Match!
Elaine C. Seaver
University of Florida
54Publications
27H-index
3,563Citations
Publications 54
Newest
#1Marleen Klann (Whitney Laboratory for Marine Bioscience)
#2Elaine C. Seaver (Whitney Laboratory for Marine Bioscience)H-Index: 27
Abstract The transcription factor Pax6 is an important regulator of early animal development. Loss of function mutations of pax6 in a range of animals result in a reduction or complete loss of the eye, a reduction of a subset of neurons, and defects in axon growth. There are no studies focusing on the role of pax6 during development of any lophotrochozoan representative, however, expression of pax6 in the developing eye and nervous system in a number of species suggest that pax6 plays a highly c...
#1Marleen Klann (University of Sussex)
#2Elaine C. Seaver (UF: University of Florida)H-Index: 27
The transcription factor Pax6 is an important regulator of early animal development. Loss of function mutations of pax6 in a range of animals results in a reduction or complete loss of the eye, a reduction of a subset of neurons, and defects in axon growth. There are no studies focusing on the role of pax6 during development of any lophotrochozoan representative, however, expression of pax6 in the developing eye and nervous system in a number of species suggest that pax6 plays a highly conserved...
#1Leah C. DannenbergH-Index: 1
#2Leah C. Dannenberg (Whitney Laboratory for Marine Bioscience)
Last.Elaine C. SeaverH-Index: 27
view all 3 authors...
Abstract The germline is essential for sexual reproduction and survival of the species. In many metazoans, the developmental potential to generate a distinct germline is segregated from somatic cell lineages early in embryogenesis, suggesting that the unique features of the germline must be established from its onset. Previous studies suggest that germ cells cannot regenerate once removed from the embryo, but few animals have been experimentally tested. We investigated the ability of the germlin...
#1Danielle de Jong (Whitney Laboratory for Marine Bioscience)H-Index: 15
#2Elaine C. Seaver (Whitney Laboratory for Marine Bioscience)H-Index: 27
Many animals can regenerate, although there is great diversity in regenerative capabilities. A major question in regenerative biology is determining the cellular source of newly formed tissue. The polychaete annelid, Capitella teleta, can regenerate posterior segments following transverse amputation. However the source, behavior and molecular characteristics of the cells that form new tissue during regeneration are largely unknown. Using an indirect cell tracking method involving EdU incorporati...
#1Alexis R. Lanza (Whitney Laboratory for Marine Bioscience)
#2Elaine C. Seaver (Whitney Laboratory for Marine Bioscience)H-Index: 27
Abstract Embryonic organizers are signaling centers that coordinate developmental events within an embryo. Localized to either an individual cell or group of cells, embryonic organizing activity induces the specification of other cells in the embryo and can influence formation of body axes. In the spiralian Capitella teleta , previous cell deletion studies have shown that organizing activity is localized to a single cell, 2d, and this cell induces the formation of the dorsal-ventral axis and bil...
#1Abhinav Sur (Clark University)H-Index: 1
#2Craig R. Magie (Quinnipiac University)H-Index: 2
Last.Néva P. Meyer (Clark University)H-Index: 2
view all 4 authors...
Background How nervous systems evolved remains an unresolved question. Previous studies in vertebrates and arthropods revealed that homologous genes regulate important neurogenic processes such as cell proliferation and differentiation. However, the mechanisms through which such homologs regulate neurogenesis across different bilaterian clades are variable, making inferences about nervous system evolution difficult. A better understanding of neurogenesis in the third major bilaterian clade, Spir...
Spiralian development is characterized by stereotypic cell geometry and spindle orientation in early cleavage-stage embryos, and of ultimate fates of descendent clones. Diverse taxa such as molluscs, annelids, flatworms and nemerteans exhibit spiralian development, but it is a mystery how such a conserved developmental program gives rise to such diverse body plans. This review highlights examples of variation during early development among spiralians, emphasizing recent experimental studies in t...
#1Elaine C. Seaver (Whitney Laboratory for Marine Bioscience)H-Index: 27
Investigating development in a wide variety of organisms allows researchers to take advantage of both diverse and conserved evolutionary solutions that animals have made to solve a range of biological problems. Next generation sequencing and functional genomic techniques can now be applied to many animals, providing opportunities to study organisms whose biology offers advantages for tracking particular questions. Capitella teleta is an segmented annelid worm whose phylogenetic position, stable ...
#1Danielle de Jong (Whitney Laboratory for Marine Bioscience)H-Index: 15
#2Elaine C. Seaver (Whitney Laboratory for Marine Bioscience)H-Index: 27
Regeneration, the ability to replace lost tissues and body parts following traumatic injury, occurs widely throughout the animal tree of life. Regeneration occurs either by remodeling of pre-existing tissues, through addition of new cells by cell division, or a combination of both. We describe a staging system for posterior regeneration in the annelid, Capitella teleta, and use the C. teleta Hox gene code as markers of regional identity for regenerating tissue along the anterior-posterior axis. ...
#1Emi Yamaguchi (UH: University of Hawaii)H-Index: 4
#2Leah C. Dannenberg (UH: University of Hawaii)H-Index: 1
Last.Elaine C. Seaver (UH: University of Hawaii)H-Index: 27
view all 4 authors...
Abstract The stereotypic cleavage pattern shared by spiralian embryos provides unique opportunities to compare mechanisms of cell fate specification of homologous blastomeres, and can give insights into how changes in fate may have influenced the evolution of novel structures and morphological diversity. The potential of cells to undergo regulation and the timing of cell fate specification were investigated during early development in the polychaete annelid, Capitella teleta . Targeted laser del...
123456