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Eva Obermayr
Medical University of Vienna
25Publications
8H-index
361Citations
Publications 25
Newest
#1Konstantina Panoutsopoulou (UoA: National and Kapodistrian University of Athens)H-Index: 1
#2Margaritis Avgeris (UoA: National and Kapodistrian University of Athens)H-Index: 14
Last.Andreas Scorilas (UoA: National and Kapodistrian University of Athens)H-Index: 51
view all 16 authors...
#1Eva ObermayrH-Index: 8
Last.Robert ZeillingerH-Index: 36
view all 9 authors...
At initial diagnosis, most patients with small-cell lung cancer (SCLC) present with metastatic disease with a high number of tumor cells (CTCs) circulating in the blood. We analyzed RNA transcripts specific for neuroendocrine and for epithelial cell lineages, and Notch pathway delta-like 3 ligand (DLL3), the actionable target of rovalpituzumab tesirine (Rova-T) in CTC samples. Peripheral blood samples from 48 SCLC patients were processed using the microfluidic Parsortix™ technology to enrich the...
#1Elisabeth Maritschnegg (Medical University of Vienna)H-Index: 3
#2Florian HeitzH-Index: 25
Last.Paul Speiser (Medical University of Vienna)H-Index: 23
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Objectives Poor survival of high-grade serous pelvic cancer is caused by a lack of effective screening measures. The detection of exfoliated cells from high-grade serous pelvic cancer, or precursor lesions, is a promising concept for earlier diagnosis. However, collecting those cells in the most efficient way while fulfilling all requirements for a screening approach is a challenge. We introduce a new catheter for uterine and tubal lavage (UtL) and the clinical evaluation of its performance. Met...
#1Johanna M. Gostner (Innsbruck Medical University)H-Index: 16
#2Eva Obermayr (Medical University of Vienna)H-Index: 8
Last.Robert Zeillinger (Medical University of Vienna)H-Index: 29
view all 10 authors...
Abstract Objective Circulating tumor cells (CTCs) may represent a chronic stimulus for the immune system. In the present study we investigated the potential association of CTCs, the immune activation marker neopterin, and the ratio of kynurenine to tryptophan (Kyn/Trp) as a measure for tryptophan breakdown. Methods Neopterin, tryptophan and kynurenine levels were measured in plasma samples from patients with benign gynecological diseases ( n =65) and with primary advanced epithelial ovarian canc...
#1Eva ObermayrH-Index: 8
Last.Robert ZeillingerH-Index: 36
view all 10 authors...
// Eva Obermayr 1 , Elisabeth Maritschnegg 1 , Christiane Agreiter 1 , Nina Pecha 1, 2 , Paul Speiser 1, 2 , Samir Helmy-Bader 2 , Sabine Danzinger 3 , Michael Krainer 4 , Christian Singer 3 and Robert Zeillinger 1 1 Molecular Oncology Group, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria 2 Department of Obstetrics and Gynecology, Clinical Division for General Gynecology and Gynecological Oncology...
#1Eva ObermayrH-Index: 8
Last.Burkhard BrandtH-Index: 44
view all 14 authors...
// Eva Obermayr 1 , Natalia Bednarz-Knoll 2 , Beatrice Orsetti 3, 4 , Heinz-Ulrich Weier 5 , Sandrina Lambrechts 6 , Dan Cacsire Castillo-Tong 1 , Alexander Reinthaller 1 , Elena Ioana Braicu 7 , Sven Mahner 8, 10 , Jalid Sehouli 7 , Ignace Vergote 6 , Charles Theillet 3, 4 , Robert Zeillinger 1, * and Burkhard Brandt 9, * 1 Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria 2 Institute of Tumor Biology, University Medical Center Eppendorf, Hamburg, Germany 3 ...
#1Elisabeth Maritschnegg (Medical University of Vienna)H-Index: 3
#2Eva Obermayr (Medical University of Vienna)H-Index: 8
Last.Robert Zeillinger (Medical University of Vienna)H-Index: 29
view all 13 authors...
75% of ovarian cancer (OC) cases are detected at an advanced stage. State–of–the–art diagnostic tools don9t show sufficient sensitivity, especially in diagnosing early–stage disease. Still, due to lack in alternatives, these methods are used for monitoring BRCA mutation carriers, who face a high penetrance of OC. A 41–year old BRCA1 mutation carrier decided to undergo risk–reducing bilateral salpingo–oophorectomy (rrBSO), currently the only effective way of reducing the OC risk. The day before s...
#1Eva Obermayr (Medical University of Vienna)H-Index: 8
#2Elisabeth Maritschnegg (Medical University of Vienna)H-Index: 3
Last.Robert Zeillinger (Medical University of Vienna)H-Index: 29
view all 7 authors...
PURPOSE OF THE STUDY: The detection of circulating tumor cells (CTCs) in the blood of cancer patients has raised considerable interest over the last decade as a promising biomarker of minimal residual disease in various solid tumors. Although hematogenous spread has not been deemed a major issue for ovarian cancer, there are several studies demonstrating the presence and prognostic impact of CTCs in ovarian cancer patients. Recently, we developed a protocol for the enrichment of CTCs from ovaria...
#1Stefanie Aust (Medical University of Vienna)H-Index: 14
#2Thomas Knogler (Medical University of Vienna)H-Index: 5
Last.Stephan Polterauer (Medical University of Vienna)H-Index: 18
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Objective Tumor cachexia is an important prognostic parameter in epithelial ovarian cancer (EOC). Tumor cachexia is characterized by metabolic and inflammatory disturbances. These conditions might be reflected by body composition measurements (BCMs) ascertained by pre-operative computed tomography (CT). Thus, we aimed to identify the prognostically most relevant BCMs assessed by pre-operative CT in EOC patients. Methods We evaluated muscle BCMs and well established markers of nutritional and inf...
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