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John C. Mathers
Newcastle University
614Publications
65H-index
14.6kCitations
Publications 619
Newest
#2N. D. WillisH-Index: 5
Last.D. M. BradburnH-Index: 13
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#1Khalil ElGendy (Newcastle University)H-Index: 1
#2F. Malcomson (Newcastle University)H-Index: 1
Last.John C. Mathers (Newcastle University)H-Index: 65
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ABSTRACT: Setting DNA methylation is an epigenetic mechanism through which environmental factors, including obesity influence health. Obesity is a major modifiable risk factor for many common diseases including cardiovascular diseases and cancer. Obesity-induced metabolic stress and inflammation are key mechanisms that affect disease risk and which may result from changes in methylation of metabolic and inflammatory genes. Objectives This review aims to report the effects of weight loss induced ...
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#1Ahmad Al-Mrabeh (Newcastle University)H-Index: 10
#2Sviatlana Zhyzhneuskaya (Newcastle University)H-Index: 5
Last.Roy Taylor (Newcastle University)H-Index: 47
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Summary The role of hepatic lipoprotein metabolism in diet-induced remission of type 2 diabetes is currently unclear. Here, we determined the contributions of hepatic VLDL1-triglyceride production rate and VLDL1-palmitic acid content to changes in intra-pancreatic fat and return of first phase insulin response in a subgroup of the Diabetes Remission Clinical Trial. Liver fat, VLDL1-triglyceride production, and intra-pancreatic fat decreased after weight loss and remained normalized after 24 mont...
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#1Thomas Wilson (Aberystwyth University)H-Index: 5
#2Isabel Garcia-Perez (Imperial College London)H-Index: 14
Last.John Draper (Aberystwyth University)H-Index: 30
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#1Oliver M. ShannonH-Index: 6
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Background In Mediterranean countries, adherence to a traditional Mediterranean dietary pattern (MedDiet) is associated with better cognitive function and reduced dementia risk. It is unclear if similar benefits exist in non-Mediterranean regions. Objective To examine associations between MedDiet adherence and cognitive function in an older, UK population. To investigate whether associations differed between individuals with high versus low cardiovascular disease (CVD) risk. Design We conducted ...
1 Citations
#1Oliver M. Shannon (Newcastle University)H-Index: 6
#2Blossom C. M. Stephan (Newcastle University)H-Index: 35
Last.Mario Siervo (Newcastle University)H-Index: 34
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Background In Mediterranean countries, adherence to a traditional Mediterranean dietary pattern (MedDiet) is associated with better cognitive function and reduced dementia risk. It is unclear if similar benefits exist in non-Mediterranean regions. Objective To examine associations between MedDiet adherence and cognitive function in an older, UK population. To investigate whether associations differed between individuals with high versus low cardiovascular disease (CVD) risk. Design We conducted ...
2 CitationsSource
#1Christie Walker (ETH Zurich)H-Index: 2
#2Eileen R. Gibney (UCD: University College Dublin)H-Index: 27
Last.Stefanie Hellweg (ETH Zurich)H-Index: 47
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Abstract Dietary choices affect personal health and environmental impacts, but little is known about the relation between these outcomes. Here we examine the intake-related health impacts and the food-production related impacts to ecosystems and human health by applying life cycle impact assessment methods to habitual diet data of 1457 European adults. We measured food production impacts for each individual in terms of Disability Adjusted Life Years (DALYs) as calculated by the Recipe 2016 life ...
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#1Oliver M. Shannon (Newcastle University)H-Index: 6
#2Giorgia Grisotto (Newcastle University)
Last.Mario SiervoH-Index: 34
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Objectives To examine knowledge and beliefs about the biological roles of dietary inorganic nitrate in UK-based nutrition professionals, and to explore potential differences by participants’ education level. Setting An online questionnaire was administered to UK-based nutrition professionals, exploring knowledge and/or beliefs across five areas: (1) health and performance effects of nitrate; (2) current and recommended intake values for nitrate; (3) dietary sources of nitrate; (4) methods of eva...
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#1Abrar Babateen (Newcastle University)H-Index: 2
#2Oliver M. Shannon (Newcastle University)H-Index: 6
Last.Mario Siervo (Newcastle University)H-Index: 34
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Abstract The nitrate (NO 3 − )-nitrite (NO 2 − )-nitric oxide (NO) pathway has received considerable interest in recent years as a potential target for nutritional interventions designed to increase NO production, and elicit therapeutic effects in humans. In particular, studies have evaluated the effects of supplemental dietary NO 3 − , which serves as a ‘substrate’ for this pathway, on numerous different health outcomes. One challenge has been to evaluate compliance with the NO 3 − intervention...
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#1Khalil ElGendyH-Index: 1
#2F. MalcomsonH-Index: 1
Last.John C. MathersH-Index: 65
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