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Markus Fischer
University of Hamburg
496Publications
65H-index
17.4kCitations
Publications 497
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#1Kristina KappelH-Index: 6
Last.Jan FritscheH-Index: 23
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Abstract Seafood is particularly susceptible to the substitution of species. In order to guarantee authentic seafood products, seafood processors and traders must perform self-checks on the authenticity of imported and purchased goods. However, the conventional Sanger sequencing of PCR products for the authentication of seafood species is time-consuming and requires advanced infrastructure. DNA microarrays (DNA chips) with species-specific oligonucleotide probes represent a rapid alternative to ...
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#1Rafael Molina-Venegas (University of Bern)H-Index: 2
#2Markus Fischer (University of Bern)H-Index: 65
Last.Andreas Hemp (University of Bayreuth)H-Index: 29
view all 3 authors...
Accumulating evidence suggests that species sensitivity to climatic change is strongly related to their ecological niches, which are somewhat evolutionary conserved. Insofar as this is true, climate change-driven extinctions may be non-random with respect to phylogeny, and entire branches of the tree of life might be lost. In mountainous regions, where macroecological conditions change abruptly with elevation, evolutionarily lineages may show deep phylogenetic turnover along elevational belts, a...
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Head and neck squamous cell carcinoma (HNSCC) is known to overexpress a variety of receptor tyrosine kinases, such as the HGF receptor Met. Like other malignancies, HNSCC involves a mutual interaction between the tumor cells and surrounding tissues and cells. We hypothesized that activation of HGF/Met signaling in HNSCC influences glucose metabolism and therefore substantially changes the tumor microenvironment. To determine the effect of HGF, we submitted three established HNSCC cell lines to m...
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#1Yanhao Feng (Lanzhou University)H-Index: 5
#2Santiago Soliveres (University of Bern)H-Index: 29
Last.Markus Fischer (University of Bern)H-Index: 65
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The inference of pairwise competitive outcomes (PCO) and multispecies competitive ranks and intransitivity from empirical data is essential to evaluate how competition shapes plant communities. Three categories of methods, differing in theoretical background and data requirements, have been used: (a) theoretically sound coexistence theory‐based methods, (b) index‐based methods, and (c) ‘process‐from‐pattern’ methods. However, how they are related is largely unknown. In this study, we explored th...
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#1Christine Felbinger (UHH: University of Hamburg)H-Index: 2
#2Florian Kutzsche (UHH: University of Hamburg)
Last.Markus Fischer (UHH: University of Hamburg)H-Index: 65
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Abstract The present work demonstrates a fast and cost efficient method to verify the authenticity of hazelnut cultivars. RAPD-PCR analysis was used to experimentally check 13 different hazelnut cultivars by using 16 RAPD-primers. It was possible to distinguish between all hazelnut cultivars by agarose gel electrophoresis band pattern. For an easier evaluation, which primer should be used to confirm one of the cultivars, the band pattern was transferred into bar diagrams. Furthermore, a cultivar...
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#1Sabine Richert (University of Freiburg)H-Index: 2
#2Jing Chen (University of Freiburg)
Last.S. Weber (University of Freiburg)H-Index: 39
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Due to their biological importance, the photochemistry of blue-light photoreceptor proteins has been studied extensively over the last few decades. Most blue-light photoreceptors, such as cryptochromes and phototropins, utilize flavin chromophores as their cofactors. After irradiation with light, the chromophore undergoes electron transfer with nearby redox-active amino-acid residues within the protein, whereby this first step of signal transduction may be initiated either from the flavin’s exci...
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#1Nils Pompe (University of Freiburg)H-Index: 3
#2Jing Chen (University of Freiburg)
Last.S. Weber (University of Freiburg)H-Index: 39
view all 7 authors...
In this contribution, the relative hyperfine couplings are determined for the 1H nuclei of the flavin mononucleotide (FMN) radical in an aqueous environment. In addition, three structural analogs with different methylation patterns are characterized and the influence of the substituents at the isoalloxazine moiety on the electronic structure of the radicals is explored. By exploiting nuclear hyperpolarization generated via the photo-CIDNP (chemically induced dynamic nuclear polarization) effect,...
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#1Soyeon Bae (University of Würzburg)H-Index: 1
#2Shaun R. Levick (CDU: Charles Darwin University)H-Index: 24
Last.Jörg Müller (University of Würzburg)H-Index: 51
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Recent progress in remote sensing provides much-needed, large-scale spatio-temporal information on habitat structures important for biodiversity conservation. Here we examine the potential of a newly launched satellite-borne radar system (Sentinel-1) to map the biodiversity of twelve taxa across five temperate forest regions in central Europe. We show that the sensitivity of radar to habitat structure is similar to that of airborne laser scanning (ALS), the current gold standard in the measureme...
1 CitationsSource
#1Rafael Molina-Venegas (University of Bern)H-Index: 2
#2Markus Fischer (University of Bern)H-Index: 65
Last.Andreas Hemp (University of Bayreuth)H-Index: 29
view all 3 authors...
Aim: Previous studies have shown that phylogenetic divergence (i.e. the average phylogenetic displacement between species in a community) is highly sensitive to the underlying branching patterns of phylogenies, suggesting that there is a need to integrate both facets of phylogenic information to obtain a better understanding of assemblage structure. Here, we formally conceptualize the three fundamental branching patterns that can drive phylogenetic divergence, and propose a method to identify th...
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#1Malte Holzapfel (UHH: University of Hamburg)H-Index: 2
Last.Wolfgang Maison (UHH: University of Hamburg)H-Index: 18
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The development of novel prostate-specific membrane antigen (PSMA)-targeted radioactive theranostic agents is currently limited to facilities capable of working with high-energy radioisotopes. Even preselection of lead structures in vitro relies mostly on radioactive assays with PSMA(+) LNCaP and PSMA(−) PC-3 cells. Assays utilizing radioisotopes are time consuming, costly, and limit discovery to a small group of scientists with special facilities. Nonradioactive alternatives are therefore neede...
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