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Timo A. Lakka
University of Eastern Finland
304Publications
73H-index
22.5kCitations
Publications 304
Newest
Andrew O. Agbaje1
Estimated H-index: 1
(University of Eastern Finland),
Eero A. Haapala8
Estimated H-index: 8
(University of Jyväskylä)
+ 6 AuthorsTimo A. Lakka73
Estimated H-index: 73
(University of Eastern Finland)
1 Citations Source Cite
Juuso Väistö7
Estimated H-index: 7
(University of Eastern Finland),
Eero A. Haapala8
Estimated H-index: 8
(University of Jyväskylä)
+ 9 AuthorsUlf Ekelund46
Estimated H-index: 46
(University of Cambridge)
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Merja R. Häkkinen11
Estimated H-index: 11
(University of Eastern Finland),
Teemu J. Murtola13
Estimated H-index: 13
(University of Tampere)
+ 6 AuthorsSeppo Auriola37
Estimated H-index: 37
(University of Eastern Finland)
Abstract This study describes a validated LC–MS/MS method for assaying 23 steroids within a single run from 150 μl of human plasma, serum or prostatic tissue homogenate. Isotope-labeled steroids were used as internal standards. Samples were extracted with toluene, and ketosteroids were derivatized with hydroxylamine prior to LC–MS/MS analysis. The steroids were separated on a C18 column and methanol was used as an organic solvent with the addition of 0.2 mM ammonium fluoride to improve underivat...
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Published on Jan 9, 2019in Pediatric Exercise Science 1.35
Andrew O. Agbaje1
Estimated H-index: 1
(University of Eastern Finland),
Eero A. Haapala8
Estimated H-index: 8
(University of Jyväskylä)
+ 7 AuthorsTimo A. Lakka73
Estimated H-index: 73
(University of Eastern Finland)
Purpose: To investigate the associations of directly measured peak oxygen uptake (V˙O2peak) and body fat percentage (BF%) with arterial stiffness and arterial dilatation capacity in children. Methods: Findings are based on 329 children (177 boys and 152 girls) aged 8–11 years. V˙O2peak was assessed by a maximal cardiopulmonary exercise test on a cycle ergometer and scaled by lean body mass (LM). BF% and LM were measured by bioelectrical impedance. Stiffness index (measure of arterial stiffness) ...
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Published on Jan 15, 2019in Human Brain Mapping 4.93
Sara Määttä18
Estimated H-index: 18
(University of Eastern Finland),
Laura Säisänen16
Estimated H-index: 16
(University of Eastern Finland)
+ 7 AuthorsMervi Könönen33
Estimated H-index: 33
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Published on Oct 1, 2018in Medicine and Science in Sports and Exercise 4.29
Eero A. Haapala8
Estimated H-index: 8
,
Niina Lintu9
Estimated H-index: 9
+ 8 AuthorsTomi Laitinen38
Estimated H-index: 38
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Published on Jun 19, 2018in Journal of Alzheimer's Disease 3.17
Eero A. Haapala8
Estimated H-index: 8
(University of Jyväskylä),
Jussi Paananen20
Estimated H-index: 20
(University of Eastern Finland)
+ 1 AuthorsTimo A. Lakka73
Estimated H-index: 73
(University of Eastern Finland)
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Published on Jun 18, 2018in PLOS ONE 2.77
Mary F. Feitosa31
Estimated H-index: 31
(Washington University in St. Louis),
Aldi T. Kraja33
Estimated H-index: 33
(Washington University in St. Louis)
+ 268 AuthorsXueling Sim40
Estimated H-index: 40
(National University of Singapore)
Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for gene-alcohol consumption interaction for BP might identify additional BP loci and contribute to the understanding of alcohol-related BP regulation. We conducted a large two-stage investigation incorporating joint testing of main genetic effects and single nucl...
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Published on Jan 1, 2018in Nature Genetics 27.13
Valérie Turcot5
Estimated H-index: 5
(Université de Montréal),
Yingchang Lu26
Estimated H-index: 26
(Icahn School of Medicine at Mount Sinai)
+ 397 AuthorsMariaelisa Graff19
Estimated H-index: 19
(University of North Carolina at Chapel Hill)
Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal genes remains challenging. Here we combined data from 718,734 individuals to discover rare and low-frequency (minor allele frequency (MAF) < 5%) coding variants associated with BMI. We identified 14 coding variants in 13 genes, of which 8 variants were in genes (Z...
38 Citations Source Cite
Published on Jan 1, 2018in American Journal of Human Genetics 8.86
Carolina Medina-Gomez23
Estimated H-index: 23
(Erasmus University Rotterdam),
John P. Kemp39
Estimated H-index: 39
(University of Bristol)
+ 86 AuthorsDaniel S. Evans22
Estimated H-index: 22
(California Pacific Medical Center)
Bone mineral density (BMD) assessed by DXA is used to evaluate bone health. In children, total body (TB) measurements are commonly used; in older individuals, BMD at the lumbar spine (LS) and femoral neck (FN) is used to diagnose osteoporosis. To date, genetic variants in more than 60 loci have been identified as associated with BMD. To investigate the genetic determinants of TB-BMD variation along the life course and test for age-specific effects, we performed a meta-analysis of 30 genome-wide ...
6 Citations Source Cite
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