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Chihiro Kida
Hoshi University
Organic chemistryChemistryEmulsionChromatographyRelaxation (NMR)
5Publications
3H-index
15Citations
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Publications 5
Newest
#1Terushi Ito (University of Toyama)
#2Chihiro Kida (Hoshi University)H-Index: 3
Last. Yoshinori Onuki (University of Toyama)H-Index: 15
view all 9 authors...
The purpose of the present study is to demonstrate the applicability of magnetic resonance imaging, especially T2 relaxation time mapping, for nondestructive monitoring of the dispersion state of nanoparticles (NPs) in concentrated suspensions. TiO2 15-nm-diameter NPs, for use in sunscreen lotion products, were examined as a test NP. First, this study investigated whether T2 is sensitive to the NP concentration. In experiments with pulsed nuclear magnetic resonance on TiO2 NP suspensions with di...
Source
#1Yoshinori Onuki (University of Toyama)H-Index: 15
#2Chihiro Kida (Hoshi University)H-Index: 3
Last. Kozo Takayama (Hoshi University)H-Index: 47
view all 5 authors...
We have recently established a novel method to evaluate the emulsion stability of pharmaceutical skin cream. The key technology of the method is magnetic resonance imaging (MRI). The purpose of this study was to verify the usefulness of the method in the cosmetic industry.Milky lotion-type emulsions were employed as test samples. We note that the test samples were prepared by taking account of commercial milky lotions. After the sample preparation, a centrifugation treatment (5000 g for up to 12...
6 CitationsSource
#1Yoshinori Onuki (Hoshi University)H-Index: 15
#2Naoki Hasegawa (Hoshi University)H-Index: 2
Last. Kozo Takayama (Hoshi University)H-Index: 47
view all 8 authors...
Background Significant precipitation produced by the dilution of diazepam (DZP) injection with an infusion fluid is a great concern for the clinical practice. In this study, the precipitation behavior under different conditions was investigated.
Source
#1Yoshinori Onuki (Hoshi University)H-Index: 15
#2Naoki Hasegawa (Hoshi University)H-Index: 2
Last. Kozo Takayama (Hoshi University)H-Index: 47
view all 8 authors...
The physical stability of pharmaceutical emulsions is an important quality attribute to be considered. To obtain a better understanding of this issue, this study investigated the contribution of the state of water to the physical stability of pharmaceutical emulsions. The key technology to evaluate the state of water was magnetic resonance imaging (MRI). For sample preparation, model emulsions with different formulation variables (surfactant content, water content, and hydrophilic-lipophilic bal...
4 CitationsSource
#1Yoshinori Onuki (Hoshi University)H-Index: 15
#2Naoki Hasegawa (Hoshi University)H-Index: 2
Last. Kozo Takayama (Hoshi University)H-Index: 47
view all 5 authors...
Photocrosslinked polyacrylic acid (PAA–HEMA) hydrogels are a promising candidate for use in dermatological patch adhesives. To gain further knowledge about the properties of this gel, we investigated the T 1 relaxation time and the diffusion coefficient ( D ) of water in the hydrogels using magnetic resonance (MR) imaging. Hydrogels with different formulations and process factors were prepared and tested. The observed data were analyzed by ANOVA, which clarified the mode of action of the formula...
5 CitationsSource
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