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Chadi Abbara
University of Angers
38Publications
4H-index
96Citations
Publications 39
Newest
#1G. Drevin (University of Angers)
#2M. Palayer (University of Angers)
Last.Chadi AbbaraH-Index: 4
view all 7 authors...
Purpose Yohimbine is an indole alkaloid extracted from the bark of the Pausinystalia yohimbe tree, which has found a clinical application through the treatment of erectile dysfunction. Yohimbine is also widely used by the bodybuilding community for its sympathomimetic effects and its presumed lipolytic effects. This substance is, however, associated with adverse effects, including cardiac and neurologic side-effects, but only few fatal cases have been described to date. In this context, this man...
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#2Youssef Daali (University of Geneva)H-Index: 26
Last.Xavier Declèves (Paris V: Paris Descartes University)H-Index: 13
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Abstract Background Several anatomic and physiologic changes occur after Roux-en-Y gastric bypass (RYGB) and its associated weight loss. At present, no single unified model can predict changes in drug metabolism associated with either RYGB surgery or weight loss. Objective The aim of this longitudinal human study was to measure the activity of the 5 most important Cytochrome P450 (CYP) involved in drug metabolism in patients with obesity before and after RYGB. Jejunal and liver biopsies obtained...
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Objectif D’apres les derniers chiffres du rapport de l’observatoire europeen des drogues et des toxicomanies (OEDT), la cocaine, generalement sous sa forme base, fait partie des produits stupefiants les plus saisis en Europe, la provenance etant le plus souvent l’Amerique du Sud. Depuis quelques annees, la purete des produits saisis a augmente : elle est passee de 22–57 % en 2008 [1] a 40–84 % en 2017 [2] . En parallele, les moyens utilises pour transporter la cocaine apparaissent de plus en plu...
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Objective Propofol is an intravenous anesthetic agent widely used in the induction and maintenance of general anesthesia. Acute intoxications with propofol are rare and remain primarily related to the acquisition of the product in hospital. If propofol can induce fatal respiratory depression alone, in a number of cases the clinical situation is exacerbated by the presence of other drugs like neuromuscular-blocking agents. Laudanosine, the circulating form of atracurium or cisatracurium, two non-...
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#2Camille Richeval (Lille University of Science and Technology)H-Index: 9
Last.Jean-Michel Gaulier (Lille University of Science and Technology)H-Index: 25
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Objective The consumption of new psychoactive substances (NPS), such as cathinones, has been on the rise over the last few years, with adverse effects ranging from agitation, anxiety and hallucinations to convulsions, severe cardiac, hepatic and renal failures [1] . This work aims to report and discuss a fatal case related to the concomitant use of two cathinone derivatives (CDs). Case history A 39-year-old man, known for drug addiction history, was found dead in his caravan. Multiple injection ...
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Objective Rapporter un cas de falsification d’un complement alimentaire utilise comme stimulant sexuel et achete sur internet. Cas Le centre antipoison et toxicovigilance du Grand Ouest (CAPTV) est contacte par un homme de 53 ans apres consommation d’un complement alimentaire utilise comme stimulant sexuel. Le produit s’est revele d’une telle efficacite que ce consommateur regulier de tadalafil s’interroge quant a sa reelle composition. Ce produit n’est disponible que sur internet et y est prese...
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#1M. DeguigneH-Index: 4
#2M. BrunetH-Index: 2
Last.Bénédicte LelièvreH-Index: 6
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AbstractObjective: We report two cases of elevated digoxin plasma levels in patients receiving enzalutamide.Cases reported: The first patient, an 84-year-old male treated with enzalutamide, was hospitalized due to deterioration in his general state. Atrial fibrillation was discovered and treatment with digoxin was initiated. Supratherapeutic digoxin concentrations (4 µg/L and 3.5 µg/L 3 days later) led to treatment being stopped despite the lack of clinical or biological signs of overdose. The s...
2 CitationsSource
#1Guillaume Churlaud (University of Paris)H-Index: 8
#2Chadi Abbara (University of Angers)H-Index: 4
Last.David Klatzmann (University of Paris)H-Index: 63
view all 9 authors...
2 CitationsSource
Objectif Rapporter un cas d’intoxication familiale avec syndrome anticholinergique apres ingestion de galettes preparees a partir de farine de sarrasin biologique et presenter l’interet du dosage de l’atropine et de la scopolamine dans la farine pour objectiver l’importance de la contamination. Methodes/Description du cas Le Centre antipoison est contacte par le medecin traitant d’une famille de 2 adultes et 3 enfants âges de 5, 6 et 9 ans (20,5–21,7 et 28,6 kg) qui ont consomme des galettes de ...
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#2J.-F. WiartH-Index: 4
Last.D. BoelsH-Index: 3
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Objectif Rapporter l’interet de l’apport analytique dans le diagnostic et la prise en charge d’une intoxication avec un insecticide organophosphore devant un tableau clinique peu contributif. Description du cas Une femme de 51 ans est hospitalisee apres ingestion volontaire d’un insecticide organophosphore (375 mL de chlorpyriphos methyl [CHLOM]) (Nuvagrain ® ), d’ethanol et de medicaments : tramadol, etodolac, diazepam et acide valproique. A sa prise en charge, l’aspiration gastrique permet de ...
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