Rick A. Nishimura Mdfacc
Mayo Clinic
Publications 625
#1Erin A. Fender (Mayo Clinic)H-Index: 8
#2Ioana Petrescu (Mayo Clinic)H-Index: 1
Last.Rick A. Nishimura Mdfacc (Mayo Clinic)H-Index: 112
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Abstract Objective To define mortality associated with isolated tricuspid regurgitation (TR) and identify risk factors associated with decreased survival. Patients and Methods We conducted a retrospective cohort study of residents of southeastern Minnesota with moderate-severe or more severe isolated TR diagnosed between January 1, 2005, and April 15, 2015. Isolated TR was defined as TR in the absence of left-sided heart disease or pulmonary hypertension. Patients with an ejection fraction of le...
2 CitationsSource
#1Wei Zhou (Mayo Clinic)H-Index: 2
#2J. Martijn Bos (Mayo Clinic)H-Index: 28
Last.Michael John Ackerman (Mayo Clinic)H-Index: 102
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Hypertrophic cardiomyopathy (HCM), characterized by unexplained left ventricular hypertrophy, is one of the most common heritable cardiovascular diseases. The myosin regulatory light chain (MYL2) mutation R58Q has been associated with severe cardiac hypertrophy and sudden cardiac death (SCD). Herein, we provide the first patient-specific, induced pluripotent stem cell–derived cardiomyocyte (iPSC-CM) model of MYL2-R58Q. The MYL2-R58Q iPSC-CMs were nearly 30% larger than control iPSC-CMs at day 60...
2 CitationsSource
#1Anita Nguyen (Mayo Clinic)H-Index: 4
#2Hartzell V. Schaff (Mayo Clinic)H-Index: 108
Last.Steve R. Ommen (Mayo Clinic)H-Index: 60
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Background Survival of patients with obstructive hypertrophic cardiomyopathy who undergo septal myectomy appears to be excellent and, in some series, is similar to that of matched populations. In this study, we investigated causes of late death in a large cohort of surgical patients. Methods Between January 1961 and October 2017, 2,956 patients underwent surgery for hypertrophic cardiomyopathy. We reviewed medical records of these patients. Vital status and causes of mortality were verified usin...
#1Brenden S Ingraham (Mayo Clinic)H-Index: 1
#2Sorin V. Pislaru (Mayo Clinic)H-Index: 23
Last.Mackram F. Eleid (Mayo Clinic)H-Index: 23
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Objective This study aimed to identify characteristics, spectrum of tricuspid regurgitation (TR) severity and treatment patterns in patients considered for intervention of severe TR at a tertiary centre. The population being considered for TR intervention is currently not well defined and the role of transcatheter interventions is unclear. Methods The study involved 87 patients with severe TR considered for intervention from 1 March 2016 to 12 November 2018 at Mayo Clinic. Patients receiving med...
4 CitationsSource
#1Sungrim Moon (Mayo Clinic)H-Index: 7
#2Sijia Liu (Mayo Clinic)H-Index: 8
Last.Adelaide M. Arruda-Olson (Mayo Clinic)H-Index: 12
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Abstract Background: The management of hypertrophic cardiomyopathy (HCM) patients requires the knowledge of risk factors associated with sudden cardiac death (SCD). SCD risk factors such as syncope and family history of SCD (FH-SCD) as well as family history of HCM (FH-HCM) are documented in electronic health records (EHRs) as clinical narratives. Automated extraction of risk factors from clinical narratives by natural language processing (NLP) may expedite management workflow of HCM patients. T...
1 CitationsSource
#1Jeong Hoon YangH-Index: 1
#2William R. Miranda (Mayo Clinic)H-Index: 9
Last.Jae Kuen OhH-Index: 96
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Abstract Background Cardiac filling pressures may be elevated due to abnormalities in the myocardium, heightened pericardial restraint, or both. The authors hypothesized that the relative contributions due to myocardium and pericardium could be estimated by the ratio between right atrial pressure and pulmonary arterial wedge pressure (RAP/PAWP), which would enable better discrimination of the extent of myocardial disease in patients with constrictive pericarditis (CP). Objectives This study inve...
1 CitationsSource
#1Rick A. Nishimura Mdfacc (Mayo Clinic)H-Index: 112
#2Barry A. Borlaug (Mayo Clinic)H-Index: 56
Abstract Diastolic filling of the heart is a complex sequence of multiple inter-related events consisting of processes such as ventricular relaxation, erectile coronary effect, visco-elastic forces of the myocardium, ventricular interaction, myocardial stress strain relationships, pericardial restraint, passive filling, and atrial contraction. However, in order to understand diastolic filling from a clinical aspect, a simplified foundation can be used which divides the cardiac cycle into contrac...
1 CitationsSource
#1Mackram F. Eleid (Mayo Clinic)H-Index: 23
#2Rick A. Nishimura Mdfacc (Mayo Clinic)H-Index: 112
#1Yogesh N.V. Reddy (Mayo Clinic)H-Index: 19
#2Rick A. Nishimura Mdfacc (Mayo Clinic)H-Index: 112
1 CitationsSource