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David J. Belton
Nottingham Trent University
25Publications
11H-index
727Citations
Publications 25
Newest
#1Graham J. Hickman (NTU: Nottingham Trent University)H-Index: 4
#2David J. Belton (NTU: Nottingham Trent University)H-Index: 11
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 46
view all 4 authors...
There is an increasing demand for environmentally sustainable sourcing of ingredients for the food, pharmaceutical and supplements industries. In the case of calcium carbonate (E170) as by-products from the egg and shellfish processing industries these have the potential to be sustainably sourced. In addition to their green credentials, biogenic carbonates have intrinsic benefits in terms of their chemical composition, such as a low heavy metal burden. However, their biogenic origin can potentia...
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#1David J. Belton (NTU: Nottingham Trent University)H-Index: 11
#2Graham J. Hickman (NTU: Nottingham Trent University)H-Index: 4
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 46
view all 3 authors...
ABSTRACTCalcium carbonate (E170) is a common food and pharmaceutical additive/ingredient. In addition to a source of calcium, the carbonate has uses including as a colour, acidity regulator and bulking agent. Globally, a range of regulatory agencies and pharmacopoeia control the analyses and specification of additives in food, supplements, pharmaceutical substances and excipients. Accordingly, a range of specifications and analyses exist for calcium carbonate depending on the application and mar...
1 CitationsSource
#1Dv Scholey (NTU: Nottingham Trent University)H-Index: 5
#2David J. Belton (NTU: Nottingham Trent University)H-Index: 11
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 46
view all 4 authors...
In this study, we assessed uptake and potential efficacy of a novel, pH neutral form of silicon supplement in vitro and using broiler chickens as a model species. In vitro bioavailability of this supplement was significantly higher than other commercial supplements tested, all of which claim available silica content. To confirm bioavailability of the new supplement in vivo, a broiler chick feeding trial reported blood uptake that was significantly higher than a Bamboo-derived silicon supplement....
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#1Victor V. Volkov (NTU: Nottingham Trent University)H-Index: 8
#2David J. Belton (NTU: Nottingham Trent University)H-Index: 11
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 46
view all 3 authors...
Structural properties of bioinorganic composites are of current interest in the areas of drug delivery, bone repair, and biomimetics. In such composite systems, structural analysis is enhanced when we combine methods of spectroscopy and simulation. Depending on size and shape, structural discontinuities of inorganic matter may modulate the optical response of a bound molecule. Using density functional theory, we explore the effects of a local field next to the surface of a silica cluster on freq...
1 CitationsSource
#1David J. Belton (NTU: Nottingham Trent University)H-Index: 11
#2Robyn Plowright (NTU: Nottingham Trent University)H-Index: 3
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 46
view all 4 authors...
Abstract The physical and mechanical properties of structural proteins such as silk fibroin can be modified by controlled conformational change, which is regularly monitored by Fourier transform infrared spectroscopy by peak fitting of the amide I band envelope. Although many variables affecting peak shape are well established, there is no fixed methodology to compare and follow secondary structural differences without significant operator input especially where low frequency spectral noise is a...
2 CitationsSource
#1Robyn Plowright (NTU: Nottingham Trent University)H-Index: 3
#2David J. Belton (NTU: Nottingham Trent University)H-Index: 11
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 46
view all 4 authors...
We present a non-destructive analytical calibration tool to allow quantitative assessment of individual calcium phosphates such as hydroxyapatite (HAP) from mixtures including brushite. Many experimental approaches are used to evaluate the mineralising capabilities of biomolecules including peptides. However, it is difficult to quantitatively compare the efficacy of peptides in the promotion of mineralisation when inseparable mixtures of different minerals are produced. To address this challenge...
1 CitationsSource
#1Nina Dinjaski (Tufts University)H-Index: 11
#2Robyn Plowright (NTU: Nottingham Trent University)H-Index: 3
Last.David L. Kaplan (Tufts University)H-Index: 149
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Abstract Protein polymers provide a unique opportunity for tunable designs of material systems due to the genetic basis of sequence control. To address the challenge of biomineralization interfaces with protein based materials, we genetically engineered spider silks to design organic-inorganic hybrid systems. The spider silk inspired domain (SGRGGLGGQG AGAAAAAGGA GQGGYGGLGSQGT) 15 served as an organic scaffold to control material stability and to allow multiple modes of processing, whereas the h...
10 CitationsSource
#1Anna Sola-Rabada (NTU: Nottingham Trent University)H-Index: 4
#2Julia Rinck (KIT: Karlsruhe Institute of Technology)H-Index: 8
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 46
view all 5 authors...
Silica is the second most abundant biomineral being exceeded in nature only by biogenic CaCO3. Many land plants (such as rice, cereals, cucumber, etc.) deposit silica in significant amounts to reinforce their tissues and as a systematic response to pathogen attack. One of the most ancient species of living vascular plants, Equisetum arvense is also able to take up and accumulate silica in all parts of the plant. Numerous methods have been developed for elimination of the organic material and/or ...
3 CitationsSource
#1Robyn Plowright (NTU: Nottingham Trent University)H-Index: 3
#2Nina Dinjaski (Tufts University)H-Index: 11
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 46
view all 6 authors...
Correction for ‘Influence of silk–silica fusion protein design on silica condensation in vitro and cellular calcification’ by Robyn Plowright et al., RSC Adv., 2016, 6, 21776–21788.
11 CitationsSource
1 CitationsSource
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