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Maria C. Rodriguez-Oroz
Ikerbasque
94Publications
32H-index
6,546Citations
Publications 94
Newest
Published on Mar 1, 2019in Neurobiology of Aging 4.40
Haritz Jiménez-Urbieta4
Estimated H-index: 4
,
Belén Gago11
Estimated H-index: 11
+ 9 AuthorsConcepció Marin24
Estimated H-index: 24
Abstract Treatment with dopaminergic agonists like Pramipexole (PPX) contributes to the development of impulse control disorders (ICDs) in patients with Parkinson’s disease (PD). As such, animal models of abnormal impulse control in PD are needed to better study the pathophysiology of these behaviors. Thus, we investigated impulsivity and related behaviors using the 5-Choice Serial Reaction Time Task (5-CSRTT), as well as FosB/ΔFosB expression, in rats with mild parkinsonism induced by viral-med...
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Published on Feb 1, 2019in Brain Imaging and Behavior 3.42
Carmen Gasca-Salas5
Estimated H-index: 5
(University of Navarra),
Daniel García-Lorenzo17
Estimated H-index: 17
(University of Paris)
+ 4 AuthorsMaria C. Rodriguez-Oroz32
Estimated H-index: 32
Mild cognitive impairment (MCI) in Parkinson’s disease (PD) is a risk factor for dementia and thus, it is of interest to elucidate if specific patterns of atrophy in PD-MCI patients are associated with a higher risk of developing dementia. We aim to define pattern(s) of regional atrophy in PD-MCI patients who developed dementia during 31 months of follow-up using cortical thickness analysis Twenty-three PD-MCI patients and 18 controls underwent brain MRI and completed a neuropsychological examin...
5 Citations Source Cite
Published on Dec 1, 2018in Scientific Reports 4.01
Alejandra Valderrama-Carvajal3
Estimated H-index: 3
(UMA: University of Málaga),
Haritz Irizar1
Estimated H-index: 1
(UCL: University College London)
+ 5 AuthorsAlicia Rivera28
Estimated H-index: 28
(UMA: University of Málaga)
Morphine binding to opioid receptors, mainly to μ opioid receptor (MOR), induces alterations in intracellular pathways essential to the initial development of addiction. The activation of the dopamine D4 receptor (D4R), which is expressed in the caudate putamen (CPu), mainly counteracts morphine-induced alterations in several molecular networks. These involve transcription factors, adaptive changes of MOR signaling, activation of the nigrostriatal dopamine pathway and behavioural effects, underl...
1 Citations Source Cite
Published on Nov 1, 2018in Movement Disorders 8.06
Manuel Delgado-Alvarado5
Estimated H-index: 5
,
Rosalía Dacosta‐Aguayo2
Estimated H-index: 2
+ 7 AuthorsMaria C. Rodriguez-Oroz32
Estimated H-index: 32
2 Citations Source Cite
Published on Nov 1, 2018in Movement Disorders 8.06
Jeroen Hoogland3
Estimated H-index: 3
,
Lennard L. van Wanrooij2
Estimated H-index: 2
+ 25 AuthorsCarme Junqué64
Estimated H-index: 64
(University of Barcelona)
© 2018 International Parkinson and Movement Disorder Society Background: Numerous neuropsychological tests and test versions are used in Parkinson's disease research, but their relative capacity to detect mild cognitive deficits and their comparability across studies are unknown. The objective of this study was to identify neuropsychological tests that consistently detect cognitive decline in PD across studies. Methods: Data from 30 normed neuropsychological tests across 20 international studies...
2 Citations Source Cite
Published on Oct 1, 2018in Neurobiology of Aging 4.40
Monica Diez-Fairen1
Estimated H-index: 1
(ISCIII: Instituto de Salud Carlos III),
Bruno A. Benitez15
Estimated H-index: 15
(WashU: Washington University in St. Louis)
+ 11 AuthorsMaria C. Rodriguez-Oroz32
Estimated H-index: 32
(Ikerbasque)
Abstract Eighteen loci and several susceptibility genes have been related to Parkinson's disease (PD). However, most studies focus on single genes in small PD series. Our aim was to establish the genetic background of a large Spanish PD sample. Pooled-DNA target sequencing of 7 major PD genes ( SNCA , PARK2 , PINK1 , DJ-1 , LRRK2 , GBA , and MAPT ) was performed in 562 PD cases. Forty-four variants were found among 114 individuals (20.28%, p PARK2 and PINK1 genes, whereas SNCA and DJ-1 variants ...
1 Citations Source Cite
Published on Jun 1, 2018in Journal of Neurology, Neurosurgery, and Psychiatry 8.27
Rafael Rodriguez-Rojas3
Estimated H-index: 3
(CEU San Pablo University),
Maylen Carballo-Barreda1
Estimated H-index: 1
+ 6 AuthorsJose A. Obeso15
Estimated H-index: 15
(CEU San Pablo University)
Objective Subthalamotomy is an effective alternative for the treatment of Parkinson’s disease (PD). However, uncertainty about the optimal target location and the possibility of inducing haemichorea-ballism have limited its application. We assessed the correlation between the topography of radiofrequency-based lesions of the subthalamic nucleus (STN) with motor improvement and the emergence of haemichorea-ballism. Methods Sixty-four patients with PD treated with subthalamotomy were evaluated pre...
2 Citations Source Cite
Published on Dec 1, 2017in Parkinsonism & Related Disorders 4.36
Carlos Estévez-Fraga1
Estimated H-index: 1
,
Jose Luis López-Sendón Moreno2
Estimated H-index: 2
+ 11 AuthorsMonica M. Kurtis13
Estimated H-index: 13
• Feeding dystonia, trunk spasms, head-drops and orolingual mutilations are distinctive features of ChAc.
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