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Robert W. Wysocki
Rush University Medical Center
SurgerySaccharomyces cerevisiaeBiochemistryMedicineBiology
120Publications
28H-index
2,979Citations
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Index finger metacarpophalangeal (MCP) joint arthrodesis is a potential reconstructive option for recalcitrant MCP arthritis. Due to lateral forces applied by the thumb, our institutional experience supports index finger MCP arthrodesis as a successful option in younger, higher demand patients and in the setting of significant joint instability. We present our technique of performing index finger MCP arthrodesis using a dorsal locking plate. The proposed benefits of this technique include the ab...
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#1Nitin Goyal (Rush University Medical Center)H-Index: 1
#2Faisal Akram (Rush University Medical Center)
Last. Robert W. Wysocki (Rush University Medical Center)H-Index: 28
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#1Timothy J. Luchetti (Rush University Medical Center)H-Index: 4
#2Robert W. Wysocki (Rush University Medical Center)H-Index: 28
Last. Mark S. Cohen (Rush University Medical Center)H-Index: 66
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Background: En bloc resection of the distal radius is a common treatment for advanced and recurrent giant cell tumors and less commonly for sarcoma. Various reconstructive options exist, including ulnar transposition, osteoarticular autograft and allograft, and allograft arthrodesis. We present a technique of reconstruction using a distal radius bulk allograft with a step-cut to allow for precise restoration of proper length and to promote bony union. Methods: Preoperative templating is performe...
1 CitationsSource
#1Nitin Goyal (Rush University Medical Center)H-Index: 1
#2Andrew G. Tsai (Rush University Medical Center)
Last. Robert W. Wysocki (Rush University Medical Center)H-Index: 28
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#1Donata Wawrzycka (UWr: University of Wrocław)H-Index: 6
#2Joanna Sadlak (UWr: University of Wrocław)
Last. Robert W. Wysocki (UWr: University of Wrocław)H-Index: 28
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Abstract The yeast plasma membrane transporter Acr3 mediates efflux of toxic arsenite and antimonite. Here, we investigated the mechanisms of Acr3 turnover. We found that after arrival and residence at the plasma membrane, Acr3 is subjected to internalization followed by proteolysis in the vacuole. Endocytic degradation of Acr3 is promoted by the ubiquitin ligase Rsp5 and requires polyubiquitination of Acr3 at multiple lysine residues via lysine 63-linked ubiquitin chains. The turnover of Acr3 a...
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#1Brian R. Waterman (Wake Forest University)H-Index: 30
#2Robert Dean (UIC: University of Illinois at Chicago)H-Index: 1
Last. Nikhil N. Verma (Rush University Medical Center)H-Index: 43
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#1Ewa Maciaszczyk-Dziubinska (UWr: University of Wrocław)H-Index: 9
#2Anna Reymer (University of Gothenburg)H-Index: 8
Last. Robert W. Wysocki (UWr: University of Wrocław)H-Index: 28
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Activator protein 1 (AP-1) is one of the largest families of basic leucine zipper (bZIP) transcription factors in eukaryotic cells. How AP-1 proteins achieve target DNA binding specificity remains elusive. In Saccharomyces cerevisiae, the AP-1-like protein (Yap) family comprises eight members (Yap1 to Yap8) that display distinct genomic target sites despite high sequence homology of their DNA binding bZIP domains. In contrast to the other members of the Yap family, which preferentially bind to s...
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#1Nitin Goyal (Rush University Medical Center)H-Index: 1
#2Daniel D. Bohl (Rush University Medical Center)H-Index: 23
Last. Robert W. Wysocki (Rush University Medical Center)H-Index: 28
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Background Open injuries communicating with the wrist joint are essential to detect to facilitate timely, appropriate treatment. While the saline load test to detect traumatic arthrotomy has been well studied in the knee and ankle, it has not been studied in the wrist, and therefore the appropriate volume of saline infusion to detect traumatic arthrotomy is not known. Purpose The purpose of this study was to utilize wrist arthroscopy to determine the saline infusion volume necessary to achieve 9...
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