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Giovanni Marchegiani
University of Verona
SurgeryPancreasPancreatic fistulaGeneral surgeryMedicine
208Publications
19H-index
1,998Citations
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Publications 229
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#1Roberto Salvia (University of Verona)H-Index: 37
#2Giovanni Marchegiani (University of Verona)H-Index: 19
Last. Salvatore Paiella (University of Verona)H-Index: 11
view all 12 authors...
BACKGROUND The application of postoperative pancreatic fistula (POPF) risk stratification and mitigation strategies requires an update of the protocol for an early drain removal after pancreaticoduodenectomy (PD). The aim of the study is to highlight the unreliability of a single drain fluid amylase (DFA) cutoff-based protocol in the setting of a risk-based drain management. METHODS The role of postoperative day one (POD1) DFA in predicting POPF was explored in the setting of both selective drai...
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#1Stijn van Roessel (UvA: University of Amsterdam)H-Index: 2
#2Marin Strijker (UvA: University of Amsterdam)H-Index: 4
Last. Marc G. Besselink (UvA: University of Amsterdam)H-Index: 50
view all 28 authors...
Abstract Background The objective of this study was to validate and update the Amsterdam prediction model including tumor grade, lymph node ratio, margin status and adjuvant therapy, for prediction of overall survival (OS) after pancreatoduodenectomy for pancreatic cancer. Methods We included consecutive patients who underwent pancreatoduodenectomy for pancreatic cancer between 2000 and 2017 at 11 tertiary centers in 8 countries (USA, UK, Germany, Italy, Sweden, the Netherlands, Korea, Australia...
1 CitationsSource
#1Raffaele PezzilliH-Index: 31
#2E. BuscariniH-Index: 38
Last. Gioia PozzaH-Index: 3
view all 45 authors...
Abstract Introduction A prospective survey to evaluate the diagnostic workup of cystic pancreatic neoplasms (CPNs) according to the Italian guidelines. Methods An online data sheet was built. Results Fifteen of the 1385 patients (1.1%) had non cystic neoplastic lesions. Forty percent (518/1295) had at least one 1st degree relative affected by a solid tumor of the digestive and extra-digestive organs. Symptoms/signs associated with the cystic lesion were present in 24.5% of the patients. The cyst...
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#1Giuseppe Malleo (University of Verona)H-Index: 29
#2Laura Maggino (University of Verona)H-Index: 10
Last. Keith D. Lillemoe (Harvard University)H-Index: 96
view all 13 authors...
BACKGROUND: The authors hypothesized that in resected pancreatic adenocarcinoma (PDAC), pathologic characteristics, oncologic outcomes, prognostic factors, and the accuracy of the American Joint Committee on Cancer (AJCC) staging system might differ based on tumor location. METHODS: Patients undergoing pancreatectomy for PDAC at two academic institutions from 2000 to 2015 were retrieved. A comparative analysis between head (H-PDAC) and body-tail (BT-PDAC) tumors was performed using uni- and mult...
1 CitationsSource
#1Giuseppe Malleo (University of Verona)H-Index: 29
#2Laura Maggino (University of Verona)H-Index: 10
Last. Giovanni Marchegiani (University of Verona)H-Index: 19
view all 12 authors...
Abstract Background The pattern of nodal spread in body-tail pancreatic ductal adenocarcinoma (PDAC) has been poorly investigated. This study analyzed the characteristics of lymph node (LN) involvement and the prognostic role of nodal metastases stratified by LN stations. Methods All upfront distal pancreatectomies (DPs) for PDAC (2000–2017) with complete information on station 8,10,11, and 18 were included. Clinico-pathological correlates and survival were investigated using uni- and multivaria...
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#1Matteo De PastenaH-Index: 7
Last. Chiara Ricci (UNIBO: University of Bologna)H-Index: 33
view all 14 authors...
BACKGROUND: This study analyzed the Quality of Life (QoL) and cost-effectiveness of laparoscopic (LDP) versus robotic distal pancreatectomy (RDP). METHOD: All patients who underwent LDP or RDP from 2011 to 2017 and with a minimum postoperative follow-up of 12 months were included in the study. To minimize bias, a propensity score-matched analysis (1:2) was performed. Two different questionnaires (EORTC QLQ-C30 and EQ-5D) were completed by the patients. The mean differential cost and mean differe...
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#1Tommaso Giuliani (University of Verona)H-Index: 1
#2Giovanni Marchegiani (University of Verona)H-Index: 19
Last. Luca Landoni (University of Verona)H-Index: 10
view all 14 authors...
BACKGROUND: Pancreatic enucleation (PE) is a viable option for the removal of non-malignant pancreatic masses leading to complete preservation of organ function. Nevertheless, PE is associated with substantial rates of post-operative pancreatic fistula (POPF), particularly when the mass is close to the main pancreatic duct (MPD). Preoperative stenting of the MPD may prevent its injury when performing PE. This paper describes a novel technique of "deep" PE preceded by endoscopic stenting of the M...
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#1Ajith K. Siriwardena (Manchester Royal Infirmary)H-Index: 31
#2John A. Windsor (University of Auckland)H-Index: 52
Last. Martin D. SmithH-Index: 29
view all 38 authors...
Abstract Background The International Study Group for Pancreatic Surgery provides globally accepted definitions for reporting of complications after pancreatic surgery. This International Study Group for Pancreatic Surgery project aims to provide a standardized framework for reporting of the results of operative treatment for chronic pancreatitis. Methods An International Study Group for Pancreatic Surgery project circulation list was created with pre-existing and new members and including gastr...
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BACKGROUND: Surgical-site infection (SSI) increases treatment costs, duration of hospital stay and readmission rate after pancreatic surgery. This study aimed to assess whether a wound protector could reduce the risk of superficial incisional SSI after pancreatoduodenectomy. METHODS: This RCT included patients undergoing pancreatoduodenectomy at Verona University Hospital, between 2017 and 2018. The experimental group had a dual-ring wound protector, whereas the control group had standard surgic...
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#1Marin Strijker (UvA: University of Amsterdam)H-Index: 4
#2E.C. Soer (UvA: University of Amsterdam)H-Index: 2
Last. Hanneke W. M. van Laarhoven (UvA: University of Amsterdam)H-Index: 30
view all 26 authors...
Circulating tumor DNA (ctDNA) is assumed to reflect tumor burden and has been suggested as a tool for prognostication and follow-up in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC). However, the prognostic value of ctDNA and its relation with tumor burden has yet to be substantiated, especially in mPDAC. In this retrospective analysis of prospectively collected samples, cell-free DNA from plasma samples of 58 treatment-naive mPDAC patients was isolated and sequenced using a c...
1 CitationsSource
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