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Paul Muhle
University of Münster
SwallowingPhysical therapyDysphagiaStrokeMedicine
28Publications
7H-index
126Citations
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Publications 30
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#1Bendix Labeit (WWU: University of Münster)H-Index: 1
#2Inga ClausH-Index: 3
Last. Tobias WarneckeH-Index: 24
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Abstract Introduction The pathophysiology of dysphagia in Parkinson's disease (PD) is heterogeneous and poorly understood at present. This study investigated the phenotypes, prevalence and pathophysiology of oropharyngeal freezing (OPF) in PD and its relation to dysphagia. Methods In a prospective study, 50 PD patients were systematically screened for OPF using flexible endoscopic evaluation of swallowing (FEES). In addition, FEES-videos of 50 patients with post-stroke dysphagia and 50 healthy s...
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#1Bendix Labeit (WWU: University of Münster)H-Index: 1
#2Inga ClausH-Index: 3
Last. Tobias WarneckeH-Index: 24
view all 6 authors...
Background. Pharyngeal dysphagia is a common symptom of Parkinson’s disease (PD) leading to severe complications. PD-related pharyngeal dysphagia (PDrPD) may significantly improve in up to half of patients following acute oral levodopa challenge. Objective. The aim of this study was to investigate the effects of levodopa-carbidopa intestinal gel (LCIG) on PDrPD. Methods. Forty-five PD patients under LCIG treatment were available for retrospective analysis. In all patients with PDrPD who underwen...
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#1Bendix LabeitH-Index: 1
#2Paul MuhleH-Index: 7
Last. Rainer DziewasH-Index: 34
view all 9 authors...
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#2Sarah SchmidtH-Index: 1
Last. Rainer DziewasH-Index: 34
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Background and Purpose— Predicting safe extubation represents a clinical challenge in acute stroke patients. Classical respiratory weaning criteria have not proven reliable. Concerning the paramoun...
2 CitationsSource
#1Bendix LabeitH-Index: 1
#2Paul MuhleH-Index: 7
Last. Tobias WarneckeH-Index: 24
view all 7 authors...
Dysphagia can be predominant or sole symptom of myositis. However, diagnostic evaluation is difficult in such cases. Here, we present evidence for dysphagia as sole manifestation of Jo-1 associated myositis. A 77-year-old patient suffering from isolated dysphagia was assessed by flexible endoscopic evaluation of swallowing, videofluoroscopy, high resolution oesophageal manometry, whole body muscle MRI, electroneurographic and electromyographic examination, cerebrospinal fluid analysis, screening...
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1 CitationsSource
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#2Thomas MarianH-Index: 4
Last. Tobias WarneckeH-Index: 24
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Introduction: Although patients with Parkinson's disease (PD) often suffer from oropharyngeal dysphagia, knowledge about the underlying pathophysiological mechanisms is limited. Substance P (SP) is a localization-independent neurotransmitter of the entire nervous system. Reduced levels of SP were found in saliva of patients with impaired cough reflex and in advanced stages of PD. The aim of the study was to investigate SP in PD patients in order to gain further insights into the underlying patho...
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#1Bendix Labeit (MIT: Massachusetts Institute of Technology)
#2Paul MuhleH-Index: 7
Last. Rainer Dziewas (MIT: Massachusetts Institute of Technology)H-Index: 1
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#2Thomas MarianH-Index: 4
Last. Rainer DziewasH-Index: 34
view all 11 authors...
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