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Jacob P. Thyssen
University of Copenhagen
DermatologyAllergyAtopic dermatitisPopulationMedicine
526Publications
47H-index
9,681Citations
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Publications 524
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Insulin pump therapy and the use of flash or continuous glucose monitoring in children is increasing. The diabetes devices are attached to the skin for several days to weeks with a strong adhesive, and recently, several cases of allergic contact dermatitis in children caused by components of the adhesive have been reported. In this review, we discuss such problems. The most frequent cause of allergic contact dermatitis is acrylates in the adhesive material, and the problem is serious and calls f...
#1Charlotte Näslund-Koch (Gentofte Hospital)
#2Jacob P. Thyssen (UCPH: University of Copenhagen)H-Index: 47
Last. Lone Skov (UCPH: University of Copenhagen)H-Index: 42
view all 5 authors...
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#1Jacob P. Thyssen (Gentofte Hospital)H-Index: 47
#2Christian Vestergaard (Aarhus University Hospital)H-Index: 28
Last. Carsten Flohr (Guy's and St Thomas' NHS Foundation Trust)H-Index: 33
view all 31 authors...
Letters to the Editor should not have an abstract nor acknowledgements, should be formatted in one continuous section (no subheadings) and should not exceed 600 words, 10 references and a total of 2 figures; or 2 tables; or 1 figure and 1 table. No supplementary material (figure, table or text) is allowed when submitting a Letter to the Editor. All letters are published online-only, although they are each published as a part of a specific issue. Atopic dermatitis (AD), a common inflammatory skin...
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#1Jonathan I. Silverberg (GW: George Washington University)H-Index: 3
#2Eric L. Simpson (OHSU: Oregon Health & Science University)H-Index: 32
Last. Chudy I. Nduaka (Pfizer)H-Index: 12
view all 11 authors...
Importance Abrocitinib, an oral, once-daily Janus kinase 1 selective inhibitor, was effective and well tolerated in a phase 3 monotherapy trial of patients with moderate-to-severe atopic dermatitis (AD). Objective To investigate the efficacy and safety of abrocitinib in adolescents and adults with moderate-to-severe AD in an identically designed trial. Design, Setting, and Participants This phase 3, double-blinded, placebo-controlled, parallel-group randomized clinical trial included patients 12...
1 CitationsSource
#1Helen Alexander (Guy's and St Thomas' NHS Foundation Trust)H-Index: 2
#1H. Alexander (Guy's and St Thomas' NHS Foundation Trust)
Last. Carsten Flohr (Guy's and St Thomas' NHS Foundation Trust)H-Index: 33
view all 16 authors...
Patients with atopic dermatitis (AD) have an increased risk of bacterial skin infections, which cause significant morbidity and, if untreated, may become systemic. Staphylococcus aureus colonizes the skin of most patients with AD and is the most common organism to cause infections. Overt bacterial infection is easily recognized by the appearance of weeping lesions, honey-coloured crusts and pustules. However, the wide variability in clinical presentation of bacterial infection in AD and the inhe...
2 CitationsSource
#1A.L. BosmaH-Index: 2
#2Ph.I. SpulsH-Index: 30
Last. Eulalia BaselgaH-Index: 36
view all 29 authors...
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#1A.L. Bosma (UvA: University of Amsterdam)H-Index: 2
#2Ph.I. Spuls (UvA: University of Amsterdam)H-Index: 30
Last. Carsten Flohr ('KCL': King's College London)H-Index: 33
view all 29 authors...
Background: A long-term prospective observational safety study is essential to characterize fully the safety profile of systemic immunomodulating therapies for patients with atopic eczema. The TREatment of ATopic eczema (TREAT) Registry Taskforce offers a large platform to conduct such research using national registries that collect the same data using a predefined core dataset. Objectives: To present a protocol for a safety study comparing dupilumab with other systemic immunomodulating therapie...
2 CitationsSource
#1A.L. BosmaH-Index: 2
#2Ph.I. SpulsH-Index: 30
Last. Eulalia BaselgaH-Index: 36
view all 29 authors...
Source
#1Jacob P. Thyssen (UCPH: University of Copenhagen)H-Index: 47
#2A.‐S. Halling‐Sønderby (UCPH: University of Copenhagen)H-Index: 1
Last. Alexander Egeberg (UCPH: University of Copenhagen)H-Index: 24
view all 4 authors...
BACKGROUND: Adult patients with atopic dermatitis (AD) report skin pain, but the relationship with disease severity, anatomical location and use of pain medication is unclear. OBJECTIVES: To examine pain in adults with AD. METHODS: We performed a cross-sectional study of nationwide healthcare data and survey data from the Danish Skin Cohort. In total, 3208 randomly selected adults from the general population and 3834 adults with a dermatologist-verified diagnosis of AD present in adulthood were ...
1 CitationsSource
#1T.H. Andreasen (UCPH: University of Copenhagen)
Last. Jacob P. Thyssen (UCPH: University of Copenhagen)H-Index: 47
view all 6 authors...
Netherton syndrome (NS), ichthyosis linearis circumflexa, is a rare autosomal recessive disorder. NS is caused by pathogenic loss-of-function variants in the serine protease inhibitor of Kazal type 5 gene (SPINK5), compromising lymphoepithelial Kazal type 1 inhibitor (LEKTI-1) function. The unopposed serine protease activity due to reduced LEKTI-1 inhibition in NS leads to premature degradation of corneodesmosomes, causing decreased stratum corneum cohesion and thinning.
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