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Philippa C. Griffin
University of Melbourne
EcologyPopulationGeneticsBotanyBiology
38Publications
11H-index
603Citations
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Publications 37
Newest
#1Megan J. Hirst (University of Melbourne)H-Index: 3
#2Philippa C. Griffin (University of Melbourne)H-Index: 11
Last. Ary A. Hoffmann (University of Melbourne)H-Index: 97
view all 4 authors...
Source
#1Thomas L. Schmidt (University of Melbourne)H-Index: 5
Last. Andrew R. Weeks (University of Melbourne)H-Index: 38
view all 8 authors...
: Biological invasions are increasing globally in number and extent despite efforts to restrict their spread. Knowledge of incursion pathways is necessary to prevent new invasions and to design effective biosecurity protocols at source and recipient locations. This study uses genome-wide single nucleotide polymorphisms (SNPs) to determine the origin of 115 incursive Aedes aegypti(yellow fever mosquito) detected at international ports in Australia and New Zealand. We also genotyped mosquitoes at ...
4 CitationsSource
#1Bryant Gagliardi (University of Melbourne)H-Index: 4
#2Sara M. Long (University of Melbourne)H-Index: 13
Last. Ary A. Hoffmann (University of Melbourne)H-Index: 97
view all 5 authors...
: Larval deformities have been observed in chironomids, and are thought to be associated with aquatic contaminant exposure. However, in laboratory assays, deformities have not been linked with contaminants in the absence of potential confounding variables including mortality, which introduces a survivorship bias. There is also a paucity of data on noncontaminant causes. In addition, power analyses are rarely undertaken, meaning that effect sizes detectable are usually uncertain. We therefore aim...
Source
#1Kelly M. Richardson (University of Melbourne)H-Index: 7
#2Philippa C. Griffin (University of Melbourne)H-Index: 11
Last. Ary A. Hoffmann (University of Melbourne)H-Index: 97
view all 7 authors...
Wolbachia bacteria are common insect endosymbionts transmitted maternally and capable of spreading through insect populations by cytoplasmic incompatibility (CI) when infected males cause embryo death after mating with uninfected females. Selection in the Wolbachia endosymbiont occurs on female hosts and is expected to favour strong maternal transmission to female offspring, even at the cost of reduced CI. With maternal leakage, nuclear genes are expected to be selected to suppress cytoplasmic i...
7 CitationsSource
#1Maria Victoria Schneider (University of Melbourne)H-Index: 24
#2Philippa C. Griffin (Australia Bioinformatics Resource)H-Index: 11
Last. Andrew Lonie (University of Melbourne)H-Index: 18
view all 18 authors...
EMBL Australia Bioinformatics Resource (EMBL-ABR) is a developing national research infrastructure, providing bioinformatics resources and support to life science and biomedical researchers in Australia. EMBL-ABR comprises 10 geographically distributed national nodes with one coordinating hub, with current funding provided through Bioplatforms Australia and the University of Melbourne for its initial 2-year development phase. The EMBL-ABR mission is to: (1) increase Australia’s capacity in bioin...
4 CitationsSource
#1Rahul V. Rane (University of Melbourne)H-Index: 8
#2Stephen L. Pearce (CSIRO: Commonwealth Scientific and Industrial Research Organisation)H-Index: 7
Last. John G. Oakeshott (CSIRO: Commonwealth Scientific and Industrial Research Organisation)H-Index: 54
view all 12 authors...
Insights into the genetic capacities of species to adapt to future climate change can be gained by using comparative genomic and transcriptomic data to reconstruct the genetic changes associated with such adaptations in the past. Here we investigate the genetic changes associated with adaptation to arid environments, specifically climatic extremes and new cactus hosts, through such an analysis of five repleta group Drosophila species. We find disproportionately high rates of gene gains in intern...
6 CitationsSource
#1Thomas L. Schmidt (University of Melbourne)H-Index: 5
Last. Andrew R. WeeksH-Index: 38
view all 8 authors...
Biological invasions are increasing globally in number and extent despite concerted efforts to restrict their spread. Knowledge of incursion pathways is necessary to prevent new invasions and to design more effective biosecurity protocols at source and recipient locations. In this study, we use genome-wide single-nucleotide polymorphisms (SNPs) and reference mosquitoes from 15 locations to determine the origin of 115 incursive Aedes aegypti (yellow fever mosquito) collected at international port...
1 CitationsSource
#1Nicholas Bell (University of Melbourne)H-Index: 2
#2Philippa C. Griffin (Australia Bioinformatics Resource)H-Index: 11
Last. Adam D. Miller (Deakin University)H-Index: 17
view all 4 authors...
1 CitationsSource
#1Megan J. Hirst (University of Melbourne)H-Index: 3
#2Philippa C. Griffin (University of Melbourne)H-Index: 11
Last. Ary A. Hoffmann (University of Melbourne)H-Index: 97
view all 4 authors...
Relatively common species within a clade are expected to perform well across a wider range of conditions than their rarer relatives, yet experimental tests of this “niche breadth—range size” hypothesis remain surprisingly scarce. Rarity may arise due to trade-offs between specialization and performance across a wide range of environments. Here we use common garden and reciprocal transplant experiments to test the niche breadth—range size hypothesis, focusing on four common and three rare endemic...
4 CitationsSource
#1Philippa C. Griffin (University of Melbourne)H-Index: 11
#2Jyoti Khadake (Cambridge University Hospitals NHS Foundation Trust)H-Index: 12
Last. Maria Victoria Schneider (University of Melbourne)H-Index: 24
view all 27 authors...
Throughout history, the life sciences have been revolutionised by technological advances; in our era this is manifested by advances in instrumentation for data generation, and consequently researchers now routinely handle large amounts of heterogeneous data in digital formats. The simultaneous transitions towards biology as a data science and towards a ‘life cycle’ view of research data pose new challenges. Researchers face a bewildering landscape of data management requirements, recommendations...
3 CitationsSource
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