Falk Kiefer
Heidelberg University
PsychiatryPsychologyAlcohol dependenceClinical psychologyMedicine
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Publications 399
#1Patrick Bach (Heidelberg University)H-Index: 9
#2Anne Koopmann (Heidelberg University)H-Index: 11
Last. Falk Kiefer (Heidelberg University)H-Index: 43
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The neuroprotective effects of leptin and its role in addictive disorders has been highlighted by several recent studies. However, its potential effects on morphological alterations in alcohol dependence are yet to be investigated. Associations between leptin and the longitudinal courses of gray matter volume (GMV) and cortical thickness (CT) were investigated in N=62 alcohol-dependent patients that underwent structural magnetic resonance imaging after a mean abstinence of 12 (baseline) and 27da...
#1Franziska Weiss (Heidelberg University)H-Index: 1
#2Acelya Aslan (Heidelberg University)
Last. Peter Kirsch (Heidelberg University)H-Index: 50
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BACKGROUND Alcohol Use Disorder is a severe mental disorder affecting the individuals concerned, their family and friends and society as a whole. Despite its high prevalence, novel treatment options remain rather limited. Two innovative interventions used for treating severe disorders are the use of real-time functional magnetic resonance imaging neurofeedback that targets brain regions related to the disorder, and mindfulness-based treatments. In the context of the TRR SFB 265 C04 "Mindfulness-...
#1Patrick Bach (Heidelberg University)H-Index: 9
#2Anne Koopmann (Heidelberg University)H-Index: 11
Last. Falk Kiefer (Heidelberg University)H-Index: 43
view all 3 authors...
AIMS The appetite regulating hormone leptin, which is mainly secreted from adipose tissue, is an important regulator of food intake and modulator of reward-driven behavior. Leptin exerts its biological actions via binding to the leptin receptor, which is expressed in the hypothalamus, but also in the hippocampus, the amygdala and the substantia nigra. In the ventral tegmental area (VTA), leptin attenuates the firing rate of dopaminergic neurons that project to the Nucleus accumbens (NAc), which ...
#1Shuyan Liu (Charité)H-Index: 2
#2Anne Beck (Charité)H-Index: 22
Last. Andreas Heinz (Charité)H-Index: 86
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#1Sabine Vollstädt-Klein (Heidelberg University)H-Index: 23
#2S Gerhardt (Heidelberg University)
Last. Derik Hermann (Heidelberg University)H-Index: 29
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RATIONALE: Compared to the general population, adult Attention-Deficit / Hyperactivity Disorder (ADHD) is more prevalent in patients with Alcohol Use Disorder (AUD). Impaired behavioral inhibition is a common characteristic in both ADHD and AUD. Relapse risk is increased in patients with AUD and comorbid, untreated ADHD and in AUD patients with increased neural cue-reactivity. OBJECTIVES: In this study, we examined the interaction between neural correlates of behavioral inhibition and alcohol cu...
#1Falk KieferH-Index: 43
#2Nina Kim BekierH-Index: 1
Last. Christoph HiemkeH-Index: 48
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Zusammenfassung. Das Jugendalter ist eine besonders kritische Lebensphase fur die Entwicklung von Suchterkrankungen und komorbiden psychischen Storungen. Substanzbezogene Storungen gehoren zu den a...
#1Rainer ThomasiusH-Index: 20
#2Nicolas ArnaudH-Index: 8
Last. Falk Kiefer (Heidelberg University)H-Index: 43
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Substance-related disorders in adolescence and young adulthood Abstract. Adolescence is a critical period for the onset of addiction and comorbid psychological disorders. Although substance use disorders (SUD) are among the most prevalent psychiatric conditions and a leading cause for hospitalization in the young population, young people with SUD can be considered an underserved population. Existing capacities for the provision of specific health services including withdrawal treatment for young...
#1Andreas Heinz (Charité)H-Index: 86
#2Falk Kiefer (Heidelberg University)H-Index: 43
Last. Rainer Spanagel (Heidelberg University)H-Index: 74
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One of the major risk factors for global death and disability is alcohol, tobacco, and illicit drug use. While there is increasing knowledge with respect to individual factors promoting the initiation and maintenance of substance use disorders (SUDs), disease trajectories involved in losing and regaining control over drug intake (ReCoDe) are still not well described. Our newly formed German Collaborative Research Centre (CRC) on ReCoDe has an interdisciplinary approach funded by the German Resea...
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