Match!
Katarzyna Sitnik
Technical University of Denmark
12Publications
7H-index
292Citations
Publications 12
Newest
Published on Jun 20, 2019in PLOS Pathogens6.46
Nico A. Contreras2
Estimated H-index: 2
(UA: University of Arizona),
Katarzyna Sitnik7
Estimated H-index: 7
+ 3 AuthorsJanko Nikolich-Žugich17
Estimated H-index: 17
(UA: University of Arizona)
Cytomegalovirus (CMV) is a ubiquitous herpesvirus infecting most of the world’s population. CMV has been rigorously investigated for its impact on lifelong immunity and potential complications arising from lifelong infection. A rigorous adaptive immune response mounts during progression of CMV infection from acute to latent states. CD8 T cells, in large part, drive this response and have very clearly been demonstrated to take up residence in the salivary gland and lungs of infected mice during l...
Published on Jul 15, 2018in Journal of Immunology4.72
Kerstin Wendland1
Estimated H-index: 1
(Lund University),
Kristoffer Niss1
Estimated H-index: 1
(Novo Nordisk Foundation)
+ 10 AuthorsGeorg A. Holländer37
Estimated H-index: 37
(University of Oxford)
Despite the essential role of thymic epithelial cells (TEC) in T cell development, the signals regulating TEC differentiation and homeostasis remain incompletely understood. In this study, we show a key in vivo role for the vitamin A metabolite, retinoic acid (RA), in TEC homeostasis. In the absence of RA signaling in TEC, cortical TEC (cTEC) and CD80 lo MHC class II lo medullary TEC displayed subset-specific alterations in gene expression, which in cTEC included genes involved in epithelial pro...
Published on Aug 2, 2017in Journal of Immunology4.72
Lisa Borkner5
Estimated H-index: 5
,
Katarzyna Sitnik7
Estimated H-index: 7
+ 4 AuthorsLuka Cicin-Sain19
Estimated H-index: 19
Experimental CMV-based vaccine vectors expressing a single MHC class I–restricted high-avidity epitope provided strong, T cell–dependent protection against viruses or tumors. In this study we tested the low-avidity epitope KCSRNRQYL, and show that a mouse CMV (MCMV) vector provides complete immune control of recombinant vaccinia virus expressing the same epitope if KCSRNRQYL is expressed within the immediate-early MCMV gene ie2 . The same epitope expressed within the early M45 gene provided no p...
Published on Jan 1, 2017
Kerstin Wendland1
Estimated H-index: 1
(Lund University),
Katarzyna Sitnik7
Estimated H-index: 7
+ 2 AuthorsWilliam W. Agace47
Estimated H-index: 47
(National Veterinary Institute)
Published on Apr 1, 2016in Immunity21.52
K. Luda2
Estimated H-index: 2
(Lund University),
Thorsten Joeris11
Estimated H-index: 11
(DTU: Technical University of Denmark)
+ 13 AuthorsLisa Richter5
Estimated H-index: 5
(Oslo University Hospital)
Summary The role of dendritic cells (DCs) in intestinal immune homeostasis remains incompletely defined. Here we show that mice lacking IRF8 transcription-factor-dependent DCs had reduced numbers of T cells in the small intestine (SI), but not large intestine (LI), including an almost complete absence of SI CD8αβ + and CD4 + CD8αα + T cells; the latter requiring β8 integrin expression by migratory IRF8 dependent CD103 + CD11b - DCs. SI homing receptor induction was impaired during T cell priming...
Published on Mar 1, 2016in Cell Reports7.82
Katarzyna Sitnik7
Estimated H-index: 7
(DTU: Technical University of Denmark),
Kerstin Wendland1
Estimated H-index: 1
(Lund University)
+ 5 AuthorsWilliam W. Agace47
Estimated H-index: 47
(DTU: Technical University of Denmark)
Despite the key role of primary and secondary lymphoid organ stroma in immunity, our understanding of the heterogeneity and ontogeny of these cells remains limited. Here, we identify a functionally distinct subset of BP3(-)PDPN(+)PDGFRβ(+)/α(+)CD34(+) stromal adventitial cells in both lymph nodes (LNs) and thymus that is located within the vascular niche surrounding PDPN(-)PDGFRβ(+)/α(-)Esam-1(+)ITGA7(+) pericytes. CD34(+) adventitial cells developed in late embryonic thymus and in postnatal LNs...
Published on Feb 1, 2015in European Journal of Immunology4.70
Beth Lucas5
Estimated H-index: 5
(University of Birmingham),
Andrea J. White20
Estimated H-index: 20
(University of Birmingham)
+ 6 AuthorsAntal Rot45
Estimated H-index: 45
(Ebor: University of York)
Thymus colonisation and thymocyte positioning are regulated by interactions between CCR7 and CCR9, and their respective ligands, CCL19/CCL21 and CCL25. The ligands of CCR7 and CCR9 also interact with the atypical receptor CCRL1 (also known as ACKR4), which is expressed in the thymus and has recently been reported to play an important role in normal alpha beta T-cell development. Here, we show that CCRL1 is expressed within the thymic cortex, predominantly by MHC-II(low)CD40(-) cortical thymic ep...
Published on Jan 1, 2015
Katarzyna Sitnik7
Estimated H-index: 7
(Lund University),
Kerstin Wendland1
Estimated H-index: 1
(Lund University)
+ 5 AuthorsWilliam W. Agace47
Estimated H-index: 47
(National Veterinary Institute)
12