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Vladimír Hampl
Charles University in Prague
56Publications
21H-index
2,697Citations
Publications 56
Newest
Published on Mar 11, 2019in bioRxiv
A. M. Novak Vanclova , Martin Zoltner8
Estimated H-index: 8
+ 9 AuthorsJulius Lukeš50
Estimated H-index: 50
Euglena gracilis is a well-studied biotechnologically exploitable phototrophic flagellate harbouring secondary green plastids. Here we describe its plastid proteome obtained by high-resolution proteomics. We identified 1,345 candidate plastid proteins and assigned functional annotations to 774 of them. More than 120 proteins are affiliated neither to the host lineage nor the plastid ancestor and may represent horizontal acquisitions from various algal and prokaryotic groups. Reconstruction of pl...
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Published on Feb 1, 2019in Trends in Microbiology 11.78
Vladimír Hampl21
Estimated H-index: 21
(Charles University in Prague),
Ivan Čepička19
Estimated H-index: 19
(Charles University in Prague),
Marek Eliáš27
Estimated H-index: 27
(University of Ostrava)
Arguments based on cell energetics favour the view that a mitochondrion capable of oxidative phosphorylation was a prerequisite for the evolution of other features of the eukaryotic cell, including increased volume, genome size and, eventually, phagotrophy. Contrary to this we argue that: (i) extant amitochondriate eukaryotes possess voluminous phagotrophic cells with large genomes; (ii) picoeukaryotes demonstrate that phagotrophy is feasible at prokaryotic cell sizes; and (iii) the assumption t...
1 Citations Source Cite
Published on Dec 1, 2018in Scientific Reports 4.12
Kristína Záhonová5
Estimated H-index: 5
(University of Ostrava),
Romana Petrželková3
Estimated H-index: 3
(University of Ostrava)
+ 13 AuthorsGertraud Burger42
Estimated H-index: 42
(Université de Montréal)
Rheb is a conserved and widespread Ras-like GTPase involved in cell growth regulation mediated by the (m)TORC1 kinase complex and implicated in tumourigenesis in humans. Rheb function depends on its association with membranes via prenylated C-terminus, a mechanism shared with many other eukaryotic GTPases. Strikingly, our analysis of a phylogenetically rich sample of Rheb sequences revealed that in multiple lineages this canonical and ancestral membrane attachment mode has been variously altered...
2 Citations Source Cite
Published on Nov 1, 2018in Protist 2.70
Sebastian C. Treitli2
Estimated H-index: 2
(Charles University in Prague),
Michael Kotyk2
Estimated H-index: 2
(Charles University in Prague)
+ 6 AuthorsVladimír Hampl21
Estimated H-index: 21
(Charles University in Prague)
Oxymonads are a group of flagellates living as gut symbionts of insects or vertebrates. They have several unique features, one of them being the absence of mitochondria. Diversity of this group is seriously understudied, which is particularly true for small species from the family Polymastigidae. We isolated 34 strains of oxymonads with Polymastigidae-like morphology from 24 host species and unused cesspits and sequenced the SSU rRNA gene. Our strains formed two clades in the phylogenetic tree w...
3 Citations Source Cite
Published on Sep 26, 2018in Journal of Eukaryotic Microbiology 2.54
Sina M. Adl18
Estimated H-index: 18
(University of Saskatchewan),
David Bass32
Estimated H-index: 32
(Centre for Environment, Fisheries and Aquaculture Science)
+ 44 AuthorsFabien Burki27
Estimated H-index: 27
(Science for Life Laboratory)
This revision of the classification of eukaryotes follows that of Adl et al., 2012 [J. Euk. Microbiol. 59(5)] and retains an emphasis on protists. Changes since have improved the resolution of many ...
15 Citations Source Cite
Published on Sep 1, 2018in Molecular Biology and Evolution 10.22
Vojtěch Vacek2
Estimated H-index: 2
(Charles University in Prague),
Lukáš Novák3
Estimated H-index: 3
(Charles University in Prague)
+ 5 AuthorsVladimír Hampl21
Estimated H-index: 21
(Charles University in Prague)
Source Cite
Published on Apr 1, 2018in Current Genetics 3.57
Lucia Hadariová2
Estimated H-index: 2
(Charles University in Prague),
Matej Vesteg9
Estimated H-index: 9
(Matej Bel University)
+ 1 AuthorsJuraj Krajčovič17
Estimated H-index: 17
Chloroplasts are generally known as eukaryotic organelles whose main function is photosynthesis. They perform other functions, however, such as synthesizing isoprenoids, fatty acids, heme, iron sulphur clusters and other essential compounds. In non-photosynthetic lineages that possess plastids, the chloroplast genomes have been reduced and most (or all) photosynthetic genes have been lost. Consequently, non-photosynthetic plastids have also been reduced structurally. Some of these non-photosynth...
7 Citations Source Cite
Published on Aug 14, 2017in Advances in Botanical Research 1.39
Anna M. G. Novák Vanclová2
Estimated H-index: 2
(Charles University in Prague),
Lucia Hadariová2
Estimated H-index: 2
(Charles University in Prague)
+ 1 AuthorsVladimír Hampl21
Estimated H-index: 21
(Charles University in Prague)
Abstract Euglenophytes obtained their plastids from a primary green alga related to extant genus Pyramimonas . The relatively recent establishment of this new organelle is an intriguing evolutionary phenomenon worth studying and comparing with other secondary plastids with a regard to their similarities and differences. A remarkably fast evolution driven by rapid intron gain and diversification is observed in euglenid plastid genomes which often tend to swell in size and rearrange while keeping ...
2 Citations Source Cite
Published on May 1, 2017in Journal of Eukaryotic Microbiology 2.54
Štěpánka Hrdá4
Estimated H-index: 4
(Charles University in Prague),
Miluše Hroudová9
Estimated H-index: 9
(Academy of Sciences of the Czech Republic)
+ 1 AuthorsVladimír Hampl21
Estimated H-index: 21
(Charles University in Prague)
Prasinophytes are a paraphyletic assemblage of nine heterogeneous lineages in the Chlorophyta clade of Archaeplastida. Until now, seven complete mitochondrial genomes have been sequenced from four prasinophyte lineages. Here we report the mitochondrial genome of Pyramimonas parkeae, the first respresentative of the prasinophyte clade I. The circular-mapping molecule is 43,294 bp long, AT rich (68.8%), very compact and it comprises two 6,671 bp long inverted repeat regions. The gene content is sl...
2 Citations Source Cite
Published on Dec 1, 2016in BMC Evolutionary Biology 3.03
Lukáš Novák3
Estimated H-index: 3
(Charles University in Prague),
Zuzana Zubáčová7
Estimated H-index: 7
(Charles University in Prague)
+ 8 AuthorsIvan Čepička19
Estimated H-index: 19
(Charles University in Prague)
Background Multiple prokaryotic lineages use the arginine deiminase (ADI) pathway for anaerobic energy production by arginine degradation. The distribution of this pathway among eukaryotes has been thought to be very limited, with only two specialized groups living in low oxygen environments (Parabasalia and Diplomonadida) known to possess the complete set of all three enzymes. We have performed an extensive survey of available sequence data in order to map the distribution of these enzymes amon...
4 Citations Source Cite
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