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W. Curt LaFrance
Brown University
Publications 110
Published on Aug 1, 2019in Journal of Cellular Physiology 4.52
Yan Cheng1
Estimated H-index: 1
Mandy Pereira10
Estimated H-index: 10
+ 10 AuthorsMaria Chiara Deregibus35
Estimated H-index: 35
Published on Mar 8, 2019in Journal of Neurology, Neurosurgery, and Psychiatry 8.27
Ibai Diez6
Estimated H-index: 6
Laura Ortiz-Terán4
Estimated H-index: 4
(Harvard University)
+ 7 AuthorsDavid L. Perez14
Estimated H-index: 14
(Harvard University)
Objective Some individuals with functional neurological disorder (FND) exhibit motor and affective disturbances, along with limbic hyper-reactivity and enhanced motor-limbic connectivity. Given that the multimodal integration network (insula, dorsal cingulate, temporoparietal junction (TPJ)) is implicated in convergent sensorimotor, affective and interoceptive processing, we hypothesised that patients with FND would exhibit altered motor and amygdalar resting-state propagation to this network. P...
Published on Aug 1, 2018in Psychosomatics 1.54
Rozita Jalilianhasanpour2
Estimated H-index: 2
(Harvard University),
Juan Pablo Ospina1
Estimated H-index: 1
(Harvard University)
+ 6 AuthorsDavid L. Perez14
Estimated H-index: 14
(Harvard University)
Background The relationships between baseline neuropsychiatric factors and clinical outcome in patients with functional neurological disorder (FND)/conversion disorder remain poorly understood. Objective This prospective, naturalistic pilot study investigated links between predisposing vulnerabilities (risk factors) and clinical outcome in patients with motor FND engaged in usual care within a subspecialty FND clinic. Methods Thirty-four patients with motor FND were enrolled and completed baseli...
Published on Jan 1, 2019in Seizure-european Journal of Epilepsy 2.77
Tanvir U. Syed13
Estimated H-index: 13
W. Curt LaFrance29
Estimated H-index: 29
(Rhode Island Hospital)
+ 12 AuthorsNasser Y Ali
Abstract Purpose We evaluate outcome of in-home diagnostic ambulatory video-EEG monitoring (AVEM) performed on a nationwide cohort of patients over one calendar year, and we compare our findings with outcomes of inpatient adult and pediatric VEM performed during the same year at two academic epilepsy centers. Methods This is a retrospective cohort study. We obtained AVEM outcome data from an independent ambulatory-EEG testing facility. Inpatient VEM data from a 4-bed adult epilepsy center and an...
Published on Nov 1, 2018in Journal of Neurology, Neurosurgery, and Psychiatry 8.27
David L. Perez14
Estimated H-index: 14
Benjamin F. Williams32
Estimated H-index: 32
(Harvard University)
+ 4 AuthorsMatchen S Keshavan94
Estimated H-index: 94
(BIDMC: Beth Israel Deaconess Medical Center)
Advancements in the management of FND emphasise a ‘rule-in’ diagnosis and roles for cognitive behavioural therapy (CBT)1 and physical therapy (PT).2 Neuroimaging studies have also started delineating the neuropathophysiology of FND.3 In the same cohort as this present study, we previously identified that impaired mental health and increased trait anxiety correlated with individual differences in amygdalar volume in patients with FND, while diminished physical functioning was associated with redu...
Published on Sep 1, 2018in JAMA Neurology 12.32
Alberto J. Espay35
Estimated H-index: 35
(UC: University of Cincinnati),
Selma Aybek12
Estimated H-index: 12
+ 12 AuthorsTimothy Nicholson17
Estimated H-index: 17
('KCL': King's College London)
Importance Functional neurological disorders (FND) are common sources of disability in medicine. Patients have often been misdiagnosed, correctly diagnosed after lengthy delays, and/or subjected to poorly delivered diagnoses that prevent diagnostic understanding and lead to inappropriate treatments, iatrogenic harm, unnecessary and costly evaluations, and poor outcomes. Observations Functional Neurological Symptom Disorder/Conversion Disorder was adopted by the Diagnostic and Statistical Manual ...
Published on Aug 1, 2018in Practical Neurology
Caitlin Adams3
Estimated H-index: 3
Jordan R. Anderson1
Estimated H-index: 1
(Brown University)
+ 2 AuthorsDavid L. Perez14
Estimated H-index: 14
Patients with functional neurological disorders (FND)/conversion disorder commonly present to outpatient clinics. FND is now a ‘rule in’ diagnosis based on neurological examination findings and semiological features. While neurologists may be more comfortable diagnosing patients with FND, there is only limited guidance as to how to conduct follow-up outpatient visits. Using clinical vignettes, we provide practical suggestions that may help guide clinical encounters including how to: (1) explore ...
Published on Jul 9, 2018in Journal of Pediatric Psychology 2.67
Brenda Bursch18
Estimated H-index: 18
(UCLA: University of California, Los Angeles),
Marcy Forgey4
Estimated H-index: 4
(UCLA: University of California, Los Angeles)
+ 12 AuthorsW. Curt LaFrance29
Estimated H-index: 29
(Brown University)