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Anna Asplund
Uppsala University
84Publications
28H-index
6,657Citations
Publications 84
Newest
Published on 2019in Molecular Systems Biology9.80
Dongxue Wang3
Estimated H-index: 3
(TUM: Technische Universität München),
Basak Eraslan1
Estimated H-index: 1
(LMU: Ludwig Maximilian University of Munich)
+ 7 AuthorsChen Meng7
Estimated H-index: 7
(TUM: Technische Universität München)
Genome-, transcriptome- and proteome-wide measurements provide insights into how biological systems are regulated. However, fundamental aspects relating to which human proteins exist, where they ar ...
Published on 2019in Molecular Systems Biology9.80
Basak Eraslan1
Estimated H-index: 1
(LMU: Ludwig Maximilian University of Munich),
Dongxue Wang3
Estimated H-index: 3
(TUM: Technische Universität München)
+ 7 AuthorsThomas A. Hopf10
Estimated H-index: 10
(TUM: Technische Universität München)
Despite their importance in determining protein abundance, a comprehensive catalogue of sequence features controlling protein-to-mRNA (PTR) ratios and a quantification of their effects are still la ...
Published on Dec 1, 2017in Nature Communications11.88
Sandra Andersson25
Estimated H-index: 25
,
Mårten Sundberg3
Estimated H-index: 3
+ 9 AuthorsOla Söderberg38
Estimated H-index: 38
Published on Jul 1, 2017in Endocrinology3.80
Sandra Andersson25
Estimated H-index: 25
,
Mårten Sundberg3
Estimated H-index: 3
+ 9 AuthorsOla Söderberg38
Estimated H-index: 38
Published on Sep 22, 2016in Thrombosis and Haemostasis4.73
Oskar Eriksson5
Estimated H-index: 5
,
Anna Asplund28
Estimated H-index: 28
+ 4 AuthorsAgneta Siegbahn63
Estimated H-index: 63
Colorectal cancer (CRC) is a major cause of morbidity and mortality, and the composition of the tumour stroma is a strong predictor of survival in this cancer type. Tissue factor (TF) functions as the trigger of haemostasis together with its ligand coagulation factor VII/VIIa, and TF expression has been found in tumour cells of colorectal tumours. However, TF expression in the CRC tumour stroma or its relationship to patient outcome has not yet been studied. To address this question we developed...
Published on May 1, 2016in Journal of Histochemistry and Cytochemistry2.37
Cecilia Lindskog19
Estimated H-index: 19
(Science for Life Laboratory),
Anna Asplund28
Estimated H-index: 28
(Uppsala University)
+ 2 AuthorsMichael Rützler16
Estimated H-index: 16
(AAU: Aalborg University)
AQP9 is known to facilitate hepatocyte glycerol uptake. Murine AQP9 protein expression has been verified in liver, skin, epididymis, epidermis and neuronal cells using knockout mice. Further expression sites have been reported in humans. We aimed to verify AQP9 expression in a large set of human normal organs, different cancer types, rheumatoid arthritis synovial biopsies as well as in cell lines and primary cells. Combining standardized immunohistochemistry with high-throughput mRNA sequencing,...
Published on Dec 1, 2015in Scientific Reports4.01
Nina Gustafsson Sheppard4
Estimated H-index: 4
,
Lisa Jarl1
Estimated H-index: 1
+ 8 AuthorsMohit Jain38
Estimated H-index: 38
Folate metabolism is central to cell proliferation and a target of commonly used cancer chemotherapeutics. In particular, the mitochondrial folate-coupled metabolism is thought to be important for proliferating cancer cells. The enzyme MTHFD2 in this pathway is highly expressed in human tumors and broadly required for survival of cancer cells. Although the enzymatic activity of the MTHFD2 protein is well understood, little is known about its larger role in cancer cell biology. We here report tha...
Published on Jul 1, 2015in Scientific Reports4.01
Pouyan Ghaffari4
Estimated H-index: 4
(Chalmers University of Technology),
Adil Mardinoglu27
Estimated H-index: 27
(Chalmers University of Technology)
+ 4 AuthorsJens B. Nielsen84
Estimated H-index: 84
(Chalmers University of Technology)
Human cancer cell lines are used as important model systems to study molecular mechanisms associated with tumor growth, hereunder how genomic and biological heterogeneity found in primary tumors affect cellular phenotypes. We reconstructed Genome scale metabolic models (GEMs) for eleven cell lines based on RNA-Seq data and validated the functionality of these models with data from metabolite profiling. We used cell line-specific GEMs to analyze the differences in the metabolism of cancer cell li...
Published on Jan 1, 2015
Sandra Andersson25
Estimated H-index: 25
,
Mårten Sundberg3
Estimated H-index: 3
+ 5 AuthorsAnna Asplund28
Estimated H-index: 28
Proteomics is a fast growing field and there has been a tremendous increase of knowledge the last two decades. Mass spectrometry is the most used method for analysis of complex protein samples. It can be used both in large scale discovery studies as well as in targeted quantitative studies. In parallel with the fast improvements of mass spectrometry-based proteomics there has been a fast growth of affinity-based methods. A common challenge is the large dynamic range of protein concentrations in ...
Published on Jan 1, 2015
Oskar Eriksson5
Estimated H-index: 5
,
Åsa Thulin7
Estimated H-index: 7
+ 3 AuthorsAgneta Siegbahn63
Estimated H-index: 63
Tissue Factor/coagulation factor VIIa potentiates ligand-dependent EphA2 signaling in cancer cells
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