Manisha Madhoo
Shire plc
Publications 16
#1Manjiri Pawaskar (Shire plc)H-Index: 7
#2Moshe FridmanH-Index: 17
Last.Manisha Madhoo (Shire plc)H-Index: 6
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Objective: Investigate the association between diagnosis and outcomes in adults with symptoms of ADHD. Method: The Validate Attitudes and Lifestyle Issues in Depression, ADHD and Troubles with Eati...
1 CitationsSource
#1Timothy WigalH-Index: 46
#2Matthew Brams (BCM: Baylor College of Medicine)H-Index: 15
Last.Manisha Madhoo (Shire plc)H-Index: 6
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AbstractObjectives: Evaluate the efficacy, duration of effect, and tolerability of SHP465 mixed amphetamine salts (MAS) extended-release versus placebo and immediate-release MAS (MAS IR) in adults with attention-deficit/hyperactivity disorder (ADHD).Methods: Adults with ADHD Rating Scale, Version IV (ADHD-RS-IV) scores ≥24 were randomized to SHP465 MAS (50 or 75 mg), placebo, or 25 mg MAS IR in a double-blind, 3-period, crossover study using a simulated adult workplace environment. On the final ...
2 CitationsSource
#1Hunna J. Watson (UNC: University of North Carolina at Chapel Hill)H-Index: 18
#2Andreas Jangmo (KI: Karolinska Institutet)H-Index: 6
Last.Cynthia M. Bulik (KI: Karolinska Institutet)H-Index: 88
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Abstract Objective Capturing trends in healthcare utilization may help to improve efficiencies in the detection and diagnosis of illness, to plan service delivery, and to forecast future health expenditures. For binge-eating disorder (BED), issues include lengthy delays in detection and diagnosis, missed opportunities for recognition and treatment, and morbidity. The study objective was to compare healthcare utilization and expenditure in people with and without BED. Methods A case-control desig...
2 CitationsSource
#1Timothy WigalH-Index: 46
#2Ann C. ChildressH-Index: 19
Last.Manisha Madhoo (Shire plc)H-Index: 6
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ABSTRACTObjectives: Evaluate the efficacy, duration of effect, and safety of 25 mg SHP465 mixed amphetamine salts (MAS) extended-release versus placebo in adults with attention-deficit/hyperactivity disorder (ADHD).Methods: Adults (18–55 years) with ADHD and with ADHD Rating Scale-IV (ADHD-RS-IV) scores ≥24 were randomized to treatment in a double-blind, 2-period, 2-treatment crossover study utilizing the Adult Workplace Environment (AWE), as described by Wigal and Wigal (J Atten Disord 2006;10:...
3 CitationsSource
#1Cynthia Richards (Shire plc)H-Index: 6
#2Roger S. McIntyre (U of T: University of Toronto)H-Index: 61
Last.Manisha Madhoo (Shire plc)H-Index: 6
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Abstract Background The efficacy, safety, and tolerability of lisdexamfetamine dimesylate (LDX) augmentation of antidepressant monotherapy in adults with major depressive disorder (MDD) from two phase 3 studies are reported. Methods Across study 1 (placebo, n=201; LDX, n=201) and study 2 (placebo, n=213; LDX, n=211), most participants (placebo and LDX) in the safety analysis set were female (study 1: 66.2% and 64.2%; study 2: 67.1% and 66.8%); mean±SD ages were 41.8±12.04 with placebo and 42.2±1...
6 CitationsSource
#1Asha HareendranH-Index: 8
#2J. Setyawan (Shire plc)H-Index: 11
Last.M. Haim Erder (Shire plc)H-Index: 20
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Background Engaging adolescents in decisions about their health may enhance their compliance with treatment and result in better health outcomes. Treatment outcomes in attention-deficit/hyperactivity disorder (ADHD) are rarely evaluated from the adolescents’ point of view. There is also concern that adolescents with ADHD may not have insight about the impacts of their disease. This article describes research conducted to understand the experiences of adolescents with ADHD and how the research wa...
2 CitationsSource
#1Mark Thomas (UA: University of Alabama)H-Index: 2
#2Anthony L. Rostain (UPenn: University of Pennsylvania)H-Index: 16
Last.Manisha Madhoo (Shire plc)H-Index: 6
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Objective: To assess perceptions concerning ADHD among U.S. college healthcare providers. Method: A 37-question survey was conducted from October 4 to December 2, 2010. Participants were contacted via mail or telephone and compensated for participation. Results: Thirty-eight percent of the respondents (physicians, n = 59; nurses, n = 138; directors, n = 101) viewed ADHD as a “problem”/“very much a problem” at their institution. Referrals for evaluation came from students (84%), psychologists/cou...
7 CitationsSource
#1L. Eugene Arnold (OSU: Ohio State University)H-Index: 70
#2P Hodgkins (Vertex Pharmaceuticals)H-Index: 8
Last.Geoff KewleyH-Index: 1
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Objective: The aim of this study was to synthesize published data regarding long-term effects of ADHD on information learned (measured via achievement tests) and success within the school environment (academic performance). Method: A systematic search identified 176 studies (1980-2012) of long-term (≥2 years) academic outcomes with ADHD. Results: Achievement test outcomes (79%) and academic performance outcomes (75%) were worse in individuals with untreated ADHD compared with non-ADHD controls, ...
39 CitationsSource