Matsuda (UTokyo: University of Tokyo)H-Index: 11
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#1Jing Chen (UTokyo: University of Tokyo)
#2Shiori Minabe (UTokyo: University of Tokyo)H-Index: 1
Last. Fuko Matsuda (UTokyo: University of Tokyo)H-Index: 11
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