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Rozanna Meijboom
Erasmus University Rotterdam
9Publications
5H-index
212Citations
Publications 9
Newest
#1Rozanna Meijboom (EUR: Erasmus University Rotterdam)H-Index: 5
#2Rebecca M. E. Steketee (EUR: Erasmus University Rotterdam)H-Index: 6
Last.Marion Smits (EUR: Erasmus University Rotterdam)H-Index: 25
view all 9 authors...
Objectives This study explored group-wise quantitative measures of tract-specific white matter (WM) microstructure and functional default mode network (DMN) connectivity to establish an initial indication of their clinical applicability for early-stage and follow-up differential diagnosis of Alzheimer’s disease (AD) and behavioural variant frontotemporal dementia (bvFTD).
#1Esther E. Bron (EUR: Erasmus University Rotterdam)H-Index: 12
#2Marion Smits (EUR: Erasmus University Rotterdam)H-Index: 25
Last.Stefan Klein (EUR: Erasmus University Rotterdam)H-Index: 25
view all 9 authors...
Objectives To investigate the added diagnostic value of arterial spin labelling (ASL) and diffusion tensor imaging (DTI) to structural MRI for computer-aided classification of Alzheimer's disease (AD), frontotemporal dementia (FTD), and controls.
#1Rozanna Meijboom (EUR: Erasmus University Rotterdam)H-Index: 5
#2Rebecca M. E. Steketee (EUR: Erasmus University Rotterdam)H-Index: 6
Last.Marion Smits (EUR: Erasmus University Rotterdam)H-Index: 25
view all 9 authors...
Objectives Phenocopy frontotemporal dementia (phFTD) is a rare and poorly understood clinical syndrome. PhFTD shows core behavioural variant FTD (bvFTD) symptoms without associated cognitive deficits and brain abnormalities on conventional MRI and without progression. In contrast to phFTD, functional connectivity and white matter (WM) microstructural abnormalities have been observed in bvFTD. We hypothesise that phFTD belongs to the same disease spectrum as bvFTD and investigated whether functio...
#1Rozanna Meijboom (EUR: Erasmus University Rotterdam)H-Index: 5
#2Rebecca M. E. Steketee (EUR: Erasmus University Rotterdam)H-Index: 6
Last.Marion Smits (EUR: Erasmus University Rotterdam)H-Index: 25
view all 6 authors...
Semantic dementia (SD) and behavioral variant frontotemporal dementia (bvFTD), subtypes of frontotemporal dementia, are characterized by distinct clinical symptoms and neuroimaging features, with predominant left temporal grey matter (GM) atrophy in SD and bilateral or right frontal GM atrophy in bvFTD. Such differential hemispheric predilection may also be reflected by other neuroimaging features, such as brain connectivity. This study investigated white matter (WM) microstructure and functiona...
#1Rinske A. Gotink (EUR: Erasmus University Rotterdam)H-Index: 7
#2Rozanna Meijboom (EUR: Erasmus University Rotterdam)H-Index: 5
Last.M. G. Myriam Hunink (Harvard University)H-Index: 69
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Abstract The objective of the current study was to systematically review the evidence of the effect of secular mindfulness techniques on function and structure of the brain. Based on areas known from traditional meditation neuroimaging results, we aimed to explore a neuronal explanation of the stress-reducing effects of the 8-week Mindfulness Based Stress Reduction (MBSR) and Mindfulness Based Cognitive Therapy (MBCT) program. Methods We assessed the effect of MBSR and MBCT (N = 11, all MBSR), c...
#1Rebecca M. E. Steketee (EUR: Erasmus University Rotterdam)H-Index: 6
#2Rozanna Meijboom (EUR: Erasmus University Rotterdam)H-Index: 5
Last.Marion Smits (EUR: Erasmus University Rotterdam)H-Index: 25
view all 8 authors...
This study investigates regional coherence between white matter (WM) microstructure and gray matter (GM) volume and perfusion measures in Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD) using a correlational approach. WM-GM coherence, compared with controls, was stronger between cingulum WM and frontotemporal GM in AD, and temporoparietal GM in bvFTD. In addition, in AD compared with controls, coherence was stronger between inferior fronto-occipital fasciculus WM ...
#1Rebecca M. E. Steketee (EUR: Erasmus University Rotterdam)H-Index: 6
#2Rozanna Meijboom (EUR: Erasmus University Rotterdam)H-Index: 5
Last.John VanSwieten (EUR: Erasmus University Rotterdam)H-Index: 68
view all 10 authors...
Purpose ‘Phenocopy’ frontotemporal dementia (phFTD) patients may clinically mimic the behavioral variant of FTD (bvFTD), but do not show functional decline or abnormalities upon visual inspection of routine neuroimaging. We aimed to identify abnormalities in gray matter (GM) volume and perfusion in phFTD and to assess whether phFTD belongs to the FTD spectrum. We compared phFTD patients with both healthy controls and bvFTD patients.
#1Rebecca M. E. Steketee (EUR: Erasmus University Rotterdam)H-Index: 6
#2Esther E. Bron (EUR: Erasmus University Rotterdam)H-Index: 12
Last.A. van der Lugt (EUR: Erasmus University Rotterdam)H-Index: 65
view all 10 authors...
Objective To investigate arterial spin labeling (ASL)-MRI for the early diagnosis of and differentiation between the two most common types of presenile dementia: Alzheimer’s disease (AD) and frontotemporal dementia (FTD), and for distinguishing age-related from pathological perfusion changes.
#1Esther E. Bron (EUR: Erasmus University Rotterdam)H-Index: 12
#2Marion Smits (EUR: Erasmus University Rotterdam)H-Index: 25
Last.Rozanna Meijboom (EUR: Erasmus University Rotterdam)H-Index: 5
view all 10 authors...
Algorithms for computer-aided diagnosis of dementia based on structural MRI have demonstrated high performance in the literature, but are difficult to compare as different data sets and methodology were used for evaluation. In addition, it is unclear how the algorithms would perform on previously unseen data, and thus, how they would perform in clinical practice when there is no real opportunity to adapt the algorithm to the data at hand. To address these comparability, generalizability and clin...
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