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Jeanette C. Mostert
Radboud University Nijmegen
PsychiatryPsychologyNeurosciencePutamenAttention deficit hyperactivity disorder
13Publications
9H-index
895Citations
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Publications 13
Newest
#1Sarita A. Dam (Radboud University Nijmegen)
#2Jeanette C. Mostert (Radboud University Nijmegen)H-Index: 9
Last. Alejandro Arias-Vasquez (Radboud University Nijmegen)H-Index: 24
view all 6 authors...
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#1Jeanette C. Mostert (Radboud University Nijmegen)H-Index: 9
#2Martine Hoogman (Radboud University Nijmegen)H-Index: 25
Last. Barbara Franke (Radboud University Nijmegen)H-Index: 76
view all 11 authors...
Objective: To characterize heterogeneity in adults with ADHD we aimed to identify subgroups within the adult ADHD spectrum, which differ in their cognitive profile. Method: Neuropsychological data from adults with ADHD (n = 133) and healthy control participants (n = 132) were used in a confirmatory factor analysis. The resulting six cognitive factors were correlated across participants to form networks. We used a community detection algorithm to cluster these networks into subgroups. Results: Bo...
19 CitationsSource
#1Martine HoogmanH-Index: 25
#2Janita BraltenH-Index: 15
Last. John P FisherH-Index: 1
view all 248 authors...
124 CitationsSource
#1Martine Hoogman (Radboud University Nijmegen)H-Index: 25
#2Janita Bralten (Radboud University Nijmegen)H-Index: 15
Last. Barbara Franke (Radboud University Nijmegen)H-Index: 76
view all 82 authors...
Summary Background Neuroimaging studies have shown structural alterations in several brain regions in children and adults with attention deficit hyperactivity disorder (ADHD). Through the formation of the international ENIGMA ADHD Working Group, we aimed to address weaknesses of previous imaging studies and meta-analyses, namely inadequate sample size and methodological heterogeneity. We aimed to investigate whether there are structural differences in children and adults with ADHD compared with ...
255 CitationsSource
#1Jeanette C. Mostert (Radboud University Nijmegen)H-Index: 9
#2E. Shumskay (Radboud University Nijmegen)H-Index: 1
Last. David G. Norris (Radboud University Nijmegen)H-Index: 19
view all 6 authors...
Attention-deficit/hyperactivity disorder (ADHD) is a common childhood psychiatric disorder that often persists into adulthood. While several studies have identified altered functional connectivity in brain networks during rest in children with ADHD, few studies have been performed on adults with ADHD. Existing studies have generally investigated small samples. We therefore investigated aberrant functional connectivity in a large sample of adult patients with childhood-onset ADHD, using a data-dr...
20 CitationsSource
#1A. Marten H. Onnink (Radboud University Nijmegen)H-Index: 8
#2Barbara Franke (Radboud University Nijmegen)H-Index: 76
Last. Martine Hoogman (Radboud University Nijmegen)H-Index: 25
view all 14 authors...
The dopamine transporter gene, DAT1 (SLC6A3), has been studied extensively as a candidate gene for attention-deficit/hyperactivity disorder (ADHD). Different alleles of variable number of tandem repeats (VNTRs) in this gene have been associated with childhood ADHD (10/10 genotype and haplotype 10-6) and adult ADHD (haplotype 9-6). This suggests a differential association depending on age, and a role of DAT1 in modulating the ADHD phenotype over the lifespan. The DAT1 gene may mediate susceptibil...
11 CitationsSource
#1Barbara FrankeH-Index: 76
#2Janet L. SteinH-Index: 96
Last. Gunter SchumannH-Index: 51
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#1Barbara FrankeH-Index: 76
#2Janet L. SteinH-Index: 96
Last. Sarah E. MedlandH-Index: 77
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Schizophrenia is a devastating psychiatric illness with high heritability. Brain structure and function differ, on average, between people with schizophrenia and healthy individuals. As common genetic associations are emerging for both schizophrenia and brain imaging phenotypes, we can now use genome-wide data to investigate genetic overlap. Here we integrated results from common variant studies of schizophrenia (33,636 cases, 43,008 controls) and volumes of several (mainly subcortical) brain st...
#1A. Marten H. Onnink (Radboud University Nijmegen)H-Index: 8
#2Marcel P. Zwiers (Radboud University Nijmegen)H-Index: 38
Last. Barbara Franke (Radboud University Nijmegen)H-Index: 76
view all 10 authors...
Attention-deficit/hyperactivity disorder (ADHD) in childhood is characterized by gray and white matter abnormalities in several brain areas. Considerably less is known about white matter microstructure in adults with ADHD and its relation with clinical symptoms and cognitive performance. In 107 adult ADHD patients and 109 gender-, age- and IQ-matched controls, we used diffusion tensor imaging (DTI) with tract-based spatial statistics (TBSS) to investigate whole-skeleton changes of fractional ani...
33 CitationsSource
#1Jeanette C. Mostert (Radboud University Nijmegen)H-Index: 9
#2A. Marten H. Onnink (Radboud University Nijmegen)H-Index: 8
Last. Martine Hoogman (Radboud University Nijmegen)H-Index: 25
view all 12 authors...
Attention Deficit/Hyperactivity Disorder (ADHD) in childhood is associated with impaired functioning in multiple cognitive domains: executive functioning (EF), reward and timing. Similar impairments have been described for adults with persistent ADHD, but an extensive investigation of neuropsychological functioning in a large sample of adult patients is currently lacking. We systematically examined neuropsychological performance on tasks measuring EF, delay discounting, time estimation and respo...
40 CitationsSource
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