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Stephen A. Lauer
Johns Hopkins University
OutbreakPublic healthInfectious disease (medical specialty)Dengue feverMedicine
33Publications
10H-index
950Citations
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Publications 34
Newest
#1Anita S Iyer (Harvard University)
#2Forrest K. Jones (Johns Hopkins University)H-Index: 5
Last. Wilfredo F. Garcia-Beltran (Harvard University)H-Index: 6
view all 35 authors...
BACKGROUND Characterizing the humoral immune response to SARS-CoV-2 and developing accurate serologic assays are needed for diagnostic purposes and estimating population-level seroprevalence. METHODS We measured the kinetics of early antibody responses to the receptor-binding domain (RBD) of the spike (S) protein of SARS-CoV-2 in a cohort of 259 symptomatic North American patients infected with SARS-CoV-2 (up to 75 days after symptom onset) compared to antibody levels in 1548 individuals whose b...
Source
#1Javier Perez-Saez (University of Geneva)H-Index: 1
#2Stephen A. Lauer (Johns Hopkins University)H-Index: 10
Last. Isabelle Arm-VernezH-Index: 2
view all 102 authors...
Source
#1Shaun A TrueloveH-Index: 13
#2Orit Abrahim (Johns Hopkins University)H-Index: 1
Last. Paul Spiegel (Johns Hopkins University)H-Index: 30
view all 7 authors...
Background COVID-19 could have even more dire consequences in refugees camps than in general populations. Bangladesh has confirmed COVID-19 cases and hosts almost 1 million Rohingya refugees from Myanmar, with 600,000 concentrated in the Kutupalong-Balukhali Expansion Site (mean age, 21 years; standard deviation [SD], 18 years; 52% female). Projections of the potential COVID-19 burden, epidemic speed, and healthcare needs in such settings are critical for preparedness planning. Methods and findi...
5 CitationsSource
#1Javier Perez-Saez (Johns Hopkins University)H-Index: 1
#2Stephen A. Lauer (Johns Hopkins University)H-Index: 10
Last. Andrew S. Azman (Johns Hopkins University)H-Index: 22
view all 8 authors...
The infection fatality risk (IFR) is the average number of deaths per infection by a pathogen and is key to characterizing the severity of infection across the population and for specific demographic groups. To date, there are few empirical estimates of IFR published due to challenges in measuring infection rates. Outside of closed, closely surveilled populations where infection rates can be monitored through viral surveillance, we must rely on indirect measures of infection, like specific antib...
1 CitationsSource
#1Joseph Lemaitre (EPFL: École Polytechnique Fédérale de Lausanne)H-Index: 4
#2Kyra H. Grantz (Johns Hopkins University)H-Index: 4
Last. Kathryn KaminskyH-Index: 1
view all 13 authors...
Coronavirus disease 2019 (COVID-19) has caused strain on health systems worldwide due to its high mortality rate and the large portion of cases requiring critical care and mechanical ventilation. During these uncertain times, public health decision makers, from city health departments to federal agencies, sought the use of epidemiological models for decision support in allocating resources, developing non-pharmaceutical interventions, and characterizing the dynamics of COVID-19 in their jurisdic...
1 CitationsSource
#1Silvia Stringhini (Geneva College)H-Index: 25
#2Ania Wisniak (University of Geneva)H-Index: 2
Last. Kailing Marcus (Geneva College)H-Index: 2
view all 25 authors...
Summary Background Assessing the burden of COVID-19 on the basis of medically attended case numbers is suboptimal given its reliance on testing strategy, changing case definitions, and disease presentation. Population-based serosurveys measuring anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) antibodies provide one method for estimating infection rates and monitoring the progression of the epidemic. Here, we estimate weekly seroprevalence of anti-SARS-CoV-2 antibodies in t...
11 CitationsSource
#1Stephen A. LauerH-Index: 10
Last. Nicholas G. ReichH-Index: 24
view all 3 authors...
Forecasting transmission of infectious diseases, especially for vector-borne diseases, poses unique challenges for researchers. Behaviors of and interactions between viruses, vectors, hosts, and the environment each play a part in determining the transmission of a disease. Public health surveillance systems and other sources provide valuable data that can be used to accurately forecast disease incidence. However, many aspects of common infectious disease surveillance data are imperfect: cases ma...
1 Citations
#1Shaun A Truelove (Johns Hopkins University)H-Index: 13
#2Orit Abrahim (Johns Hopkins University)H-Index: 1
Last. Paul Spiegel (Johns Hopkins University)H-Index: 30
view all 6 authors...
Background: COVID-19 could have even more dire consequences in refugees camps than in general populations. Bangladesh has confirmed COVID-19 cases and hosts almost 1 million Rohingya refugees from Myanmar with 600,000 concentrated in Kutupalong-Balukhali Expansion Site (age mean: 21 years, sd: 18 years, 52% female). Projections of the potential COVID-19 burden, epidemic speed, and healthcare needs in such settings are critical for preparedness planning. Methods and Findings: To explore the poten...
1 CitationsSource
#1Lauren M. Kucirka (Johns Hopkins University)H-Index: 29
#2Stephen A. Lauer (Johns Hopkins University)H-Index: 10
Last. Justin Lessler (Johns Hopkins University)H-Index: 43
view all 5 authors...
Tests for severe acute respiratory syndrome coronavirus 2 based on reverse transcriptase polymerase chain reaction (RT-PCR) are being used to “rule out” infection among high-risk persons, such as e...
25 CitationsSource
#1Silvia Stringhini (UNIL: University of Lausanne)H-Index: 25
#2Ania Wisniak (University of Geneva)H-Index: 2
Last. Kailing Marcus (Geneva College)H-Index: 2
view all 25 authors...
Background: Assessing the burden of COVID-19 based on medically-attended case counts is suboptimal given its reliance on testing strategy, changing case definitions and the wide spectrum of disease presentation. Population-based serosurveys provide one avenue for estimating infection rates and monitoring the progression of the epidemic, overcoming many of these limitations. Methods: Taking advantage of a pool of adult participants from population-representative surveys conducted in Geneva, Switz...
6 CitationsSource
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